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Isoprinosine

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Gail,

Please clear up some confusion that I have. In your post you talk about " us "

not having side effects, I infer that you are part of the " us " group with

CFS. Did you try Isoprinosine? I thought that you didn't have CFS, that your

daughter did.

Barb S

<< It didn't seem to

have many severe side effects....most were mild, but it didn't seem to help

any of us, either. The company called me two days ago and wanted to meet

with me in Boston. I just told them to send material. Their group only was

comprised of 19 patients....very small for a study. Maybe they've improved

on it.....but it's wait and see right now. I don't think it's harmful to

try, though. At least, none of us is the worse for it, but no better,

either.

Gail

>>

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In a message dated 6/19/99 9:06:31 PM Eastern Daylight Time, KB46@...

writes:

<< I thought that you didn't have CFS, that your

daughter did.

>>

We both do, but I'm not half as severe as she is. I had an aburpt onset when

I was a child, but it didn't worsen. She had a gradual onset from a much

younger age, though, like April, I didn't understand a lot of it. It wasn't

until she was seventeen that a " virus " started her on a progressive trip

downhill.

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I was 10 but Dr. Bell thinks my daughter, from her medical history, has had

it most of her life. She was a really placid baby....my sister wondered if I

should have her tested for retardation!!! She'd sit in one place, as a baby,

and play happily for a long time....never crawled....just walked one day!

When she began school, she needed naps right after school or was

impossible...up to and including third grade! Does any of this sound

familiar? She always complained about her legs hurting and stomach aches a

bit after meals and never liked really active sports. Of course, the

pediatrician attributed everything to growing pains or just looking for more

quality time.....and she had plenty of that! But don't blame yourself for

not knowing. I'm sure you had similar experiences. Kim told me years later

that she never got her " chores " done because she didn't care if she got ice

cream from the ice cream man...she hated running after the truck anyway

because it hurt. They say so little at the time because they don't know

themselves. Let's hope your daughter never gets worse....or if she does,

science will have beat her to it with a real treatment.

Gail

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In a message dated 6/19/99 10:19:12 PM Eastern Daylight Time,

SWNGDABOAT@... writes:

<<

Do you mean prednisone? >>

No, it's no relation. Prednisone is a steroid. This isn't.

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  • 2 months later...

I don't believe this is available in the states yet......

<< Saturday September 11, 12:20 pm Eastern Time

Company Press Release

Helix BioPharma Corp.: Isoprinosine Successful In Treating Chronic Fatigue

AURORA, ONTARIO--(BW HealthWire)--Sept. 11, 1999--(TSE:HBP. - news)

Patients

suffering from Chronic Fatigue Syndrome (``CFS'') who were treated with

Isoprinosine® showed a significant reduction of their clinical symptoms

and a

significant improvement in their immune system function.

Isoprinosine® is an anti-viral and immune modulating drug. It is approved

in

Canada and in many other countries for the treatment of certain viral

infections and disorders of the immune system.

Renowned CFS specialist, Dr. Byron Hyde of the Ottawa-based Nightingale

Foundation, presented the results of his seven-month placebo controlled

clinical study at a conference in Brussels today.

The clinical study showed that 50 percent of the 16 patients in this study

who were treated with Isoprinosine® demonstrated considerable improvement

of

the symptoms as well as increased immune function, including immune memory

for common infectious agents. One patient even improved to the point of

being

able to return to work. Furthermore, there was no worsening of symptoms in

any of the patients treated with Isoprinosine®.

``Our study of Isoprinosine® is a milestone in the treatment of CFS. I

believe that this medication, with its proven safety record, holds the

promise of an improvement in the quality of life for some CFS patients,''

stated Dr. Hyde.

Isoprinosine® is distributed in Canada exclusively by Helix's subsidiary,

Rivex Pharma Inc.

Approximately 500,000 people in North America are believed to suffer from

Chronic Fatigue Syndrome, many of whom are unable to work due to the

debilitating nature of the disorder. Patients typically exhibit impaired

cognitive ability, profound fatigue and disregulation of the immune system.

Isoprinosine® is a registered trademark of Newport Pharmaceuticals Ltd.

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Hi Ann,

Where is this small blurb, did I miss an earlier post? Thanks.

Regards, .

Isoprinosine

> From: SWNGDABOAT@...

>

> HI,

> I saw a small 'blurb' about this (new?) med MD's are using for CFIDS

> treatment and wondered if anyone has had any experience with it? There

was a

> 50% " success " rating w/it's use.....to the point where some patients were

> well enough to return to work. Then I realized the " clinical trial "

published

> was with only 8 people, so we're talking 4 people felt better....even so,

if

> even ONE " got well enough " to return to work......impressive. Also,

> supposedly no one taking it " got worse " ...just wondering if anyone had any

> info or has heard anything. Thanks! Ann

>

> > This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

>

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  • 4 years later...

Thanks !

good to see Dr Hyde involved.

Is this something that might be a possibility

for our kids?

doris

land

<cut>

Clinical Improvement in Chronic Fatigue Syndrome Is Associated with

Enhanced Natural Killer Cell-Mediated Cytotoxicity:

The Results of a Pilot Study with Isoprinosine®

Journal: J of Chronic Fatigue Syndrome, Vol. 11(2) 2003, pp. 71-95

Authors: Francisco -Mitoma, MD, PhD, FRCP©; Eva Turgonyi, MD;

Ashok Kumar, PhD; Wilfred Lim; Louise Larocque; Byron M. Hyde, MD

//message trunctaed//

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