Re: Zippy/ cortef Doris Brown

[Guest guest]

Doris,

I sorry you read a " know it all attitude " in my message. Maybe its

because I am in such a hurry to post since my online time is limited?

For your own information, I been working on cortisol boosting

techniques in CFS since 1987, longer than anyone I know of other that

Dr. Baschetti in Italy. You see, we believe that CFS is an illness

whereby the H/P/A axis does not respond to stress. The body can

demand up to 300 mg/day of cortisol during severely stressful

periods. Therefore, for the body to demand 100 mg/day might be

common in folks under severe stress. Modern medicine says this

increase in cortisol is not good for us and causes hypertension and

etc. Maybe so... but why does the body pump out so much cortisol if

it is not " good " for us? Why all the cortisol? Anyway, since

cortisol serves as the brakes on immunity, we think the inability of

the H/P/A axis to meet the increased cortisol demand of the body

during stress (over time) leads to immune disregulation and

hyperimmunity. We think hyperimmunity is at the root of most of the

symptoms of CFS. We believe if you tone down the hyperimmunity, then

you tone down the symptoms of CFS.

Since the H/P/A axis supplies cortisol to the body is fits and starts

and squirts based on the level of stress, we think supplying 10

mg/day on a steady basis -- disregarding the stress factor -- makes

no friggin medical sense whatsoever and we are a bit pissed off at

the stupid doctors who have published this work. We think doctors

like Tallenbaum and Jeffereis and the recent bunch of idots that did

the cortsiol studies should be sent to jail for the shameful bullshit

they published. These idiots are suppose to know better. We think

this stuff got published simply because the doctors were able to get

a $$$$grant$$$$ to study low doses cortisol. They likely kicked back

half the $$$$$money$$$$$ they got to whoever gave them the grant. In

other words, low dose cortisol made no sense to begin with.

The only way to evaluate use of cortisol boosting in CFS is to try as

best you can to duplicate the way the H/P/A axis works. This means

no regular daily dosing. This also means dosing in fits and starts

and squirts depending on the level of stress faced by the PWC.

Difficult... no doubt about it ... but his is the only way we will

ever learn anything about cortisol and CFS. WE also believe that

exercise stress testing cortisol levels is a gaint leap forward for

CFS care. We pray that a few doctors might read these words and that

realility might sink in and maybe we can get some really valuable

research done and quit wasting time and money on stupid science.

Anyway, I guess I do sound a bit like a know it all when compared to

the other idiots working in the same area of research. hummm, maybe

I do know more than any one lese on the planet about boosting

cortisol in CFS at this point in time?

Dave

> May I ask what makes you the only person on the planet that has all

the answers about CFS? I'm sorry to be rude, but you act as if you

know how this works, nobody knows exactly how this works. Plenty of

PWC's say that low dose corisol in various forms works for them.

Also many doctors and scientists say that all the evidence you are

talking about concerning hydrocortisone was based on studies of doses

much higher than are used now and that true low dose does not

suppress adrenals.

>

> I am glad to hear both sides, it is good to keep us on our toes.

It sounds like some people get improvement and some get worse. And

the B6 warning is good. So I apologize if I sound too harsh. But

there is so much evidence contrary to what you are saying that if you

are going to state your case as fact I would like the references to

review.

> Thanks,

> Doris

> ----- Original Message -----

> From: D

> Your failure is to be expected since there is no scientific or

> medical validity behind low dose hydrocortisone. The HPA axis

simply

> resets your own production and you are back to level zero within

a

> day or so. ...

> Again... there is no validity to the science behind the low dose

> hydrocortione. CFS is an illness wherein the H/P/A fails to

respond

> to stress. CFS is not an illness of low cortisol under

conditions of

> no stress... STRESS is the key to understanding the failure of

the

> adrenal glands in CFS. Unless the stress-factor is inserted into

> your treatment protocol -- failure is assured.

>

>

[Guest guest]

Dave,

As you know, for two months this summer I had good results using your

ETD protocol. It makes a lot more sense than everyday low dosages of

hydrocortisone because of the HPA feedback mechanism. You are quite

right that with daily dosages the body adjusts and you end up back

where you started, which is why so many studies indicate that daily

low dosages of hydrocortisone don't help patients with CFS.

However, cortisol in not the only hormone that may be deficient in

CFS patients. One study, referenced on your own site, found that

patients with CFS have adrenals 50% or smaller than a normal control

group. If our adrenals can't produce enough cortisol because of this

problem, then it likely that our adrenals can't produce enough of the

other 80 odd hormones they are responsible for making and secreting.

Chief among these hormones is epinephrine (adrenaline). If this is

the case, then taking hydrocortisone may actually deplete the ability

of our adrenals to make other hormones, especially epinephrine.

Epinephrine is also crucial in maintaining adequate blood pressure

levels, especially upon standing from a prone position. As you also

know, I crashed on the ETD protocol this summer and now suspect this

is what happened to me. I may have run my adrenals into the ground

trying to produce sufficient epinephrine (and other key hormones) to

keep up with higher exercise and activity levels, made possible by

the hydrocortisone supplements.

- don

> Doris,

>

> I sorry you read a " know it all attitude " in my message. Maybe its

> because I am in such a hurry to post since my online time is

limited?

>

> For your own information, I been working on cortisol boosting

> techniques in CFS since 1987, longer than anyone I know of other

that

> Dr. Baschetti in Italy. You see, we believe that CFS is an illness

> whereby the H/P/A axis does not respond to stress. The body can

> demand up to 300 mg/day of cortisol during severely stressful

> periods. Therefore, for the body to demand 100 mg/day might be

> common in folks under severe stress. Modern medicine says this

> increase in cortisol is not good for us and causes hypertension and

> etc. Maybe so... but why does the body pump out so much cortisol

if

> it is not " good " for us? Why all the cortisol? Anyway, since

> cortisol serves as the brakes on immunity, we think the inability

of

> the H/P/A axis to meet the increased cortisol demand of the body

> during stress (over time) leads to immune disregulation and

> hyperimmunity. We think hyperimmunity is at the root of most of the

> symptoms of CFS. We believe if you tone down the hyperimmunity,

then

> you tone down the symptoms of CFS.

>

> Since the H/P/A axis supplies cortisol to the body is fits and

starts

> and squirts based on the level of stress, we think supplying 10

> mg/day on a steady basis -- disregarding the stress factor -- makes

> no friggin medical sense whatsoever and we are a bit pissed off at

> the stupid doctors who have published this work. We think doctors

> like Tallenbaum and Jeffereis and the recent bunch of idots that

did

> the cortsiol studies should be sent to jail for the shameful

bullshit

> they published. These idiots are suppose to know better. We think

> this stuff got published simply because the doctors were able to

get

> a $$$$grant$$$$ to study low doses cortisol. They likely kicked

back

> half the $$$$$money$$$$$ they got to whoever gave them the grant.

In

> other words, low dose cortisol made no sense to begin with.

>

> The only way to evaluate use of cortisol boosting in CFS is to try

as

> best you can to duplicate the way the H/P/A axis works. This means

> no regular daily dosing. This also means dosing in fits and starts

> and squirts depending on the level of stress faced by the PWC.

> Difficult... no doubt about it ... but his is the only way we will

> ever learn anything about cortisol and CFS. WE also believe that

> exercise stress testing cortisol levels is a gaint leap forward for

> CFS care. We pray that a few doctors might read these words and

that

> realility might sink in and maybe we can get some really valuable

> research done and quit wasting time and money on stupid science.

>

> Anyway, I guess I do sound a bit like a know it all when compared

to

> the other idiots working in the same area of research. hummm,

maybe

> I do know more than any one lese on the planet about boosting

> cortisol in CFS at this point in time?

>

> Dave

>

>

>

>

> > May I ask what makes you the only person on the planet that has

all

> the answers about CFS? I'm sorry to be rude, but you act as if you

> know how this works, nobody knows exactly how this works. Plenty

of

> PWC's say that low dose corisol in various forms works for them.

> Also many doctors and scientists say that all the evidence you are

> talking about concerning hydrocortisone was based on studies of

doses

> much higher than are used now and that true low dose does not

> suppress adrenals.

> >

> > I am glad to hear both sides, it is good to keep us on our toes.

> It sounds like some people get improvement and some get worse. And

> the B6 warning is good. So I apologize if I sound too harsh. But

> there is so much evidence contrary to what you are saying that if

you

> are going to state your case as fact I would like the references to

> review.

> > Thanks,

> > Doris

> > ----- Original Message -----

> > From: D

> > Your failure is to be expected since there is no scientific or

> > medical validity behind low dose hydrocortisone. The HPA axis

> simply

> > resets your own production and you are back to level zero

within

> a

> > day or so. ...

> > Again... there is no validity to the science behind the low

dose

> > hydrocortione. CFS is an illness wherein the H/P/A fails to

> respond

> > to stress. CFS is not an illness of low cortisol under

> conditions of

> > no stress... STRESS is the key to understanding the failure of

> the

> > adrenal glands in CFS. Unless the stress-factor is inserted

into

> > your treatment protocol -- failure is assured.

> >

> >

[Guest guest]

Don,

Yes, I agree... there's lot of reason we can crash including other

adrenal hormones... until we get a hell of a lot more folks trying

something similar to every third day protocol, we are likely to never

find out. What is desperately needed in more trials and more

feedback. Thanks for your comments.

Dave

> > > May I ask what makes you the only person on the planet that has

> all

> > the answers about CFS? I'm sorry to be rude, but you act as if

you

> > know how this works, nobody knows exactly how this works. Plenty

> of

> > PWC's say that low dose corisol in various forms works for them.

> > Also many doctors and scientists say that all the evidence you

are

> > talking about concerning hydrocortisone was based on studies of

> doses

> > much higher than are used now and that true low dose does not

> > suppress adrenals.

> > >

> > > I am glad to hear both sides, it is good to keep us on our

toes.

> > It sounds like some people get improvement and some get worse.

And

> > the B6 warning is good. So I apologize if I sound too harsh.

But

> > there is so much evidence contrary to what you are saying that if

> you

> > are going to state your case as fact I would like the references

to

> > review.

> > > Thanks,

> > > Doris

> > > ----- Original Message -----

> > > From: D

> > > Your failure is to be expected since there is no scientific

or

> > > medical validity behind low dose hydrocortisone. The HPA

axis

> > simply

> > > resets your own production and you are back to level zero

> within

> > a

> > > day or so. ...

> > > Again... there is no validity to the science behind the low

> dose

> > > hydrocortione. CFS is an illness wherein the H/P/A fails to

> > respond

> > > to stress. CFS is not an illness of low cortisol under

> > conditions of

> > > no stress... STRESS is the key to understanding the failure

of

> > the

> > > adrenal glands in CFS. Unless the stress-factor is inserted

> into

> > > your treatment protocol -- failure is assured.

> > >

> > >

[Guest guest]

Don,

If you think you crashed because your adrenals could not produce the

other hormones, then wont high dose ACE help in this situation?

I am just brain storming here. I wanted to try Dave's ETD, started

with Baschetti licorice and my flu symptoms bothered me again. So

backed off on the ETD protocol.

And if I get to do ETD, I want to add ACE too, since I want more

support for adrenals.

Let me know what you think of adding ACE to the ETD protocol.

Thanks,

gayathri.

> However, cortisol in not the only hormone that may be deficient in

> CFS patients. One study, referenced on your own site, found that

> patients with CFS have adrenals 50% or smaller than a normal

control

> group. If our adrenals can't produce enough cortisol because of

this

> problem, then it likely that our adrenals can't produce enough of

the

> other 80 odd hormones they are responsible for making and secreting.

>

> Chief among these hormones is epinephrine (adrenaline). If this is

> the case, then taking hydrocortisone may actually deplete the

ability

> of our adrenals to make other hormones, especially epinephrine.

> Epinephrine is also crucial in maintaining adequate blood pressure

> levels, especially upon standing from a prone position. As you

also

> know, I crashed on the ETD protocol this summer and now suspect

this

> is what happened to me. I may have run my adrenals into the ground

> trying to produce sufficient epinephrine (and other key hormones)

to

> keep up with higher exercise and activity levels, made possible by

> the hydrocortisone supplements.

>

> - don

[Guest guest]

Regarding crashes, especially of the sort you describe, I think they are

inevitable as long as we keep prodding the body to manifest energy it no longer

can really manage to do on its own. Except maybe if we do it extraordinarily

carefully. And well grounded perhaps, as Rich never tires of telling us, on

something that doesn't really stimulate, but nourishes, i.e. glutathione.

I recently suffered a setback from just a few weeks on homeopathic growth

hormone, no less. That was one way to discover my immunity was not as balanced

as I thought. (Couldn't afford testing. Back, now, to the drawing board-but boy,

do those GH pills call to me! I love the energy!)

I know of a variety of ways to pump myself up- and I will crash from every one

of them. And I have noted too, that when I feel more energetic a number of other

symptoms abate; for me that is cognitive, digestive, and joint and muscle pain.

Since we haven't gotten a grip on where it all starts we are always just

treating symptoms, after all-pushing the stone up the hill.

I personally walk a daily tightrope; how much can I get away with doing? Is it a

doing day,(usually when I have caregivers), or is it a recover- from-doing day?

And I juggle my uppers. I don't seem to get such intense side effects with

variety.

But I am often stressed and crabby and irritated-on my doing days. And I am

often sad on my silent days.

The one thing I can say is I keep raising the tightrope a little bit higher off

the ground. But that is never going to equal well. Taking six zillion pills,

potions, and powders,not to mention shots, sweats, zappers, and what have you is

a sure sign something is wrong. Caution is never amiss.

Peace,

Adrienne

Re: Zippy/ cortef Doris Brown

Dave,

As you know, for two months this summer I had good results using your

ETD protocol. It makes a lot more sense than everyday low dosages of

hydrocortisone because of the HPA feedback mechanism. You are quite

right that with daily dosages the body adjusts and you end up back

where you started, which is why so many studies indicate that daily

low dosages of hydrocortisone don't help patients with CFS.

However, cortisol in not the only hormone that may be deficient in

CFS patients. One study, referenced on your own site, found that

patients with CFS have adrenals 50% or smaller than a normal control

group. If our adrenals can't produce enough cortisol because of this

problem, then it likely that our adrenals can't produce enough of the

other 80 odd hormones they are responsible for making and secreting.

Chief among these hormones is epinephrine (adrenaline). If this is

the case, then taking hydrocortisone may actually deplete the ability

of our adrenals to make other hormones, especially epinephrine.

Epinephrine is also crucial in maintaining adequate blood pressure

levels, especially upon standing from a prone position. As you also

know, I crashed on the ETD protocol this summer and now suspect this

is what happened to me. I may have run my adrenals into the ground

trying to produce sufficient epinephrine (and other key hormones) to

keep up with higher exercise and activity levels, made possible by

the hydrocortisone supplements.

-

[Guest guest]

Chief among these hormones is epinephrine (adrenaline). If this is

> the case, then taking hydrocortisone may actually deplete the

ability

> of our adrenals to make other hormones, especially epinephrine.

> Epinephrine is also crucial in maintaining adequate blood pressure

> levels, especially upon standing from a prone position. As you

also

> know, I crashed on the ETD protocol this summer and now suspect

this

> is what happened to me. I may have run my adrenals into the

ground

> trying to produce sufficient epinephrine (and other key hormones)

to

> keep up with higher exercise and activity levels, made possible by

> the hydrocortisone supplements.

>

> - don

Don

I don't think you are correct about epinephrise (adrenaline) raising

the bp, I believe it is aldosterone that does this. It sorts out the

potassium/sodium balance. This is secreted by a different part of

the adrenals, it is the outer cortex that secretes cortisol. This

is the reason why some people need a mineral corticoid to supplement

the aldosterone if it isn't functioning properly, it helps to raise

blood pressure and should stop if falling on exercise.

For myself although I don't produce enough cortisol I have no

problems producing enough adrenaline, in fact I reckon my body has

been running on adrenaline for probably many years whilst the

cortisol mechanism was going very wrong probably because of being

mercury poisoned. It is possible that in some people with CFS that

only some of the enzyme receptors are blocked and maybe it is not

necessarily that the adrenals have shrunk. Only a scan would prove

this of course. Anybody who experiences a lot of anxiety or panic

attacks certainly has enough adrenaline and wouldn't want anymore.

It is a horrible and frightening experience to have too much

adrenaline and not enough cortisol.

Since supplementing first with hydrocortisone and now with

Prednisone I don't have a problem with too much adrenaline and

couldn't have a panic attack how ever hard I tried! Before they

happened nearly every day I went out walking with my dog (even

though I enjoyed walking my dog) - and to think I used to think it

was psychological because that is what most doctors think!!

Pam

[Guest guest]

Gayathri,

During the two months I was on the ETD protocol, I also struggled

with flu-like symptoms. Not surprising, given that cortisol

suppresses your immune system. I found that taking the late Dr.

Poesnecker's immune building supplements helped quite a bit with the

problem.

I tried taking ACE before and after the crash this summer. It helped

a bit, but not much. The problem, I think, might be that ACE doesn't

include much, if any, epinephrine. But it's hard to say, since the

manufacturers of ACE tend not list specifics and only say that ACE

contains a collection of adrenal hormones. ACE obviously doesn't

contain much cortisol, or I would be able to feel the effect the way

I do with hydrocortisone.

- don

> > However, cortisol in not the only hormone that may be deficient

in

> > CFS patients. One study, referenced on your own site, found that

> > patients with CFS have adrenals 50% or smaller than a normal

> control

> > group. If our adrenals can't produce enough cortisol because of

> this

> > problem, then it likely that our adrenals can't produce enough of

> the

> > other 80 odd hormones they are responsible for making and

secreting.

> >

> > Chief among these hormones is epinephrine (adrenaline). If this

is

> > the case, then taking hydrocortisone may actually deplete the

> ability

> > of our adrenals to make other hormones, especially epinephrine.

> > Epinephrine is also crucial in maintaining adequate blood

pressure

> > levels, especially upon standing from a prone position. As you

> also

> > know, I crashed on the ETD protocol this summer and now suspect

> this

> > is what happened to me. I may have run my adrenals into the

ground

> > trying to produce sufficient epinephrine (and other key hormones)

> to

> > keep up with higher exercise and activity levels, made possible

by

> > the hydrocortisone supplements.

> >

> > - don

[Guest guest]

Adrienne,

Your description below fits me exactly. A high-wire act, never

knowing when that extra few minutes of activity may be one-step too

far. I have also found numerous things that give me " false " energy

and that mixing them and using them sparingly reduces the chance of a

crash.

Amino acid therapy to build our immune systems definitely fits into

the " nourishing " category. But, while it helps with my immune

system, it does little for my low blood pressure and other symptoms

like chest pains. This disease is truly a three legged stool,

requiring immune, hormonal, and neurological support. My next leg is

neurological. I will be seeing a cardiologist shortly to determine

if I have Neurally Mediated Hypotension (NMH).

I have all the clinical symptoms (e.g., low BP upon standing, dizzy,

etc.). However, as I understand the pathology of NMH, it involves

some kind of disruption in signals from the brain to the adrenals,

resulting in insufficient adrenaline secretions during exercise and

standing (--hence, the standard tilt table test). Here is the rub I

see, if your adrenals are exhausted, then using beta blockers or

other means to push your adrenals to release more epinephrine will

probably result in a crash. I will keep you posted.

- don

> Regarding crashes, especially of the sort you describe, I think

they are inevitable as long as we keep prodding the body to manifest

energy it no longer can really manage to do on its own. Except maybe

if we do it extraordinarily carefully. And well grounded perhaps, as

Rich never tires of telling us, on something that doesn't really

stimulate, but nourishes, i.e. glutathione.

>

> I recently suffered a setback from just a few weeks on homeopathic

growth hormone, no less. That was one way to discover my immunity was

not as balanced as I thought. (Couldn't afford testing. Back, now, to

the drawing board-but boy, do those GH pills call to me! I love the

energy!)

>

> I know of a variety of ways to pump myself up- and I will crash

from every one of them. And I have noted too, that when I feel more

energetic a number of other symptoms abate; for me that is cognitive,

digestive, and joint and muscle pain.

> Since we haven't gotten a grip on where it all starts we are always

just treating symptoms, after all-pushing the stone up the hill.

> I personally walk a daily tightrope; how much can I get away with

doing? Is it a doing day,(usually when I have caregivers), or is it a

recover- from-doing day? And I juggle my uppers. I don't seem to get

such intense side effects with variety.

>

> But I am often stressed and crabby and irritated-on my doing days.

And I am often sad on my silent days.

> The one thing I can say is I keep raising the tightrope a little

bit higher off the ground. But that is never going to equal well.

Taking six zillion pills, potions, and powders,not to mention shots,

sweats, zappers, and what have you is a sure sign something is wrong.

Caution is never amiss.

> Peace,

> Adrienne

>

>

>

>

>

>

> Re: Zippy/ cortef Doris Brown

>

>

> Dave,

>

> As you know, for two months this summer I had good results using

your

> ETD protocol. It makes a lot more sense than everyday low

dosages of

> hydrocortisone because of the HPA feedback mechanism. You are

quite

> right that with daily dosages the body adjusts and you end up

back

> where you started, which is why so many studies indicate that

daily

> low dosages of hydrocortisone don't help patients with CFS.

>

> However, cortisol in not the only hormone that may be deficient

in

> CFS patients. One study, referenced on your own site, found that

> patients with CFS have adrenals 50% or smaller than a normal

control

> group. If our adrenals can't produce enough cortisol because of

this

> problem, then it likely that our adrenals can't produce enough of

the

> other 80 odd hormones they are responsible for making and

secreting.

>

> Chief among these hormones is epinephrine (adrenaline). If this

is

> the case, then taking hydrocortisone may actually deplete the

ability

> of our adrenals to make other hormones, especially epinephrine.

> Epinephrine is also crucial in maintaining adequate blood

pressure

> levels, especially upon standing from a prone position. As you

also

> know, I crashed on the ETD protocol this summer and now suspect

this

> is what happened to me. I may have run my adrenals into the

ground

> trying to produce sufficient epinephrine (and other key hormones)

to

> keep up with higher exercise and activity levels, made possible

by

> the hydrocortisone supplements.

>

> -

>

>

[Guest guest]

Pam,

You are right that aldosterone also helps with blood pressure. I

took Flornif two years ago and for a bit felt great, then the big

crash came, adding chest pain to list of my symptoms.

But in addition to cortisol and aldosterone, epinephrine also helps

maintain blood pressure upon standing, sitting up, and other

activities. Blood pools in the legs when you stand from a prone

position and normally your brain signals the adrenals to supply

epinephrine to get the heart pumping harder to move the blood out of

your legs. However, with Neurally Mediated Hypotension (NMH), the

signal from the brain to the adrenals doesn't happen properly, so

your BP remains low and you feel dizzy. At least that is the current

theory.

- don

> Chief among these hormones is epinephrine (adrenaline). If this

is

> > the case, then taking hydrocortisone may actually deplete the

> ability

> > of our adrenals to make other hormones, especially epinephrine.

> > Epinephrine is also crucial in maintaining adequate blood

pressure

> > levels, especially upon standing from a prone position. As you

> also

> > know, I crashed on the ETD protocol this summer and now suspect

> this

> > is what happened to me. I may have run my adrenals into the

> ground

> > trying to produce sufficient epinephrine (and other key hormones)

> to

> > keep up with higher exercise and activity levels, made possible

by

> > the hydrocortisone supplements.

> >

> > - don

>

> Don

>

> I don't think you are correct about epinephrise (adrenaline)

raising

> the bp, I believe it is aldosterone that does this. It sorts out

the

> potassium/sodium balance. This is secreted by a different part of

> the adrenals, it is the outer cortex that secretes cortisol. This

> is the reason why some people need a mineral corticoid to

supplement

> the aldosterone if it isn't functioning properly, it helps to raise

> blood pressure and should stop if falling on exercise.

>

> For myself although I don't produce enough cortisol I have no

> problems producing enough adrenaline, in fact I reckon my body has

> been running on adrenaline for probably many years whilst the

> cortisol mechanism was going very wrong probably because of being

> mercury poisoned. It is possible that in some people with CFS that

> only some of the enzyme receptors are blocked and maybe it is not

> necessarily that the adrenals have shrunk. Only a scan would prove

> this of course. Anybody who experiences a lot of anxiety or panic

> attacks certainly has enough adrenaline and wouldn't want anymore.

> It is a horrible and frightening experience to have too much

> adrenaline and not enough cortisol.

>

> Since supplementing first with hydrocortisone and now with

> Prednisone I don't have a problem with too much adrenaline and

> couldn't have a panic attack how ever hard I tried! Before they

> happened nearly every day I went out walking with my dog (even

> though I enjoyed walking my dog) - and to think I used to think it

> was psychological because that is what most doctors think!!

>

> Pam

[Guest guest]

Thanks for the response Dave. Although I'm not sure yet what to make of it.

How do you explain all the people who say it helps? Placebo?

Doris

[Guest guest]

Doris,

I know this question is directed at Dave, but from my review of the

medical literature, I can tell you that some studies show taking a

daily low dosage of hydrocortisone can result in improvement.

However, these studies are short term. Longer term studies have

found the effect doesn't last because of HPA feedback adjustment.

And many studies show no positive results from daily low dosage

therapy, even with coupled with Flornef.

- don

> Thanks for the response Dave. Although I'm not sure yet what to

make of it. How do you explain all the people who say it helps?

Placebo?

> Doris

>

>