Autism & Vitiligo

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Vitiligo

“Tryptophan metabolism in vitiligo: An activity of tryptophan

pyrrolase was not observed in

skin of healthy persons and of patients with vitiligo. Content of

serotonin was similar in skin

of normal persons and in skin of patients with normal pigmentation

and in depigmented area.

But content of serotonin in blood and excretion of anthranilic

acid were decreased in the

patients as compared with healthy persons. Excretion of

kynurenine, 3-hydroxykynurenine,

3-hydroxyanthranilic acid, kynureninic, xanthurenic and

5-hydroxyindolyl acetic acids was

increased in patients and this increase was more distinct after

loading with 1-tryptophan. The

data obtained suggest that kynurenine and serotonin pathways of

tryptophan metabolism

were intensified in vitiligo.” Tryptophan metabolism in vitiligo;

Kurbanov, Kh.; Berezov, T.T.;

Vopr. Med. Khim. 1976 Sep, 22:5, 683-7.

Autism

“Based on data including urinary serotonin and

5-hydroxyindoleacetic acid, platelet serotonin

uptake and efflux, platelet monoamine oxidase and glutathione

peroxidase activities, and uric

acid and plasma tryptophan, the origin(s) of such hyperserotonemia

in autism appear(s) to be

of metabolic origin, i.e., a decreased catabolism and/or an

increased biosynthesis of

serotonin.” Serotonin metabolism and other biochemical

parameters in infantile autism. A

controlled study of 22 autistic children; Launay, J.M., Ferrari,

P., Haimart, M., Bursztejn, C.,

Tabuteau, F., Braconnier, A., Pasques-Bondoux, D., Luong, C.,

Dreux, C.; Service de Biochimie et

Neuroendocrinologie, Hôpital Saint-Louis, Paris, France;

Neuropsychobiology, 1988, 20:1, 1-11.

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Sara's Diet - a comprehensive dietary approach to autism

http://personal.atl.bellsouth.net/~sojmed/sara's-diet.html