Guest guest Posted September 12, 2002 Report Share Posted September 12, 2002 I have to read more on the breathing technique, but I know when I take some deep breaths, not quite but almost hyperventilating, that I feel a warmness (and I assume oxygen}, spread to my hands and feet, which often are cold and blue-ish. My sense has been it is of help. Jim Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2002 Report Share Posted September 12, 2002 Rich, That's right, Cheney's theory was to simulate what athletes do - train at high altitude so the body becomes more efficient with oxygen delivery, right? Do you mean 2,3 DPG {not BPG}? That's not measurable yet for the public, is it? I think the deep breathing, causing that warm feeling, is helpful. Not positive. Being an ex-athlete, we would try to saturate the bloodstream w/ oxygen just before a race, so that's kind of what I'm doing, especially before I exert, since I go anaerobic very quickly {which I think is much more than just deconditioning}. My CO2 level once was high, several other times normal. I definitely have circulatory problems {when I'm not doing well} - high rest heart rate, cold extremeties, purplish extremeties, brain fog {which is alleviated when I lie down, getting more blood to the brain}. No lung disease, no major heart trouble {some PVC's, mitrovalve prolapse, minor murmur}. It seems to be like what happens to people when they get the flu - cold extremeties. Does anyone know why that is? Jim Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2002 Report Share Posted September 12, 2002 > I have to read more on the breathing technique, but I know when I take some > deep breaths, not quite but almost hyperventilating, that I feel a warmness > (and I assume oxygen}, spread to my hands and feet, which often are cold and > blue-ish. My sense has been it is of help. > > Jim Jim, That's interesting. I think it means that in your case not enough oxygen is being transported to your capillaries. When you take deep breaths, you put more oxygen into your arterial blood and you lower the carbon dioxide level. Lowering the carbon dioxide level actually causes the oxygen to be bound more tightly to the hemoglobin. If this type of breathing helps you, it suggests that the thing limiting oxygen transport to your tissues is not too little carbon dioxide in the blood, leading to too alkaline blood and too tight binding of oxygen to hemoglobin, but too little oxygen in the blood. Do you have a history of lung disease? How about heart disease? Have you had your total red blood cell mass measured? Do you have evidence of hypercoagulation, such as very low sed rate or other specialized coagulation tests such as ISAC? Taking deep breaths, almost hyperventilating, does the opposite of what the Weil breathing exercise, advocated by Dr. Cheney, does. In that exercise, the person holds their breath, lowering the oxygen level in the arterial blood and raising the carbon dioxide level. The idea is that this will cause the red blood cells to produce more 2,3 BPG over time, which will cause the hemoglobin to release oxygen to the tissues more easily. This helps many PWCs, because the thing limiting oxygen supply to their tissues is low carbon dioxide, leading to too alkaline blood and tight binding of oxygen to their hemoglobin. I think this is another example of PWCs being in different subsets. Rich Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2002 Report Share Posted September 12, 2002 > Rich, > > That's right, Cheney's theory was to simulate what athletes do - train at > high altitude so the body becomes more efficient with oxygen delivery, right? > > Do you mean 2,3 DPG {not BPG}? That's not measurable yet for the public, is > it? > > I think the deep breathing, causing that warm feeling, is helpful. Not > positive. Being an ex-athlete, we would try to saturate the bloodstream w/ > oxygen just before a race, so that's kind of what I'm doing, especially > before I exert, since I go anaerobic very quickly {which I think is much more > than just deconditioning}. > > My CO2 level once was high, several other times normal. I definitely have > circulatory problems {when I'm not doing well} - high rest heart rate, cold > extremeties, purplish extremeties, brain fog {which is alleviated when I lie > down, getting more blood to the brain}. > > No lung disease, no major heart trouble {some PVC's, mitrovalve prolapse, > minor murmur}. It seems to be like what happens to people when they get the > flu - cold extremeties. Does anyone know why that is? > > Jim Jim, 2,3 BPG is the new name for the same substance. The D stands for " di- " m while the B stands for " bi- " . Big deal, huh? I think some labs do measure it. It's in my new lab & diagnostic tests manual. The sample has to be iced and analyzed right away, because 2,3 BPG doesn't hang around long. Cold extremities mean that the metabolic rate in the peripheral tissues, including the skeletal muscles is low, so the cells aren't generating as much heat as normal. Various things can cause this. When a normal, healthy person catches the flu, I suspect it's caused by the immune system grabbing the glutathione precursors in order to go after the viruses, so that the muscles don't get their usual supply. This puts partial blockades into their Krebs cycles and slows their metabolic rate. It would be interesting to know how you would do on oxygen treatment. If you improved, that would be more evidence that your metabolic rate is being limited by oxygen transport to your tissues. Rich Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2002 Report Share Posted September 12, 2002 rvankonynen wrote: > Taking deep breaths, almost hyperventilating, does the opposite of > what the Weil breathing exercise, advocated by Dr. Cheney, does. In > that exercise, the person holds their breath, lowering the oxygen > level in the arterial blood and raising the carbon dioxide level. > The idea is that this will cause the red blood cells to produce more > 2,3 BPG over time, which will cause the hemoglobin to release oxygen > to the tissues more easily. This helps many PWCs, because the thing > limiting oxygen supply to their tissues is low carbon dioxide, > leading to too alkaline blood and tight binding of oxygen to their > hemoglobin. > I wonder if there's a correlation... Some diets (e.g. macrobiotic) criticize meat-heavy diets as producing too acidic blood. I know that the macrobiotic diet made me really sick after I got CFIDS, and that my body absolutely craves animal protein, in large amounts, on a regular basis. So if I'm eating lots of meat etc and making my blood more acidic, would this tend to counteract the alkaline blood condition you describe, loosen the binding of oxygen to hemoglobin, and thereby increase the ability to get oxygen to the muscles and other tissues? -- el (andrea@...) Nevada City, CA, USA " ...wake now! Discover that you are the song that the morning brings... " " One is taught by experience to put a premium on those few people who can appreciate you for what you are. " - Gail Godwin Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2002 Report Share Posted September 12, 2002 > > > Taking deep breaths, almost hyperventilating, does the opposite of > > what the Weil breathing exercise, advocated by Dr. Cheney, does. In > > that exercise, the person holds their breath, lowering the oxygen > > level in the arterial blood and raising the carbon dioxide level. > > The idea is that this will cause the red blood cells to produce more > > 2,3 BPG over time, which will cause the hemoglobin to release oxygen > > to the tissues more easily. This helps many PWCs, because the thing > > limiting oxygen supply to their tissues is low carbon dioxide, > > leading to too alkaline blood and tight binding of oxygen to their > > hemoglobin. > > > > I wonder if there's a correlation... > > Some diets (e.g. macrobiotic) criticize meat-heavy diets as producing too acidic blood. I know that the macrobiotic diet made me really sick after I got CFIDS, and that my body absolutely craves > animal protein, in large amounts, on a regular basis. > > So if I'm eating lots of meat etc and making my blood more acidic, would this tend to counteract the alkaline blood condition you describe, loosen the binding of oxygen to hemoglobin, and thereby > increase the ability to get oxygen to the muscles and other tissues? , As far as I know, meat-heavy diets do not have a significant effect on the pH of the blood, which continues to be controlled in a fairly tight window by the kidneys and the lungs. Meat-heavy diets definitely acidify the urine, because the kidneys move the urine pH around wherever they need to to control the blood pH fairly tightly. I suspect that the reason your body does better on a meat-heavy diet is that you have partial blockades early in the Krebs cycles of your red, " slow-twitch " skeletal muscle cells, and probably in some other types of cells as well, such as neurons. Because of this, these cells are not able to utilize carbohydrates and fats as well as normal, because these fuels must enter at the top of the Krebs cycles as acetyl Co-A. Protein, on the other hand, is broken up into amino acids. Some of these can be interconverted into each other by transamination reactions, and some of them can enter the Krebs cycles beyond the point where the blockades are located. Protein is thus a much more flexible fuel. The result is that you can utilize protein as a fuel for making ATP better than you can utilize carbohydrates and fats. If you eat much of these latter two, much of them will be converted to stored fat, because they cannot be burned at a very high rate. this will be a very stubborn weight gain, because the skeletal muscle cells cannot burn fat well in your case. These problems will be present until the blockades are removed. In my view, eating a high-meat diet is a good thing to do in the meantime, but the strategic thing is to figure out how to remove the partial blockades. For many PWCs, I think the answer for doing this is to manage to replenish the glutathione. By the way, the fact that you do better on meat says that the problem is in early part of the Krebs cycles and not in the respiratory chains. Some PWCs don't benefit much from high-meat diets, because their problem is in the respiratory chains, or at the bottom of the chains, where oxygen is required as the final electron acceptor. If they have a problem getting oxygen to the cells, for example because their lungs are not putting enough oxygen into the blood, or because the heart has difficulty pumping the blood at a sufficient rate, or because there aren't enough total red blood cells, high-meat diets won't help them. This is one way to diagnose where the problem lies. Rich Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 2002 Report Share Posted September 13, 2002 Is there anything magical about the " 7 " in this one, or do you think 4-8-8 would work as well? The reason I ask is that my > mind/body has a much easier time keeping its place in the latter, and I don't have to think so hard ;@) > > > -- > > el (andrea@o...) Nevada City, CA, USA =============================================================== I too was wondering about this. To simplify things for me. I have been just holding my breath until I feel the first urge to breath (usually around 20 counts). On the last two breaths, I try to go for as long as I can holding my breath. I have found that if I try to hold my breath for too long, other than the last two, I run out of oxygen, get out of rhythm, and have to stop. It just seemed reasonable to me that, if holding your breath was the objective, then the more the better. But, I may be wrong. So far, so good. Though, I haven't noticed any difference in my well being from this exercise in 2 months. What is interesting is the changes in my ability to hold my breath. On days when I feel better, I can go up to 30 or more counts consistently. On days when I feel rotten, I can hardly go for 15 counts. Seems like this difference would be significant from a research standpoint? Best, Zippy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 2002 Report Share Posted September 13, 2002 > > > I suspect that the reason your body does better on a meat-heavy diet > > is that you have partial blockades early in the Krebs cycles of your > > red, " slow-twitch " skeletal muscle cells, and probably in some other > > types of cells as well, such as neurons. Because of this, these > > cells are not able to utilize carbohydrates and fats as well as > > normal, because these fuels must enter at the top of the Krebs cycles > > as acetyl Co-A. Protein, on the other hand, is broken up into amino > > acids. Some of these can be interconverted into each other by > > transamination reactions, and some of them can enter the Krebs cycles > > beyond the point where the blockades are located. Protein is thus a > > much more flexible fuel. The result is that you can utilize protein > > as a fuel for making ATP better than you can utilize carbohydrates > > and fats. If you eat much of these latter two, much of them will be > > converted to stored fat, because they cannot be burned at a very high > > rate. this will be a very stubborn weight gain, because the skeletal > > muscle cells cannot burn fat well in your case. > > Boy, did you hit that one on the head! (Do you have a secret spy- cam installed in my house? :@) > > > These problems will > > be present until the blockades are removed. In my view, eating a > > high-meat diet is a good thing to do in the meantime, but the > > strategic thing is to figure out how to remove the partial > > blockades. For many PWCs, I think the answer for doing this is to > > manage to replenish the glutathione. > > Sounds like I should go back to doing the whey, then! Any other suggestions for removing the blockages? Does N-acetyl-cysteine (sp?) work for this? > > > > -- > > el (andrea@o...) Nevada City, CA, USA > " ...wake now! Discover that you are the song > that the morning brings... " > > " One is taught by experience to put a premium > on those few people who can appreciate you > for what you are. " - Gail Godwin , Nope, no secret spy-cams! Just the inexhorable logic of biochemistry, hopefully correctly applied! Yes, NAC together with a good high-protein diet will work, but it's important to keep the amount of NAC down to 300 mg per day if you think you might have much mercury in your body, according to Dr. Quig of Doctor's Data Labs in Chicago. If you can handle nondenatured whey protein, such as ImmunePro RX, I think that's the best way to go. Again, mercury is an issue, so you need to assure yourself that it isn't high, either because you don't have silver amalgam fillings and haven't eaten much large predatory types of fish, or because you have been tested and found that it's low. Rich Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 13, 2002 Report Share Posted September 13, 2002 I think 4/8/8 is fine, but I don't think just holding your breath does the same thing. This is just based on experimentation. Thanks, Doris ----- Original Message ----- From: " bhp355 " <zippy890@...> > Is there anything magical about the " 7 " in this one, or do you think > 4-8-8 would work as well? The reason I ask is that my > > mind/body has a much easier time keeping its place in the latter, > and I don't have to think so hard ;@) > > >> =============================================================== > > I too was wondering about this. > > To simplify things for me. I have been just holding my breath until > I feel the first urge to breath (usually around 20 counts). On the > last two breaths, I try to go for as long as I can holding my breath. Quote Link to comment Share on other sites More sharing options...
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