Re: Uric acid--Steve B. and the group

[Guest guest]

My uric acid is also low and my total protein,also.Is there any relationship

between the two? Thanks..

Nil

Uric acid--Steve B. and the group

| Steve and the group,

|

| I think my earlier message on this subject may have gotten lost.

|

| A long time ago we had a discussion on uric acid, and as I recall,

| Steve, you mentioned that yours was low. I think several others said

| theirs was low, also. I've only found one PWC with elevated uric

| acid, and in that case it resulted in gout.

|

| I think I now understand why uric acid is usually low in PWCs. I

| listened to a tape over the weekend by a Bickel, Ph.D. She said

| that uric acid is an antioxidant, and that it is a relatively

| inexpensive indicator of low glutathione. When glutathione is low,

| and thus can't handle the oxidizing free radicals at a normal rate,

| uric acid picks up some of the slack, and it therefore goes low.

|

| So this seems to be consistent with glutathione depletion and a state

| of oxidative stress in CFIDS, for which there is other evidence.

|

| Rich

|

|

|

| This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

|

|

[Guest guest]

Nil,

I don't think there is a direct connection. Do you have

measurements of the different types of protein, i.e. albumin and

the globulins?

Low total protein can be caused by several things, such as

insufficient nutritional intake (starvation or malabsorption),

severe liver disease, alcoholism, kidney disease, diarrhea (as in

Crohn's disease or ulcerative colitis), hypothyroidism and others. To

narrow it down would require more information.

Please view this simply as information, not medical advice.

Rich

> My uric acid is also low and my total protein,also.Is there any

relationship

> between the two? Thanks..

> Nil

> Uric acid--Steve B. and the group

>

>

> | Steve and the group,

> |

> | I think my earlier message on this subject may have gotten lost.

> |

> | A long time ago we had a discussion on uric acid, and as I recall,

> | Steve, you mentioned that yours was low. I think several others

said

> | theirs was low, also. I've only found one PWC with elevated uric

> | acid, and in that case it resulted in gout.

> |

> | I think I now understand why uric acid is usually low in PWCs. I

> | listened to a tape over the weekend by a Bickel, Ph.D. She

said

> | that uric acid is an antioxidant, and that it is a relatively

> | inexpensive indicator of low glutathione. When glutathione is

low,

> | and thus can't handle the oxidizing free radicals at a normal

rate,

> | uric acid picks up some of the slack, and it therefore goes low.

> |

> | So this seems to be consistent with glutathione depletion and a

state

> | of oxidative stress in CFIDS, for which there is other evidence.

> |

> | Rich

> |

> |

> |

> | This list is intended for patients to share personal experiences

with each

> other, not to give medical advice. If you are interested in any

treatment

> discussed here, please consult your doctor.

> |

> |

[Guest guest]

No Rich,

I only had total protein count.Could be malabsorption.Thanks.

Nil

Re: Uric acid--Steve B. and the group

| Nil,

|

[Guest guest]

Steve,

Don't forget the Isoprinosine can also increase uric acid levels.

Jim

[Guest guest]

Rich,

Interesting. I wonder if I had my uric acid re-tested whether it would

still be low given that I've been on whey and other supplements for almost 3

years. Steve B.

>From: " rvankon " <vankonynenburg1@...>

>Reply-

>

>Subject: Uric acid--Steve B. and the group

>Date: Mon, 25 Mar 2002 22:18:03 -0000

>

>Steve and the group,

>

>A long time ago we had a discussion on the list about uric acid. I

>think you said that yours was low, Steve, and several other people

>said the same. I have only found one PWC who has high uric acid,

>which produced gout in his case, but most PWCs seem to have low uric

>acid.

>

>I think I now know why this happens. Over the weekend I listened to a

>tape by a Bickel, Ph.D. She pointed out that uric acid is an

>antioxidant, and low uric acid indicates that there is low

>glutathione, and the body is in a state of oxidative stress. She said

>this is a less expensive way to find out the glutathione status.

>

>So this seems to fit in well with the observation that Dr. Cheney

>first reported of low glutathione in many PWCs.

>

>Rich

>

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[Guest guest]

Steve,

I don't know, but it would be interesting to find out.

Rich

>

> Rich,

>

> Interesting. I wonder if I had my uric acid re-tested whether it

would

> still be low given that I've been on whey and other supplements for

almost 3

> years. Steve B.

>

> >From: " rvankon " <vankonynenburg1@l...>

> >Reply-@y...

> >@y...

> >Subject: Uric acid--Steve B. and the group

> >Date: Mon, 25 Mar 2002 22:18:03 -0000

> >

> >Steve and the group,

> >

> >A long time ago we had a discussion on the list about uric acid. I

> >think you said that yours was low, Steve, and several other people

> >said the same. I have only found one PWC who has high uric acid,

> >which produced gout in his case, but most PWCs seem to have low

uric

> >acid.

> >

> >I think I now know why this happens. Over the weekend I listened

to a

> >tape by a Bickel, Ph.D. She pointed out that uric acid is an

> >antioxidant, and low uric acid indicates that there is low

> >glutathione, and the body is in a state of oxidative stress. She

said

> >this is a less expensive way to find out the glutathione status.

> >

> >So this seems to fit in well with the observation that Dr. Cheney

> >first reported of low glutathione in many PWCs.

> >

> >Rich

> >

>

>

> _________________________________________________________________

> MSN Photos is the easiest way to share and print your photos:

> http://photos.msn.com/support/worldwid

[Guest guest]

Interesting Rich.

This was one of the reasons put forward not to take Vitamin C. You

will recall humans and other primates do not make their own vitamin

C. Some have seen this as an evolutionary defect. And thus we

should take Vitamin C, and lots of it.

Others countered that humans have plenty of uric acid, so we don't

need to take above normal dietary levels of vitamin C. Interesting.

Of course, it has been discussed before here how PWC's with low

glutathione should probably not take mega-doses of vitamin C.

Zippy

==================================================================

> Steve and the group,

>

> A long time ago we had a discussion on the list about uric acid. I

> think you said that yours was low, Steve, and several other people

> said the same. I have only found one PWC who has high uric acid,

> which produced gout in his case, but most PWCs seem to have low

uric

> acid.

>

> I think I now know why this happens. Over the weekend I listened

to a

> tape by a Bickel, Ph.D. She pointed out that uric acid is an

> antioxidant, and low uric acid indicates that there is low

> glutathione, and the body is in a state of oxidative stress. She

said

> this is a less expensive way to find out the glutathione status.

>

> So this seems to fit in well with the observation that Dr. Cheney

> first reported of low glutathione in many PWCs.

>

> Rich

[Guest guest]

" Of course, it has been discussed before here how PWC's with low

glutathione should probably not take mega-doses of vitamin C. "

Sorry,I have missed that discusson. Why,could you please explain?Thanks. Nil

Re: Uric acid--Steve B. and the group

| Interesting Rich.

|

| This was one of the reasons put forward not to take Vitamin C. You

| will recall humans and other primates do not make their own vitamin

| C. Some have seen this as an evolutionary defect. And thus we

| should take Vitamin C, and lots of it.

|

| Others countered that humans have plenty of uric acid, so we don't

| need to take above normal dietary levels of vitamin C. Interesting.

|

| Of course, it has been discussed before here how PWC's with low

| glutathione should probably not take mega-doses of vitamin C.

|

| Zippy

|

|

| ==================================================================

|

|

|

|

| > Steve and the group,

| >

| > A long time ago we had a discussion on the list about uric acid. I

| > think you said that yours was low, Steve, and several other people

| > said the same. I have only found one PWC who has high uric acid,

| > which produced gout in his case, but most PWCs seem to have low

| uric

| > acid.

| >

| > I think I now know why this happens. Over the weekend I listened

| to a

| > tape by a Bickel, Ph.D. She pointed out that uric acid is an

| > antioxidant, and low uric acid indicates that there is low

| > glutathione, and the body is in a state of oxidative stress. She

| said

| > this is a less expensive way to find out the glutathione status.

| >

| > So this seems to fit in well with the observation that Dr. Cheney

| > first reported of low glutathione in many PWCs.

| >

| > Rich

|

|

|

| This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

|

|

[Guest guest]

Hmmmm...I am probably not the best person to answer this. But, I did

bring it up.

Basically, glutathione is at the base of the antioxidant cascade

chain. For example, if you take a lot of vitamin A, it will pass the

oxidative stress to the next step down, which is vitamin E, then down

to vitamin C, then down to either Lipoic Acid, or Glutathione.

Thus, taking a lot of vitamin C (I think it was over 3 grams?) may be

too much of a stress on the glutathione reserves/manufacturing

capapcity of already stressed in this area PWC's.

Did I get that right? I want a (sugar free) sucker if I did.

Zippy

==================================================================

> " Of course, it has been discussed before here how PWC's with low

> glutathione should probably not take mega-doses of vitamin C. "

> Sorry,I have missed that discusson. Why,could you please explain?

Thanks. Nil

==================================================================

>

>

> Re: Uric acid--Steve B. and the group

>

>

> | Interesting Rich.

> |

> | This was one of the reasons put forward not to take Vitamin C.

You

> | will recall humans and other primates do not make their own

vitamin

> | C. Some have seen this as an evolutionary defect. And thus we

> | should take Vitamin C, and lots of it.

> |

> | Others countered that humans have plenty of uric acid, so we don't

> | need to take above normal dietary levels of vitamin C.

Interesting.

> |

> | Of course, it has been discussed before here how PWC's with low

> | glutathione should probably not take mega-doses of vitamin C.

> |

> | Zippy

> |

> |

> | ==================================================================

> |

> |

> |

[Guest guest]

Jim,

Good point. I forgot about that. Steve B.

>From: jschm111@...

>Reply-

>

>Subject: Re: Uric acid--Steve B. and the group

>Date: Sat, 30 Mar 2002 17:55:14 EST

>

>Steve,

>

>Don't forget the Isoprinosine can also increase uric acid levels.

>

>Jim

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