Re: clonazepam (Klonopin, Rivotril)--adverse effects on gut and urinary tract

[Guest guest]

> A question for those who've tried clonazepam, either as the generic or as

> the brand name Klonopin, Rivotril (canada):

>

> Has anyone else noticed clonazepam to be very hard on the gut, poorly

> absorbed? ... Anyone out there having success with any other

> benzos like diazepam, lorazepam, etc.?

>

> Anyone else experience the gut discomfort along with the clonazepam?

> Solutions?

>

> Thanks,

> --

>

> Hud

Hud: I had a lot of gut problems with Klonopin, even with food. I had

to get off it, and went on Ativan (lorazapam). No more gut problems. I

just saw Dr. Cheney, and he says Ativan is the second drug of choice

after Klonopin.

Jackie

P.S. I take 1 1/2 mg at breakfast, 1 mg at lunch, 1 mg at dinner, and

1/2 mg at bedtime, with 2 Valerian (Gaia brand), and am now starting on

magnesium sulfate/taurine shots, per Cheney.

[Guest guest]

on 2/9/02 12:16 AM, francophile1002000 at french10@... wrote:

> Hud: I had a lot of gut problems with Klonopin, even with food. I had

> to get off it, and went on Ativan (lorazapam). No more gut problems. I

> just saw Dr. Cheney, and he says Ativan is the second drug of choice

> after Klonopin.

Jackie,

Thanks a million for the info. That's just the kind of thing I wanted to

hear (i.e. what is considered to be second best to clonazepam by Cheney).

i've taken ativan before, a long time back. As I recall the pills are very

small, unlike clonazepam tablets which are quite large.

> P.S. I take 1 1/2 mg at breakfast, 1 mg at lunch, 1 mg at dinner, and

> 1/2 mg at bedtime, with 2 Valerian (Gaia brand), and am now starting on

> magnesium sulfate/taurine shots, per Cheney.

Strange! You take your biggest dose in the morning! Is that right or was

it a typo?

--

Hud

[Guest guest]

>

> Strange! You take your biggest dose in the morning! Is that right or was

> it a typo?

>

> --

>

> Hud

Not a typo. What I found, was that for me, Ativan increased my energy!

It actually made me feel better. So I increased the morning dosage,

where my energy was lowest. You gotta experiment, to get max sleep

benefit as well.

Jackie

P. S. I forget if I mentioned that I also take 2 Valerian (by Gaia) for

sleep.

[Guest guest]

on 2/14/02 1:02 AM, francophile1002000 at french10@... wrote:

>> Strange! You take your biggest dose in the morning! Is that right or was

>> it a typo?

>>

>> --

>>

>> Hud

>

> Not a typo. What I found, was that for me, Ativan increased my energy!

> It actually made me feel better. So I increased the morning dosage,

> where my energy was lowest. You gotta experiment, to get max sleep

> benefit as well.

>

> Jackie

>

>

> P. S. I forget if I mentioned that I also take 2 Valerian (by Gaia) for

> sleep.

Well that's why I asked instead of just assuming... I know different things

work for different people. But tell me how the ativan compares to any other

benzodiazepines youy may have taken (clonazepam, diazepam, alprazolam...).

I'm going to give Ativan a try instead of the clonazepam b/c of gut

problems.

Hud

[Guest guest]

how does klonopin help in cfs i was taking as needed

for anxiety didnt no it helped with cfs and why? also

has anyone tried provigil can this help?

--- H Ramelan <hudr@...> wrote:

> on 2/14/02 1:02 AM, francophile1002000 at

> french10@... wrote:

>

> >> Strange! You take your biggest dose in the

> morning! Is that right or was

> >> it a typo?

> >>

> >> --

> >>

> >> Hud

> >

> > Not a typo. What I found, was that for me, Ativan

> increased my energy!

> > It actually made me feel better. So I increased

> the morning dosage,

> > where my energy was lowest. You gotta experiment,

> to get max sleep

> > benefit as well.

> >

> > Jackie

> >

> >

> > P. S. I forget if I mentioned that I also take 2

> Valerian (by Gaia) for

> > sleep.

>

> Well that's why I asked instead of just assuming...

> I know different things

> work for different people. But tell me how the

> ativan compares to any other

> benzodiazepines youy may have taken (clonazepam,

> diazepam, alprazolam...).

>

> I'm going to give Ativan a try instead of the

> clonazepam b/c of gut

> problems.

>

> Hud

>

>

>

[Guest guest]

on 2/15/02 3:34 PM, michelle cervera at cuteangel54321@... wrote:

> how does klonopin help in cfs i was taking as needed

> for anxiety didnt no it helped with cfs and why? also

> has anyone tried provigil can this help?

Hi michelle,

low dose klonopin or other benzos help during the day to increase alertness

by reducing the sensitivity of a particular receptor in the brain (the NMDA

receptor) which has been found to be 'hypersensitive' in PWC and is believed

to be a central feature of the pathophysiological process in CFS. YOU CAN

find lots of info about this in past posts.

I've tried modafinil (provigil). Not a good drug in general for PWC, from

what I've read. Not a good drug for many persons with narcolepsy either,

for which it was given FDA approval. But for some it apparently helps to

increase alertness without having the 'motor' stimulant quality of

amphetamine and ritalin type drugs.

modafinil seems to cause bad headaches in a rather large percentage of

users-- far larger than the pharm. company acknowledges in their package

insert.

--

Hud (8 >{D)

hudr@...

[Guest guest]

on 2/15/02 3:34 PM, michelle cervera at cuteangel54321@... wrote:

> how does klonopin help in cfs i was taking as needed

> for anxiety didnt no it helped with cfs and why? also

> has anyone tried provigil can this help?

[Guest guest]

ok so klonopin helps with alterness i thought that is

can make people tired and provigil why is that bad i

tried it for 5 days i seemed more tired but im on

other stuff? should i have noticed somwthing in that

time?

--- H Ramelan <hudr@...> wrote:

> on 2/15/02 3:34 PM, michelle cervera at

> cuteangel54321@... wrote:

>

> > how does klonopin help in cfs i was taking as

> needed

> > for anxiety didnt no it helped with cfs and why?

> also

> > has anyone tried provigil can this help?

>

> Hi michelle,

>

> low dose klonopin or other benzos help during the

> day to increase alertness

> by reducing the sensitivity of a particular receptor

> in the brain (the NMDA

> receptor) which has been found to be

> 'hypersensitive' in PWC and is believed

> to be a central feature of the pathophysiological

> process in CFS. YOU CAN

> find lots of info about this in past posts.

>

> I've tried modafinil (provigil). Not a good drug in

> general for PWC, from

> what I've read. Not a good drug for many persons

> with narcolepsy either,

> for which it was given FDA approval. But for some

> it apparently helps to

> increase alertness without having the 'motor'

> stimulant quality of

> amphetamine and ritalin type drugs.

>

> modafinil seems to cause bad headaches in a rather

> large percentage of

> users-- far larger than the pharm. company

> acknowledges in their package

> insert.

> --

>

> Hud (8 >{D)

>

> hudr@...

>

>

>

>

[Guest guest]

on 2/18/02 6:43 PM, michelle cervera at cuteangel54321@... wrote:

> ok so klonopin helps with alterness i thought that is

> can make people tired and provigil why is that bad i

> tried it for 5 days i seemed more tired but im on

> other stuff? should i have noticed somwthing in that

> time?

provigil increases glutamate activity in the brain I think--exactly the

process believed to underlie the excitatory neurotoxicty in CFIDS. Klonopin

acts pretty much in the opposite manner which helps explain its

neuroprotective effects. you said you may have felt more tired on the

provigil? that would make sense b/c it might cause the nmda receptor to

overfire even more than it does 'normally' in the CFIDS brain.

I think goldstein uses provigil to 'antidote' ketamine, which is an nmda

antagonist (and like klonopin is neuroprotective and also increases

alertness in small doses).

--

Hud (8 >{D)

hudr@...

[Guest guest]

hi

i have tried to get off the cfsfme list 9 times and nothing happens. would u

know another way to do it?

thanks very much.

drew

michelle cervera <cuteangel54321@...> wrote: how does klonopin help in

cfs i was taking as needed

for anxiety didnt no it helped with cfs and why? also

has anyone tried provigil can this help?

--- H Ramelan <hudr@...> wrote:

> on 2/14/02 1:02 AM, francophile1002000 at

> french10@... wrote:

>

> >> Strange! You take your biggest dose in the

> morning! Is that right or was

> >> it a typo?

> >>

> >> --

> >>

> >> Hud

> >

> > Not a typo. What I found, was that for me, Ativan

> increased my energy!

> > It actually made me feel better. So I increased

> the morning dosage,

> > where my energy was lowest. You gotta experiment,

> to get max sleep

> > benefit as well.

> >

> > Jackie

> >

> >

> > P. S. I forget if I mentioned that I also take 2

> Valerian (by Gaia) for

> > sleep.

>

> Well that's why I asked instead of just assuming...

> I know different things

> work for different people. But tell me how the

> ativan compares to any other

> benzodiazepines youy may have taken (clonazepam,

> diazepam, alprazolam...).

>

> I'm going to give Ativan a try instead of the

> clonazepam b/c of gut

> problems.

>

> Hud

>

>

>