Guest guest Posted September 29, 2001 Report Share Posted September 29, 2001 Was reading up a bit on sam-e and found this from an article by a Dr. Podell: " Fortunately, there is a simple, inexpensive way to stimulate the body to make SAMe on its own: a combination of three old fashioned vitamins (folic acid, vitamin B12 and Vitamin B6) together with TMG, another nutritional supplement. " That's certainly easy enough, and I checked the prices for TMG at Needs...very inexpensive, whereas sam-e can get quite exorbitant, depending on dose. I'm just wondering about peoples' experiences with TMG for depression/liver toxicity issues/sleep quality etc. and whether it seems to be effective in lieu of sam-e. Thanks... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 30, 2001 Report Share Posted September 30, 2001 > what is TMG please? Tri methyl glycine (i think?). A methyl donor,and precursor, apparently, to sam-e. Had just been looking around the About site a bit and found the article which cited TMG as an alternative to sam-e: http://www.energywave.com/nightmar.htm The About article on sam-e, which has some links to articles and medline stuff at the end, is at http://chronicfatigue.about.com/library/weekly/aa121599a.htm Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 30, 2001 Report Share Posted September 30, 2001 Hi what is TMG please? > I'm just wondering about peoples' experiences with TMG for > depression/liver toxicity issues/sleep quality etc. and whether it > seems to be effective in lieu of sam-e. I aM Tking Sam-e injections for this condition and it is expensive and very annoyant since it has to be every dy and have besides to pay someone to make the injection, Has this combination you mention to be received in injections or orally?thanks. Would you send th article or the web site were you have read this article ? thanks Elena TMG instead of sam-e? > Was reading up a bit on sam-e and found this from an article by a Dr. > Podell: > > " Fortunately, there is a simple, inexpensive way to stimulate the > body to make SAMe on its own: a combination of three old fashioned > vitamins (folic acid, vitamin B12 and Vitamin B6) together with TMG, > another nutritional supplement. " > > That's certainly easy enough, and I checked the prices for TMG at > Needs...very inexpensive, whereas sam-e can get quite exorbitant, > depending on dose. > > > > > > This list is intended for patients to share personal experiences with each other, not to give medical advice. If you are interested in any treatment discussed here, please consult your doctor. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 30, 2001 Report Share Posted September 30, 2001 Hi Elena and I've been taking SAM-e orally as recommended by my rheumatologist for two years at about 800 to 1200 mg daily in enteric coated tabs. The brand I took also contained the nexeccary B vitamins and was significantly cheaper than most brand. In August at the recommendation of a researcher on another list, I stopped SAM-e and began Betaine HCl which is trimethylglycine (TMG) with hydrochloric acid. Lots of people take it to increase stomach acid not realizing that like SAM-e, it is a methyl donor. The only difference I have found with the Betaine is more stomach acid issues and an increased appetite for fats and sugars. I'm about to try TMG before switching back to another product by the company that I've been getting SAM-e from. The new product is all the SAM-e precursors plus some SAM-e and is about 50% of the price. I had been paying about $21.00 for 60 200mg enteric coated caps of SAM-e. The new precursor product is about $11.00 for 60 tabs. Elena, can you get stuff from the USA? MJH > Subject: RE: TMG instead of sam-e? > > Hi > > what is TMG please? > > > I'm just wondering about peoples' experiences with TMG for > > depression/liver toxicity issues/sleep quality etc. and whether it > > seems to be effective in lieu of sam-e. > > I aM Tking Sam-e injections for this condition and it is expensive and very > annoyant since it has to be every dy and have besides to pay someone to make > the injection, > > Has this combination you mention to be received in injections or > orally?thanks. > > Would you send th article or the web site were you have read this article ? > thanks > Elena > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 30, 2001 Report Share Posted September 30, 2001 Hi Elena, I get my supplements from USA. They send them to me as regular mail but there is always a risk of getting lost. I did not have much problem in that. Only one delivery out of 5-6 deliveries were lost. Take care.. Nil RE: TMG instead of sam-e? | > Elena, can you get stuff from the USA?. | | Thats my main problem | I need desesperately someone who is coming from USA to bring some products, | specially ACIDOPHILUS or some probiotic | I cant get them by the post : It takes a lot of time , the meds get spoiled | at customms office during long weeks and after i have to pay 50 % taxes. | Untill now when somebody travels I ask him to buy me some stuff, nonody is | travelling now.... | If someone int his list knows somebody travelling to south america, | Argentina, pls let me know, tthanks. | Elena | | NIL do you get the prods from Usa without ptobls or do you buythemin your | country.Thnks.take care.elena Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 30, 2001 Report Share Posted September 30, 2001 Hi again. Did a search on TMG and found some insights: " In the liver, TMG transfers one of its three methyl groups to homocysteine, which is then converted into the useful amino acid methionine....NOTE: An inexpensive variety is Betaine HCL which acts as a stomach acidifier and is not practical due to stomach irritation at the doses required to enhance methylation metabolism. " (from http://www.digitalnaturopath.com/treat/T36297.html) Additionally, I find it interesting that TMG brings down homocysteine, as I've read that elevated homocysteine promotes the formation of blood clots. Thanks for your replies! Foxhillers, I'd love to hear about your experience with TMG/Sam-e precursors when you try them, on list or backchannel. >...I stopped > SAM-e and began Betaine HCl which is trimethylglycine (TMG) with hydrochloric > acid. The only difference I have found with the Betaine is more stomach acid > issues and an increased appetite for fats and sugars. > I'm about to try TMG before switching back to another product by the > company that I've been getting SAM-e from. The new product is all the SAM-e > precursors plus some SAM-e and is about 50% of the price. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 1, 2001 Report Share Posted October 1, 2001 > Elena, can you get stuff from the USA?. Thats my main problem I need desesperately someone who is coming from USA to bring some products, specially ACIDOPHILUS or some probiotic I cant get them by the post : It takes a lot of time , the meds get spoiled at customms office during long weeks and after i have to pay 50 % taxes. Untill now when somebody travels I ask him to buy me some stuff, nonody is travelling now.... If someone int his list knows somebody travelling to south america, Argentina, pls let me know, tthanks. Elena NIL do you get the prods from Usa without ptobls or do you buythemin your country.Thnks.take care.elena RE: TMG instead of sam-e? > > > > Hi > > > > what is TMG please? > > > > > I'm just wondering about peoples' experiences with TMG for > > > depression/liver toxicity issues/sleep quality etc. and whether it > > > seems to be effective in lieu of sam-e. > > > > I aM Tking Sam-e injections for this condition and it is expensive and very > > annoyant since it has to be every dy and have besides to pay someone to make > > the injection, > > > > Has this combination you mention to be received in injections or > > orally?thanks. > > > > Would you send th article or the web site were you have read this article ? > > thanks > > Elena > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 17, 2001 Report Share Posted October 17, 2001 <<what is your program for taking Tmg, B12 & B6 to get the same results from taking Same?>> I don't have one...I'd just read that TMG could have the same effects as Sam-e, and posted wondering if anyone had experience with that. I've ordered some TMG and such and plan on experimenting with it a bit myself. Another list member had mentioned a product of Sam-e precursors (though I'm not sure that TMG is a precursor with further reading I've done. It's possible that the methyl-donor action of TMG could be similar though). I think it's a bit of sam-e combined with TMG, b vitamins, etc. with the theory that it could be an inexpensive alternative. Whether that idea applies--we'll see. (hope so). Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 17, 2001 Report Share Posted October 17, 2001 Dear , what is your program for taking Tmg, B12 & B6 to get the same results from taking Same? Thank you, M RV: TMG instead of sam-e? > >> Hi >> >> what is TMG please? >> >> > I'm just wondering about peoples' experiences with TMG for >> > depression/liver toxicity issues/sleep quality etc. and whether it >> > seems to be effective in lieu of sam-e. >> >> I aM Tking Sam-e injections for this condition and it is expensive and >very >> annoyant since it has to be every dy and have besides to pay someone to >make >> the injection, >> >> Has this combination you mention to be received in injections or >> orally?thanks. >> >> Would you send th article or the web site were you have read this article >? >> thanks >> Elena >> >> TMG instead of sam-e? >> >> >> > Was reading up a bit on sam-e and found this from an article by a Dr. >> > Podell: >> > >> > " Fortunately, there is a simple, inexpensive way to stimulate the >> > body to make SAMe on its own: a combination of three old fashioned >> > vitamins (folic acid, vitamin B12 and Vitamin B6) together with TMG, >> > another nutritional supplement. " >> > >> > That's certainly easy enough, and I checked the prices for TMG at >> > Needs...very inexpensive, whereas sam-e can get quite exorbitant, >> > depending on dose. >> > >> > >> > >> > >> > >> > This list is intended for patients to share personal experiences with >each >> other, not to give medical advice. If you are interested in any treatment >> discussed here, please consult your doctor. >> > >> > Quote Link to comment Share on other sites More sharing options...
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