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2-5A pathway

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Reading the AACFS Conf reports, there is mention of

the 2-5A pathway and how its abnormality could affect

energy metabolism and exercise intolerance. In 1994

the Cheney clinic had this blood test done on me and

the results were: 16 in a reference range of 1 - 10

" pICO MOLE " (whatever that means!). The report from

Immunosciences Lab who did the tests says that this is

a key enzyme in the antiviral defense mechanism

and it is not functioning properly and is increased in

people with CFS.

Anyone know anything about this? I just dug it out of

my old files. Is this the same thing as the RNaseL

Pathway?

Would this indicate that a virus is at play here,

causing the irregular 2-5A synthetase? How would one

address this with treatment protocol?

Thanks to anyone who can comment.

Martha

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