Re: fibrinogen, hyper-coagulation and licorice

[Guest guest]

" jane_doe_press " wrote:

>>>> Dave, I don't know about licorice and hypercoagulation - it

doesn't have that effect on me but perhaps I don't take enought or

the right type.<<<<<

Licorice extract is difficult to dose correctly. It requires the

right product and lots of help for a few weeks. Most PWCs who use it

get poor results at first, especially if they are on their own.

>>>>I am really sensitive to anything that raises cortisol, it makes

me feel terrible.<<<<<

Yes, this is normal. What we believe is happening is that, due to

months of low cortisol levels, the cells in the brain of a PWC

upregulate the number of cortisol receptors on the cell's surface in

order to capture as much cortisol as possible. These cells are

cortisol starved and trying to take in as much as they can get.

Then, when you take something the increases cortisol levels, the

extra receptors load up and cause the cell to be super saturated with

cortisol and you feel terrible. We have found that when someone like

yourself begins a program to increase cortisol they must go very

slow. If they overload, they must back off for a day and go again 24

hours later. After about 10 days, the cortisol receptors are

downregulated and one responds normally.

>>>>>But I just want to say that you were the first person I met on

the net, years ago now, that suggested something to me that to this

day works - and you mention it below - when I feel bad, sort of

" toxic-yuck-bad " one dose of aspirin clears this up for a few hours

to days. Thank you. <<<<<<<

Yes, if you really feel lousy, aspirin works like a wonder drug.

Aspirin inhibits nitric oxide (vasodialator) and could be helping by

raising blood pressure. It also thins blood and could be helping by

reducing hypercoagulation. This was why I posted about licorice

extract as an inhibitor of thrombin, which also reduces

hypercoagulation.

Dr Posnecker dose licorice extract every day and I was recommending

it every other day. Every other day gets around the feedback problem

that would only lower cortisol. But Posnecker patients get better

results then those following my protocol so I was beginning to think

that licorice might be doing more than just raising cortisol.

Licorice extract also inhibits complement which is involved in the

immune response. Maybe inhibiting complement would help a PWC feel

better? It sure is an area of research that promises a lot of help to

PWCs. Complement is part of the immune response and plays a big part

in red blood cell health and autoimmune illness.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search & DB=PubMed

We know the immune system in CFS is in overdrive...the big question

is why? And, how can we control it without doing more harm?

I'll post more on complement later.

Dave