Re: Three types of intestinal flora

[Guest guest]

wrote:

>

> It is very early, but this kind of research may help at some point:

>

> ... three types of intestinal bacteria and the promise of tailoring

> treatments to people based upon their type.

>

> http://www.nytimes.com/2011/04/21/science/21gut.html?_r=1 & src=me & ref=science

> <http://www.nytimes.com/2011/04/21/science/21gut.html?_r=1 & src=me & ref=science>

>

It is more correct to say that they found three ecosystems of bacteria,

(not types of bacteria), which they call enterotypes. Each enterotype is

a collection of many types of bacteria. The NYT got that point confused

but placed a correction at the bottom. Each enterotype would be subset

of the human microbiome. Think of it like forests. There different types

of forests and each type can be a collection of many types of trees and

plants, not just one, though often they are known for certain types of

trees that are common in them. Each type of forest is a subtype of the

earth's ecosystem. The microbiome is very interesting and surprising. If

you are interested in it I suggest another NTY article:

How Microbes Defend and Define Us

http://www.nytimes.com/2010/07/13/science/13micro.html

(I find pg. 2 the most interesting.)

It would interesting to see this type of survey done in the esophagus

and in particular the esophagi of achalasia patients to see if there is

any enterotype correlation with achalasia.

notan

[Guest guest]

Hi Notan.

Interesting article in your link. I suspect there's a lot going on with this

line of research.

My first thought on reading the recent, but less detailed, article was that this

might be relevant to us.

My second one is that this may be a game changer in medicine.

Sent from Smrtphone That Lacks Spellchecker

[Guest guest]

wrote:

>

>

> My first thought on reading the recent, but less detailed, article was

> that this might be relevant to us.

>

> My second one is that this may be a game changer in medicine.

>

I have some conditions that have been noticed to have correlations to

certain microbiome states, so I have been watching this. Also, back 10

to 20 years ago a friend of mine asked me what I thought of the use of

predatory bacteria and viruses to attack pathogenic ones in the body,

and why there was so little support for the idea. I had never heard of

the idea before that but I have been noticing it at times since.

Considering what they are discovering about the human microbiome and how

it may relate to a number of conditions and the possibility that the use

of live friendly bacteria and live predators of harmful bacterial and

viruses may help, suggests to me that you may well be right about it

being a game changer.

We search the rain forests, among a relatively limited number of plant

types, for exotic plants that may help, but consider that the oceans

alone have an unimaginable variety of bacteria and viruses and that

doesn't count those in microbiomes that exist only in animals that live

in the oceans. It gets my imagination going, and that is before even

considering the viruses (phages and virophages).

When we learn more about the microbiome and the microbes that live in

us, on us, and allover and in the world, along with how to breed,

crossbreed and engineer bacteria to help us, who knows what we will be

able to do with it. I wouldn't expect much in the next ten years though.

As an example of what may be done check out these abstracts about how

Bdellovibrio bacteriovorus can may possibly be used in the treatment of

periodontitis and maybe some other conditions, See:

Predatory lifestyle of Bdellovibrio bacteriovorus.

http://www.ncbi.nlm.nih.gov/pubmed/19575566

" This capability makes Bdellovibrio a potential therapeutic agent, but

since its discovery in the 1960s it has not been applied in this way. "

Bdellovibrio bacteriovorus attacks Aggregatibacter actinomycetemcomitans.

http://www.ncbi.nlm.nih.gov/pubmed/19278992

" ... suggest a potential for B. bacteriovorus as a living antibiotic for

the prevention and treatment of periodontitis. "

Predation of oral pathogens by Bdellovibrio bacteriovorus 109J.

http://www.ncbi.nlm.nih.gov/pubmed/21214870

For info on virophages, see:

'Virophage' suggests viruses are alive

http://www.nature.com/nature/journal/v454/n7205/full/454677a.html

" A metagenomic study of ocean water has revealed an abundance of genetic

sequences closely related to giant viruses, leading to a suspicion that

they are a common parasite of plankton. These viruses had been missed

for many years, ... "

> Sent from Smrtphone That Lacks Spellchecker

>

Sent from my stupid homebuilt quadcore that has a spellchecker but still

can't get it all right

(What I really need is one that find those missing last letter. Were did

those Ss go?)

notan

[Guest guest]

notan wrote:

>

> It gets my imagination going, and that is before even

> considering the viruses (phages and virophages).

>

Should have included a link to this:

British biotech boasts antibiotic breakthrough

http://www.lifescientist.com.au/article/349461/british_biotech_boasts_antibiotic\

_breakthrough/

" The delivery vehicle is a virus able only to infect bacteria, commonly

known as bacteriophage, but which can be modified to target specific

bacterial strains. "

notan

[Guest guest]

As soon as I decided to post about the recent article on this subject, I knew

Notan was going to notice.

Notan, I'm glad you did and that you provided the links on the topic. It will

take me a while to read and digest them.

Thanks

Dan

Sent from Smrtphone That Lacks Spellchecker

notan ostrich <notan_ostrich@...> wrote:

> wrote:

>>

>>

>> My first thought on reading the recent, but less detailed, article was

>> that this might be relevant to us.

>>

>> My second one is that this may be a game changer in medicine.

>>

>

>I have some conditions that have been noticed to have correlations to

>certain microbiome states, so I have been watching this. Also, back 10

>to 20 years ago a friend of mine asked me what I thought of the use of

>predatory bacteria and viruses to attack pathogenic ones in the body,

>and why there was so little support for the idea. I had never heard of

>the idea before that but I have been noticing it at times since.

>Considering what they are discovering about the human microbiome and how

>it may relate to a number of conditions and the possibility that the use

>of live friendly bacteria and live predators of harmful bacterial and

>viruses may help, suggests to me that you may well be right about it

>being a game changer.

>

>We search the rain forests, among a relatively limited number of plant

>types, for exotic plants that may help, but consider that the oceans

>alone have an unimaginable variety of bacteria and viruses and that

>doesn't count those in microbiomes that exist only in animals that live

>in the oceans. It gets my imagination going, and that is before even

>considering the viruses (phages and virophages).

>

>When we learn more about the microbiome and the microbes that live in

>us, on us, and allover and in the world, along with how to breed,

>crossbreed and engineer bacteria to help us, who knows what we will be

>able to do with it. I wouldn't expect much in the next ten years though.

>

>As an example of what may be done check out these abstracts about how

>Bdellovibrio bacteriovorus can may possibly be used in the treatment of

>periodontitis and maybe some other conditions, See:

>

>Predatory lifestyle of Bdellovibrio bacteriovorus.

>http://www.ncbi.nlm.nih.gov/pubmed/19575566

> " This capability makes Bdellovibrio a potential therapeutic agent, but

>since its discovery in the 1960s it has not been applied in this way. "

>

>Bdellovibrio bacteriovorus attacks Aggregatibacter actinomycetemcomitans.

>http://www.ncbi.nlm.nih.gov/pubmed/19278992

> " ... suggest a potential for B. bacteriovorus as a living antibiotic for

>the prevention and treatment of periodontitis. "

>

>Predation of oral pathogens by Bdellovibrio bacteriovorus 109J.

>http://www.ncbi.nlm.nih.gov/pubmed/21214870

>

>For info on virophages, see:

>

>'Virophage' suggests viruses are alive

>http://www.nature.com/nature/journal/v454/n7205/full/454677a.html

> " A metagenomic study of ocean water has revealed an abundance of genetic

>sequences closely related to giant viruses, leading to a suspicion that

>they are a common parasite of plankton. These viruses had been missed

>for many years, ... "

>

>

>> Sent from Smrtphone That Lacks Spellchecker

>>

>

>Sent from my stupid homebuilt quadcore that has a spellchecker but still

>can't get it all right

>(What I really need is one that find those missing last letter. Were did

>those Ss go?)

>

>notan

>

>

>

>