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Do you by chance have

Dr. s office ph #?

Thx

M.

>

> ,

>

> In response to your question as to what " anastomotic dilatation "

is - it is

> a dilatation at the connection area where they hook up your

stomach to

> wherever your esophagus removal point is. Dr. s in Rochester,

NY

> mentioned this to me as well as a possibility. Basically it's

typically a

> result of too much scar tissue forming. He indicated that the

dilatation is

> very easy compared to what we go through now with dilatations, and

usually

> the people that need them tend to need one or two and then that's

it. He did

> not give me a percentage of how many he sees, but did not see it

as a major

> side effect or risk.

>

> Not to trivialize any of this, but needing one or more anastomotic

> dilatations is the least of our worries if we go through with this

surgery.

>

> in NY

>

>

>

> _____

>

> From: achalasia [mailto:achalasia ]

On Behalf

> Of cynmark24@...

> Sent: Thursday, August 03, 2006 9:36 PM

> achalasia

> Subject: Re: Re: Esophagus Removal Mortality

>

>

>

> n,

>

>

>

> Thank you for digging up the two abstracts on Esophagectomies,

the first

> being Achalasia specific. Along with the others who have posted

here about

> the mortality rates, those of us facing E'ectomies clearly

understand that

> since we are otherwise healthy our odds for success should

naturally be

> better than the overall average.

>

>

>

> This is why it seems strange to me that when Dr. Altorki (the

thoracic

> surgeon) was " selling " me on the surgery, he quoted me a number of

5%

> mortality for the operation knowing full well that I am not one of

his

> cancer patients. Why then, did he not say, that the mortality was

1% for

> healthy achalasia patients. Doesn't make sense. Maybe there is

some kind

> of law or code of ethics here stating that when you tell a patient

the

> mortality stats you must tell them the hospital average, or

national

> average, and you're not permitted to give better statistics if the

patient

> does not fit the usual profile (cancer). Just a thought. Maybe

I'll ask my

> daughter that question.

>

>

>

> He did give me a leak rate of 10% precisely matching the

number you

> quoted in the abstract (below).

>

>

>

> n, it appears to me that this operation is no walk in

the park.

> It is full of places for things to go wrong, that get hidden from

view, such

> as

>

>

>

> " Major complications included anastomotic leak (10%), recurrent

laryngeal

> nerve injury (5%), delayed mediastinal bleeding requiring

thoracotomy (2%),

> and chylothorax (2%). There were 2 hospital deaths (2%) from

respiratory

> insufficiency and sepsis. "

>

>

>

> And then to top it off

>

>

>

> " nearly 50% have required an anastomotic dilatation. "

>

>

>

> Excuse me for a sec, its time that I googled.

>

>

>

> (15 minutes later)

>

> I have to confess, I'm having trouble nailing down exactly what it

means.

> Here is a link for anyone with more patience than I have at the

moment.

>

>

>

>

>

> Anastomotic

> <http://content.karger.com/ProdukteDB/produkte.asp?

Aktion=ShowFulltext & Produ

> ktNr=223996 & Ausgabe=227627 & ArtikelNr=52018#SA2> Complications

after

> Esophagectomy - Karger Publishers

>

>

>

> Whatever it is, its not good and its at 50%.

>

>

>

> If I must have the surgery and there is no reliable alternative,

then I am

> not feeling too good at the moment as to what is in store for me.

>

>

>

> I did not see a mention either of acid reflux, considering what is

going to

> be done with our poor stomachs.

>

>

>

> Clearly a lot of thought must be given in order to make a decision

that we

> can go forward with.

>

>

>

> Good, bad, or otherwise, whoever brings to this Board additional

information

> on esophagectomies, I thank you. I thank you for providing me

and everyone

> else facing this with an additional information giving us a better

> perspective. Many of the articles also contain extensive

bibliographies

> providing even more information.

>

>

>

>

>

>

>

>

>

> In a message dated 8/3/2006 8:37:14 P.M. Eastern Standard Time,

> rnbriely@... writes:

>

> Here are two abstracts on esophagectomies. The first is Achalasia

specific,

> the second is more general. Mortality rates were 2% (n=93patients)

and 4%

> (n=1085 patients) respecitvely. Perhaps another good number to

focus on is

> the 95% of patients in the first study who are eating well after

the

> surgery.

>

> Best wishes to all of you having to make this difficult decision.

>

> Regards,

> n

>

> Abstract #1

> Esophagectomy for achalasia: patient selection and clinical

experience

>

> Presented at the Thirty-seventh Annual Meeting of The Society of

> Thoracic Surgeons, New Orleans, LA, Jan 29-31, 2001.

>

> J. Devaney MDa, Mark D. Iannettoni MDa, Mark B. Orringer

> MDCorresponding Author Contact Information, E-mail The

Corresponding

> Author, a and Becky Marshalla

>

> a Section of Thoracic Surgery, Department of Surgery, University of

> Michigan Medical Center, Ann Arbor, Michigan, USA

>

> Abstract

>

> Background. In 1989, we predicted an increasing number of

> esophagectomies for megaesophagus and for recurrent symptoms after

> prior esophagomyotomy or balloon dilatation for achalasia. Patient

> selection in this group is challenging, as the potential operative

> morbidity of an esophagectomy must be weighed against the expected

> clinical outcome after a redo esophagomyotomy or alternative

> procedures designed to salvage the native esophagus.

>

> Methods. The hospital records of 93 patients undergoing

esophagectomy

> for achalasia during the past 20 years were reviewed

retrospectively

> and the results of operation assessed using our prospectively

> established Esophageal Resection Database and follow-up information

> obtained through personal contact with the patients.

>

> Results. Patient age averaged 51 years. Indications for

esophagectomy

> included tortuous megaesophagus (64%), failure of prior myotomy

(63%),

> and associated reflux stricture (7%). Ninety-four percent of the

> patients underwent a transhiatal esophagectomy. Stomach was used as

> the esophageal substitute in 91% cases. Intraoperative blood loss

> averaged 672 mL. Postoperative length of stay averaged 12.5 days.

> Major complications included anastomotic leak (10%), recurrent

> laryngeal nerve injury (5%), delayed mediastinal bleeding requiring

> thoracotomy (2%), and chylothorax (2%). There were 2 hospital

deaths

> (2%) from respiratory insufficiency and sepsis. Follow-up has

averaged

> 38 months. In all, 95% of patients eat well; nearly 50% have

required

> an anastomotic dilatation; troublesome regurgitation has been rare;

> and 4% have refractory postvagotomy dumping.

>

> Conclusions. Esophagectomy, preferably through a transhiatal

approach,

> is generally safe and effective therapy in selected patients with

> achalasia. Unique technical considerations include difficulty

> encircling the dilated cervical esophagus, deviation of the

esophagus

> into the right chest, large aortic esophageal arteries, and

adherence

> of the exposed esophageal submucosa to the adjacent aorta after

prior

> myotomy.

>

> Abstract #2

> Transhiatal esophagectomy for treatment of benign and malignant

> esophageal disease

>

> Orringer, M B; Marshall, B; Iannettoni, M D

>

> Section of General Thoracic Surgery, Department of Surgery,

University

> of Michigan Medical Center, 2120 Taubman Health Care Center, 1500

E.

> Medical Center Drive, Box 0344, Ann Arbor, Michigan 48109, USA; e-

mail

> morrinumich (DOT) <mailto:morrin%40umich.edu> edu

>

> Abstract

>

> Since our initial 1978 report, we have performed transhiatal

> esophagectomy (THE) in 1085 patients with intrathoracic esophageal

> disease: 285 (26%) benign lesions and 800 (74%) malignant lesions

> (4.5% upper, 22% middle, and 73.5% lower third/cardia). THE was

> possible in 97% of patients in whom it was attempted;

reconstruction

> was performed at the same operation in all but six patients. The

> esophageal substitute was positioned in the original esophageal

bed in

> 98%, stomach being used in 782 patients (96%) and colon in those

with

> a prior gastric resection. Hospital mortality was 4%, with three

> deaths due to uncontrollable intraoperative hemorrhage. Major

> complications included anastomotic leak (13%),

atelectasis/pneumonia

> prolonging hospitalization (2%), recurrent laryngeal nerve

paralysis,

> chylothorax, and tracheal laceration (< 1% each). There were five

> reoperations for mediastinal bleeding within 24 hours of THE.

> Intraoperative blood loss averaged 689 ml. Altogether, 78% of the

> patients had no postoperative complications. Actuarial survival of

the

> cancer patients mirrors that reported after transthoracic

> esophagectomy. Late functional results are good or excellent in

80%.

> Approximately 50% have required one or more anastomotic

dilatations.

> With intensive preadmission pulmonary and physical conditioning,

use

> of a side-to-side staple technique (which has reduced the cervical

> esophagogastric anastomotic leak rate to less than 3%), and

> postoperative epidural anesthesia, the need for an intensive care

unit

> stay has been eliminated and the length of hospital stay was

reduced

> to 7 days. We concluded that THE can be achieved in most patients

> requiring esophageal resection for benign and malignant disease and

> with greater safety and less morbidity than the traditional

> transthoracic approaches.

>

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