Guest guest Posted January 3, 2007 Report Share Posted January 3, 2007 , The possibility of recovery has a great deal to do with the willingness of your uncle to do what it may be suggested he do. It may also depend on someone else---yourself or another person, doing what needs to be done. My suggestion is that you get in touch with the person who runs this site: http://survivecancerfoundation.org I would telephone him to see what he says. It is very likely he will recommend raw juices, in which case, someone will have to prepare them for your uncle. There will of course be other things that will be recommended. The person who runs that site recently helped very significantly a young man with " incurable " bladder cancer. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2007 Report Share Posted January 4, 2007 ONe more approval:2nd today 3-Jan-07 10:34 am Oncolytics Biotech Inc. Announces Approval for U.K. Clinical Trial Investigating REOLYSIN® in Combination with Gemcitabine Wednesday January 3, 10:30 am ET CALGARY, Jan. 3 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ( " Oncolytics " ) (TSX:ONC, NASDAQ:ONCY) announced today that it has received a letter of approval from the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) for its Clinical Trial Application (CTA) to begin a clinical trial using intravenous administration of REOLYSIN® in combination with gemcitabine (Gemzar®) in patients with advanced cancers including pancreatic, lung and ovarian. The principal investigators are Dr. Johann de Bono of The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London and Professor Jeff of the University of Glasgow and the Beatson Oncology Centre in Glasgow, Scotland. Gemcitabine is used in patients with lung, pancreatic and ovarian cancers and is also used widely in the treatment of many other types of cancers. " The combination of REOLYSIN® and gemcitabine was synergistic in preclinical studies, " said Dr. Brad , President and CEO of Oncolytics. " The data gathered in this study is expected to assist the company in further defining the optimal path to product registration. Drug combination studies allow us to investigate REOLYSIN® with drugs that are part of the current standard of care. " Preclinical studies conducted at Cornell University demonstrated that the combination of gemcitabine and REOLYSIN® was synergistic against selected cancer cell lines. This work was verified by additional studies conducted by the U.S. National Cancer Institute (NCI). This trial (REO 009) has two components. The first is an open-label, dose-escalating, non-randomized study of REOLYSIN® given intravenously with gemcitabine every three weeks. A standard dosage of gemcitabine will be delivered with escalating dosages of REOLYSIN® intravenously. A maximum of three cohorts will be enrolled in the REOLYSIN® dose escalation portion. The second component of the trial will immediately follow and will include the enrolment of a further 12 patients at the maximum dosage of REOLYSIN® in combination with a standard dosage of gemcitabine. Eligible patients include those who have been diagnosed with advanced or metastatic solid tumours including pancreatic, lung and ovarian cancers that are refractory (have not responded) to standard therapy or for which no curative standard therapy exists. The primary objective of the trial is to determine the Maximum Tolerated Dose (MTD), Dose-Limiting Toxicity (DLT), recommended dose and dosing schedule and safety profile of REOLYSIN® when administered in combination with gemcitabine. Secondary objectives include the evaluation of immune response to the drug combination, the body's response to the drug combination compared to chemotherapy alone and any evidence of anti-tumour activity. In the U.K. and the U.S., approximately 280,000 people are diagnosed with pancreatic, lung and ovarian cancers every year. Quote Link to comment Share on other sites More sharing options...
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