forskolin, was Epilepsy and mercury - thoughts and request for discussion

[Guest guest]

I don't think I replied on this thread a month ago, for which I apologize.

My son Elliot ended up at Children's Hospital of San Diego in Jan.1999 after

we tried forskolin for nine days. If he had a seizure disorder before then,

we didn't know about it. There was no mistaking it after the forskolin,

although the neurologist thought the seizure might have been an " occular

tic. " Elliot had pronounced and escalating tics after 8 days on the

forskolin, which continued to accelerate after the forskolin was

discontinued.

It tooks weeks or months to reduce the tics to low levels. Epsom salt baths

and B vitamins helped. After cod liver oil supplementation and lots of fish

eating, the seizures resumed or increased to noticeable levels in September

99. Depakote, thyroid medication, and manipulation of the fats in his diet,

stopped the seizures (among other things.)

I wouldn't touch forskolin with a 10 foot pole.

FWIW

Lorilyn

[ ] Epilepsy and mercury - thoughts and

> request for

> > discussion

> >

> >

> > >I saw some discussion in the Textbook of Natural Medicine about

> epilepsy

> > >being due to low cyclic AMP and/or increased cyclic GMP.

> > >

> > >They mentioned a chinese herbal rememdy for epilepsy which

> increases cAMP.

> > >

> > >The over the counter nutritional supplement forskolin, or Coleus

> > Forskohlii

> > >extract (sometimes also referred to as forskohlii) increases cAMP.

> > Caffeine

> > >and theophylline also increase cAMP (by inhibiting its breakdown).

> > >

> > >Mercury and other heavy metal toxins decrease the activity of the

> enzyme

> > that

> > >makes cyclic AMP in brain tissue at physiologically relevant

> > concentrations.

> > >

> > >Does this ring a bell with anyone? Thoughts? What have people's

> > experiences

> > >been?

> > >

> > >Andy Cutler

> > >

> > >

> > >

> > >

[Guest guest]

Lorilyn

You probably have a kid like mine, very sensitive. The thing about

secretin, it is contraindicated in kids with seizures, I think becuase it

changes the biochemical makeup TOO FAST in their brains, and it pushes or

accelerates fatty acid problems. My child turned the pink of a bunny

rabbits eyes all over his body the first time we injected secretin, so,

nope, this ain't for him. BUT, for some kids, the cAMP can do wonders.

Most likely, those with seizures, PROBABLY have the myelin problems (imo)

and that their myeline sheeth is sensitive to OVERDRIVE. IT would be better

to DAMPEN their immune systems in their cases instead of ACTIVATE it. Fatty

acids are something to look at, but even then, NO CLO, becuase kids with

seizures are also sensitive to Megsons therapy! (talked to McGinnis about

that one).

Kathy

[ ] forskolin, was Epilepsy and mercury - thoughts and

request for discussion

>

>I don't think I replied on this thread a month ago, for which I apologize.

>

>My son Elliot ended up at Children's Hospital of San Diego in Jan.1999

after

>we tried forskolin for nine days. If he had a seizure disorder before

then,

>we didn't know about it. There was no mistaking it after the forskolin,

>although the neurologist thought the seizure might have been an " occular

>tic. " Elliot had pronounced and escalating tics after 8 days on the

>forskolin, which continued to accelerate after the forskolin was

>discontinued.

>

>It tooks weeks or months to reduce the tics to low levels. Epsom salt baths

>and B vitamins helped. After cod liver oil supplementation and lots of

fish

>eating, the seizures resumed or increased to noticeable levels in September

>99. Depakote, thyroid medication, and manipulation of the fats in his

diet,

>stopped the seizures (among other things.)

>

>I wouldn't touch forskolin with a 10 foot pole.

>FWIW

>Lorilyn

>

> [ ] Epilepsy and mercury - thoughts and

>> request for

>> > discussion

>> >

>> >

>> > >I saw some discussion in the Textbook of Natural Medicine about

>> epilepsy

>> > >being due to low cyclic AMP and/or increased cyclic GMP.

>> > >

>> > >They mentioned a chinese herbal rememdy for epilepsy which

>> increases cAMP.

>> > >

>> > >The over the counter nutritional supplement forskolin, or Coleus

>> > Forskohlii

>> > >extract (sometimes also referred to as forskohlii) increases cAMP.

>> > Caffeine

>> > >and theophylline also increase cAMP (by inhibiting its breakdown).

>> > >

>> > >Mercury and other heavy metal toxins decrease the activity of the

>> enzyme

>> > that

>> > >makes cyclic AMP in brain tissue at physiologically relevant

>> > concentrations.

>> > >

>> > >Does this ring a bell with anyone? Thoughts? What have people's

>> > experiences

>> > >been?

>> > >

>> > >Andy Cutler

>> > >

>> > >

>> > >

>> > >

[Guest guest]

Kathy,

You've really got my head whirling with this message!! My daughter's

face turned red shortly after her secretin infusion, (we discontinued that

treatment method promptly)she canNOT tolerate CLO, and her comprehensive

stool analysis indicated that she is in a state of hyperimmunity (at least

in her GI system) . Although her sleep-deprived-sleep EEG (not an overnight

sleep EEG) indicated no seizure activity, I have anguished over the

possibility that she may be having minute ones that we cannot detect which

might explain why over the years she has gained some language only to loose

it completely shortly thereafter. sob. why her coloring will be healthy

for a time and then, for inexplicable reasons, turn palid.

ideas?

[ ] Epilepsy and mercury - thoughts and

> >> request for

> >> > discussion

> >> >

> >> >

> >> > >I saw some discussion in the Textbook of Natural Medicine about

> >> epilepsy

> >> > >being due to low cyclic AMP and/or increased cyclic GMP.

> >> > >

> >> > >They mentioned a chinese herbal rememdy for epilepsy which

> >> increases cAMP.

> >> > >

> >> > >The over the counter nutritional supplement forskolin, or Coleus

> >> > Forskohlii

> >> > >extract (sometimes also referred to as forskohlii) increases cAMP.

> >> > Caffeine

> >> > >and theophylline also increase cAMP (by inhibiting its breakdown).

> >> > >

> >> > >Mercury and other heavy metal toxins decrease the activity of the

> >> enzyme

> >> > that

> >> > >makes cyclic AMP in brain tissue at physiologically relevant

> >> > concentrations.

> >> > >

> >> > >Does this ring a bell with anyone? Thoughts? What have people's

> >> > experiences

> >> > >been?

> >> > >

> >> > >Andy Cutler

> >> > >

> >> > >

> >> > >

> >> > >

[Guest guest]

We have never tried secretin (keep planning to, but haven't) so I can't

comment on whether it would work for Elliot.

He does seem to have an overactive immune response...high measles and

chickenpox titers, seldom ill, etc. This is consistent with Blood Type

Theory, as Elliot is Type O.

I don't think cod liver oil was always a problem for Elliot. We used it, on

a DAN doctor's advise, for quite a while in 97-98. It may be part of why he

uses his eyes normally, not out of the sides as he once did. It may have

been part of why Monolaurin worked well for him, as one needs vitamin A to

fight off measles. It is even possible that his then-undiagnosed thyroid

problems made vitamin A metabolism problematic.

But we used cod liver oil, on and off, for years. (Dale brand,

don't know if it has mercury or not.) We ate fish several times a week,

particularly fatty fish like tuna, salmon, cod. His mercury was probably

increasing, his thyroid was probably getting worse, and his fatty acids were

seriously out of balance. He was two standard deviations high on DHA and

EPA on his Kennedy Krieger panel late last year, after the seizures began in

earnest.

If I had it to do over, I would run the KK panel before supplementing oils.

If a doctor wouldn't sign for that, I would use borage or evening primrose

before and/or with the cod liver oil, and I would supplement the cod liver

oil only 6 months.

Lorilyn

P.S. Anyone have Maureen McD's email address? I am on-line so much because

I am looking for a response from her, to an email that I may have sent to

the wrong address.

[Guest guest]

Here are a couple of thoughts....

She sounds like my ...but, here are some things to work on, (IMO)

1. Has she done a urine organic acid screen? This would detect is she has

abnormalities in energy metabolisms? (particularly carbo metabolism and fat

metabolism)

2. Does she have an over or under active thyroid? (common) Adrenal

insufficiency? (common)

3. How much oxygen saturation is she getting at night (a lot of our kids

have large large tonsils)?

4. Have you checked her for LKS (landau Kleffner syndrome, mini siezures at

night while sleeping, which regresses language during the day)

5. The greying that you see could be a consequence of a mitochondrial

disorder? No worry, this is quite commonin our kiddos, as in #1, check to

see if she has waste products in her urine, ie LACTATE and PYRUVATE which by

the way are also caused by mercury poisining.

6. Put her on HIGH antioxidants, of late I am finding MICROHYDIN has

changed this paloour in my kids. Look up Microhydin on a search, i know,

another ca ching, but I find the science fascinating. Also put her on

CoQ10, B1 thiamin, Biotin, B-6, and all the complex B's for that matter,

B-12 injections (intermediate), Spectrazyme by metagenics and Yeast avenger

by CFSN.com as well as Magnesium Sulphar Baths (epsom baths), Pregnelelone,

CDP Choline, Inisotol, AMBROTOSE (dampens the immune system as a true immune

biological response modifier).www.glycoscience.com along withVitamin C, E

and K, Melatonin, Possibly Grape Seed Extract, and even think of homeopathic

drainers such as mercurius (www.hvslabs.com ).

7. These things are discussed on intervenonelist (my list) as well as

willissonelist . I will also forward you a paper by Williss Langford.

8. NEVER give CLO to kids with seizures UNTIL you have worked on how their

bodies convert it. At first try EPO (evening primrose) and or MONOLAURIN or

lauric acid or cocunut oil for a while first. Dr McGinniss has seen a

corrolation with kids with seizures and the use of CLO. Something to do

with their Delta 6 conversions, they need to work on omega 3's first.

Getting a fatty acid test through Body bio would prove to be interesting for

you.

9. A stool analysis from Great Smokies, to see if their is undigested fats

or and some lovely parasitic creatures.

Blessings, and of course, these are IMO thoughts...

Kathy

Re: [ ] forskolin, was Epilepsy and mercury - thoughts

and request for discussion

>

>Kathy,

> You've really got my head whirling with this message!! My daughter's

>face turned red shortly after her secretin infusion, (we discontinued that

>treatment method promptly)she canNOT tolerate CLO, and her comprehensive

>stool analysis indicated that she is in a state of hyperimmunity (at least

>in her GI system) . Although her sleep-deprived-sleep EEG (not an

overnight

>sleep EEG) indicated no seizure activity, I have anguished over the

>possibility that she may be having minute ones that we cannot detect which

>might explain why over the years she has gained some language only to loose

>it completely shortly thereafter. sob. why her coloring will be healthy

>for a time and then, for inexplicable reasons, turn palid.

> ideas?

>

>

> [ ] Epilepsy and mercury - thoughts and

>> >> request for

>> >> > discussion

>> >> >

>> >> >

>> >> > >I saw some discussion in the Textbook of Natural Medicine about

>> >> epilepsy

>> >> > >being due to low cyclic AMP and/or increased cyclic GMP.

>> >> > >

>> >> > >They mentioned a chinese herbal rememdy for epilepsy which

>> >> increases cAMP.

>> >> > >

>> >> > >The over the counter nutritional supplement forskolin, or Coleus

>> >> > Forskohlii

>> >> > >extract (sometimes also referred to as forskohlii) increases cAMP.

>> >> > Caffeine

>> >> > >and theophylline also increase cAMP (by inhibiting its breakdown).

>> >> > >

>> >> > >Mercury and other heavy metal toxins decrease the activity of the

>> >> enzyme

>> >> > that

>> >> > >makes cyclic AMP in brain tissue at physiologically relevant

>> >> > concentrations.

>> >> > >

>> >> > >Does this ring a bell with anyone? Thoughts? What have people's

>> >> > experiences

>> >> > >been?

>> >> > >

>> >> > >Andy Cutler

>> >> > >

>> >> > >

>> >> > >

>> >> > >

[Guest guest]

Monolaurin also acts as an antiviral against enveloping viruses such as

measles and chicken pox! Go on any search and find the HIV people using for

T cell response to HIV! They sware by it, so I began using it too. Good

things have transpired becuase of it. Wondering if it just slips off the

virus, or pokes a whole in the envelope for NK cells to recognize it. If

their is enterocolitis like things going on with your kids list, this may be

highly underlooked as a great protocol (in our already large protocol heh?).

It is often low on on the KK test if you look under lauric acid. It also

helps you metabolize things better?

Kathy

Re: [ ] forskolin, was Epilepsy and mercury - thoughts

and request for discussion

>

>

>We have never tried secretin (keep planning to, but haven't) so I can't

>comment on whether it would work for Elliot.

>

>He does seem to have an overactive immune response...high measles and

>chickenpox titers, seldom ill, etc. This is consistent with Blood Type

>Theory, as Elliot is Type O.

>

>I don't think cod liver oil was always a problem for Elliot. We used it,

on

>a DAN doctor's advise, for quite a while in 97-98. It may be part of why

he

>uses his eyes normally, not out of the sides as he once did. It may have

>been part of why Monolaurin worked well for him, as one needs vitamin A to

>fight off measles. It is even possible that his then-undiagnosed thyroid

>problems made vitamin A metabolism problematic.

>

>But we used cod liver oil, on and off, for years. (Dale brand,

>don't know if it has mercury or not.) We ate fish several times a week,

>particularly fatty fish like tuna, salmon, cod. His mercury was probably

>increasing, his thyroid was probably getting worse, and his fatty acids

were

>seriously out of balance. He was two standard deviations high on DHA and

>EPA on his Kennedy Krieger panel late last year, after the seizures began

in

>earnest.

>

>If I had it to do over, I would run the KK panel before supplementing oils.

>If a doctor wouldn't sign for that, I would use borage or evening primrose

>before and/or with the cod liver oil, and I would supplement the cod liver

>oil only 6 months.

>

>Lorilyn

>P.S. Anyone have Maureen McD's email address? I am on-line so much because

>I am looking for a response from her, to an email that I may have sent to

>the wrong address.

>

>

>