Parasites and cod liver oil

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Dear listmates,

this is from a personal communication and might be of interest.

Regards,

Katharina

--------------quote:

1: Am J Clin Nutr. 1989 Aug;50(2):346-52.

Qinghaosu, dietary vitamin E, selenium, and cod-liver oil: effect on the

susceptibility of mice to the malarial parasite Plasmodium yoelii.

Levander OA, Ager AL Jr, VC, May RG.

Human Nutrition Research Center, US Department of Agriculture, MD 20705.

Young female mice were fed torula-yeast-based diets deficient in vitamin E

or

selenium or supplemented with cod-liver oil to determine the effect of host

antioxidant status on the therapeutic efficacy of the Chinese traditional

antimalarial drug qinghaosu (QHS), a sesquiterpene endoperoxide. Vitamin E

deficiency enhanced the antimalarial action of QHS against Plasmodium

yoelii,

both in terms of decreased parasitemia and improved survival but Se

deficiency

did not. A vitamin E-deficient diet containing 5% cod-liver oil had such

strong

antimalarial activity in itself that no additional therapeutic benefit of

QHS

could be demonstrated. Hematocrit values in parasitized mice treated with

QHS or

fed the cod-liver-oil-supplemented, vitamin E-deficient diet were normal.

Nutritional manipulation of host antioxidant status may provide a promising

prophylactic and/or therapeutic tool for the control of malaria.

PMID: 2756922 [PubMed - indexed for MEDLINE]

----------------------end of quote.

Mit freundlichen Gruessen

Katharina Gutsche

Sincere regards,

Katharina

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Dipl.-Psych. Katharina Gutsche, M.A. Psycholinguistik

Heilpraktikerin (Psychotherapie)

Klinische Psychologie

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