Guest guest Posted March 27, 2004 Report Share Posted March 27, 2004 Hi, here is an article showing that garlica reduced cancer cell prolifeation in dose dependant manner with certain tumor types. moonbeam Phytomedicine 1999 Mar;6(1):7-11 The effects of garlic preparations against human tumor cell proliferation. Siegers CP, Steffen B, Robke A, Pentz R. Department of Toxicology, Medical University of Luebeck, Germany. siegers@... Epidemiological studies in China provide reason to suspect that a rich garlic content in the diet might reduce the proliferation of tumors in humans. When the garlic extract was supplemented with garlic powder (to 10% final concentration) there was a concentration-dependent clear inhibition of tumor cell growth (IC50 values of 330 micrograms/ml for HepG2 and 480 micrograms/ml for Caco-2 cells). The growth of the human lymphatic leukemia cell line CCRF CEM was significantly inhibited in a dose-dependent manner by both garlic powder and garlic extract at concentrations as low as 30 micrograms/ml. However, no potentiation of this effect occurred upon mixing of the two preparations. Our results suggest that the antiproliferative effects of garlic may be due to breakdown products of alliin, such as allicin or polysulfides, rather than alliin itself, since the addition of an alliinase system (garlic powder) to an alliin enriched preparation without alliinase (garlic extract) potentiated the effects observed with the two preparations alone. PMID: 10228605 [PubMed - indexed for MEDLINE] Quote Link to comment Share on other sites More sharing options...
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