Fw: [CircumcisedMen:1107] A 90% Successful AIDS Vaccine tested on only 30 volunteers

[Guest guest]

A cure is in the works. I hope you all will " be here for the cure " . Do NOT give

up hope for this. In our life time AIDS will be cured. Let there be no doubt. In

the mean time keep up with your treatments so you can be here for the cure.

[CircumcisedMen:1107] A 90% Successful AIDS Vaccine tested on only 30

volunteers

This 90 Percent Successful Vaccine May Be Our Best Chance to Eradicate AIDS

Spanish researchers have completed the first human trial of a new vaccine

against HIV. It has been successful in 90% of the HIV-free volunteers during

phase I testing. This vaccine brings great hope to eradicate this plague

forever.

The team lead by Dr no Esteban, a researcher at the Spanish National

Research Council's Biotechnology National Centre, has been working on this

method since 1999. They are using an attenuated virus called the MVA-B, a

variation of the Modified Ankara Vaccinia, which was previously used to

eradicate smallpox. The Modified Ankara Vaccinia also forms the base of other

vaccines. The B refers to the HIV-B, the most common HIV subtype in Europe.

Dr Esteban's team inserted the HIV genesGag, Pol, Nef and Env in MVA's genetic

sequence. In 2008, they tried the resulting HIV nuke on mice and monkeys. It was

a complete success.

Successful human test

The first human test results were published in Vaccine and Journal of Virology.

In the experiment, scientists injected the vaccine in 24 of 30 HIV-free

volunteers. Six volunteers were treated with a placebo vaccine—they didn't

experience any effect. But 90% of the treated subjects developed a very strong

immunological response against the HIV virus. 85% kept the immunological

reaction for at least one year, which is really good news.

According to their results, there were no significant secondary effects in any

of the patients, which was one of the major objectives of to be tested in this

clinical trial.

Despite the success, Dr Esteban is cautious:

[T]he treatment has only been tested on 30 volunteers and, while [the vaccine]

provokes a powerful response in most of the cases, it's still to soon if the

resulting defense would be effective against an actual [HIV] infection.

The team will now start another phase I trial, injecting the vaccine in

HIV-infected people. The objective of this trial is to test the therapeutical

effect of the vaccine in these patients.

According to Dr Esteban, " in principle, the immunological profile of MVA-B

satisfies the requirements for a promising vaccine against the HIV, like the

creation of antibodies and the activation of key cells in the defense against

the virus. " Sadly, it is still far away from commercialization: they need to

test this on phase II and III trials, injecting vaccinated volunteers with the

actual HIV virus on a larger scale.

Hopefully, one day this one will nail that HIV bastard down. [CSIC—In Spanish]

Source:

http://gizmodo.com/5844706/this-90-successful-vaccine-may-be-our-best-chance-to-\

eradicate-aids

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