Guest guest Posted October 28, 2003 Report Share Posted October 28, 2003 " The Life Extension Foundation is constantly uncovering information to provide the cancer patient with more ammunition to battle their disease. A special website has been established for the purpose of updating patients on new findings that directly pertain to the cancer protocols. Whenever Life Extension discovers information that points to a better way of treating cancer, it will be posted on the website www.lefcancer.org " . [From their recent newsletter] Protocol Breast Cancer Breast cancer occurs when cells in the breast tissue divide and grow without control. In a healthy body, the cell cycle is the natural mechanism that regulates the creation, growth, and death of cells. It is this mechanism that regulates cell division, allowing the creation of new tissue as older cells die. When the normal cell regulators malfunction and cells do not die at the proper rate, there is a failure of apoptosis (programmed cell death) and cell growth goes unchecked. As a result, cancer begins to develop as cells divide without control, accumulating into a mass of extra tissue called a malignant tumor. As a tumor grows, it elicits new capillary growth (angiogenesis) from the surrounding normal tissues and diverts blood supply and nutrients away from the tissue to feed itself. Unregulated angiogenesis can facilitate the growth of cancer throughout the body. An important aspect in any reproductive cancer is whether the tumor growth is hormonally driven. Often breast cancer tumors require hormones for growth. This is known as a receptor-positive tumor. This type of cancer poses a unique problem because the hormones involved in tumor growth are either estrogen or progesterone or both. Estrogen and progesterone are naturally occurring hormones that the body produces in varying amounts throughout one's lifetime. To complicate the situation further, these hormones are essential for many other physiological functions, such as bone integrity. In 1991, researchers at the Institute for Hormone Research announced that they had been able to induce the body to convert the stronger form of estrogen (estradiol) into the weaker form (estriol) without using drugs. Estriol is considered to be a more desirable form of estrogen. It is less active than estradiol, so when it occupies the estrogen receptor, it blocks estradiol's strong " grow " signals. It took only 1 week to prove that the conversion of estradiol to estriol could be accomplished without drugs. Using a natural substance, researchers were able to increase the conversion of estradiol to estriol by 50% in 12 healthy people (Michnovicz et al. 1991). Next, they tested the natural substance in female mice prone to developing breast cancer. The incidence of cancer and the number of tumors fell significantly. The substance was indole-3-carbinol (IC3), a phytochemical isolated from cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, turnips, kale, green cabbage, mustard seed, etc.). I3C was then given to 17 men and women for 2 months. Again, levels of strong estrogen declined, and levels of weak estrogen increased. But more importantly, the level of an estrogen metabolite associated with breast and endometrial cancer (16,alpha-hydroxyestrone) fell (Bradlow et al. 1991). This cancer protocol raises many issues that are subject to change as new data emerge. Furthermore, cancer is still a disease with unacceptably high mortality rates, and none of our suggested treatment regimens can guarantee a cure. Featured Products of the Week Indole-3-carbinol A summary of recent studies shows that this vegetable extract: Increases the conversion of estradiol to ?weaker? (2OHE) estrogen, which has been shown to reduce breast cancer incidence Works in estrogen receptor negative breast cancer cells. Stops human cancer cells from growing (54-61%) and provokes the cells to self-destruct (apoptosis). Inhibits MCF7 human breast cancer cells better than tamoxifen under laboratory conditions. Protects against the environmental toxin, dioxin. Restores p21 tumor suppressor gene. Provides antioxidant protection. Super Green Tea Extract The initial interest in studying green tea came from epidemiological studies showing a lower rate of cancer in regions where green tea was consumed. Life Extension Buyers Club?s 95% green tea extracts, in either lightly caffeinated or decaffeinated form, are standardized to provide 35% of epigallocatechin gallate (EGCG). Published research shows that EGCG is the most potent cancer cell suppressing polyphenol found in green tea. Some noteworthy studies on green tea include: When non-Hodgkins lymphoma cells were transplanted into mice, green tea prevented 50% of the tumors from taking hold and significantly inhibited growth of the tumors (Leukemia 2000 Aug;14(8):1477-82). Green tea was shown to help protect against the progression of atrophic gastritis in Japanese men (Scand J Gastroenterol 2000 May;35(5)476-81). Phenol sulsotransferases are involved in cancer growth, and green tea extract was shown to inhibit this activity in a human colon cancer call line (Biol Pharm Bull 2000 Jun;23(6):695-9). Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2003 Report Share Posted October 28, 2003 " The Life Extension Foundation is constantly uncovering information to provide the cancer patient with more ammunition to battle their disease. A special website has been established for the purpose of updating patients on new findings that directly pertain to the cancer protocols. Whenever Life Extension discovers information that points to a better way of treating cancer, it will be posted on the website www.lefcancer.org " . [From their recent newsletter] Protocol Breast Cancer Breast cancer occurs when cells in the breast tissue divide and grow without control. In a healthy body, the cell cycle is the natural mechanism that regulates the creation, growth, and death of cells. It is this mechanism that regulates cell division, allowing the creation of new tissue as older cells die. When the normal cell regulators malfunction and cells do not die at the proper rate, there is a failure of apoptosis (programmed cell death) and cell growth goes unchecked. As a result, cancer begins to develop as cells divide without control, accumulating into a mass of extra tissue called a malignant tumor. As a tumor grows, it elicits new capillary growth (angiogenesis) from the surrounding normal tissues and diverts blood supply and nutrients away from the tissue to feed itself. Unregulated angiogenesis can facilitate the growth of cancer throughout the body. An important aspect in any reproductive cancer is whether the tumor growth is hormonally driven. Often breast cancer tumors require hormones for growth. This is known as a receptor-positive tumor. This type of cancer poses a unique problem because the hormones involved in tumor growth are either estrogen or progesterone or both. Estrogen and progesterone are naturally occurring hormones that the body produces in varying amounts throughout one's lifetime. To complicate the situation further, these hormones are essential for many other physiological functions, such as bone integrity. In 1991, researchers at the Institute for Hormone Research announced that they had been able to induce the body to convert the stronger form of estrogen (estradiol) into the weaker form (estriol) without using drugs. Estriol is considered to be a more desirable form of estrogen. It is less active than estradiol, so when it occupies the estrogen receptor, it blocks estradiol's strong " grow " signals. It took only 1 week to prove that the conversion of estradiol to estriol could be accomplished without drugs. Using a natural substance, researchers were able to increase the conversion of estradiol to estriol by 50% in 12 healthy people (Michnovicz et al. 1991). Next, they tested the natural substance in female mice prone to developing breast cancer. The incidence of cancer and the number of tumors fell significantly. The substance was indole-3-carbinol (IC3), a phytochemical isolated from cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, turnips, kale, green cabbage, mustard seed, etc.). I3C was then given to 17 men and women for 2 months. Again, levels of strong estrogen declined, and levels of weak estrogen increased. But more importantly, the level of an estrogen metabolite associated with breast and endometrial cancer (16,alpha-hydroxyestrone) fell (Bradlow et al. 1991). This cancer protocol raises many issues that are subject to change as new data emerge. Furthermore, cancer is still a disease with unacceptably high mortality rates, and none of our suggested treatment regimens can guarantee a cure. Featured Products of the Week Indole-3-carbinol A summary of recent studies shows that this vegetable extract: Increases the conversion of estradiol to ?weaker? (2OHE) estrogen, which has been shown to reduce breast cancer incidence Works in estrogen receptor negative breast cancer cells. Stops human cancer cells from growing (54-61%) and provokes the cells to self-destruct (apoptosis). Inhibits MCF7 human breast cancer cells better than tamoxifen under laboratory conditions. Protects against the environmental toxin, dioxin. Restores p21 tumor suppressor gene. Provides antioxidant protection. Super Green Tea Extract The initial interest in studying green tea came from epidemiological studies showing a lower rate of cancer in regions where green tea was consumed. Life Extension Buyers Club?s 95% green tea extracts, in either lightly caffeinated or decaffeinated form, are standardized to provide 35% of epigallocatechin gallate (EGCG). Published research shows that EGCG is the most potent cancer cell suppressing polyphenol found in green tea. Some noteworthy studies on green tea include: When non-Hodgkins lymphoma cells were transplanted into mice, green tea prevented 50% of the tumors from taking hold and significantly inhibited growth of the tumors (Leukemia 2000 Aug;14(8):1477-82). Green tea was shown to help protect against the progression of atrophic gastritis in Japanese men (Scand J Gastroenterol 2000 May;35(5)476-81). Phenol sulsotransferases are involved in cancer growth, and green tea extract was shown to inhibit this activity in a human colon cancer call line (Biol Pharm Bull 2000 Jun;23(6):695-9). Quote Link to comment Share on other sites More sharing options...
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