Guest guest Posted March 6, 2003 Report Share Posted March 6, 2003 This product has gotten a lot of play in the media awhile back but I have heard no mention of it from anyone's personal experience. Is there anyone out there who has used this product for any length of time? If so , would like to see something on that experience please. Many of these products come on the scene like Supernova's and soon slip into that eerie black hole never to be seen or heard from again. Before we put this one to bed would be nice to hear something about if from someone who has actually used it. Thanks, BOB > Herbal Treatment Shows Promise Against Prostate Cancer > > It suppressed cell growth in lab experiments > > By Serena Gordon > HealthScoutNews Reporter > > > > > > > FRIDAY, Dec. 20 (HealthScoutNews) -- An herbal formula sold under the brand > name Zyflamend may offer new treatment and prevention options for prostate > cancer patients, say Columbia University researchers. > The formula, a combination of 10 different herbs, suppressed the growth of > prostate cancer cells and caused many cells to self-destruct in lab > experiments, report the researchers. They presented their findings at a > recent meeting of the Society of Urologic Oncology at the National > Institutes of Health in Bethesda, Md. > > " This is a natural product that contains herbs and spices and in our lab > studies seems to have an effect on the cancer we looked at, " says one of the > study's authors, Dr. Katz, director of the Center for Holistic Urology > at Columbia-Presbyterian Medical Center in New York City. " The compound > needs future research on the clinical side, but it holds the potential for > prevention and reducing PSA (prostate-specific antigen) levels. " > > Prostate cancer is the most common cancer in men, except for skin cancer. > More than 189,000 men are diagnosed with this form of cancer every year, > according to the American Cancer Society. > > Zyflamend is made with a combination of turmeric, ginger, holy basil, hu > zhang, Chinese goldthread, barberry, oregano, rosemary, green tea and > Scutellaria baicalensis. > > The researchers added Zyflamend to prostate cancer cells in lab cultures. > They also tested the effects of curcumin, a compound from the spice > turmeric. Curcumin is believed to have an anti-inflammatory effect that > could reduce the growth of prostate cancer. > > They found Zyflamend reduced the growth of prostate cancer cells and induced > cell death, and that curcumin alone did not produce these effects. > > Dr. Korman, a urologist and prostate cancer specialist at > Beaumont Hospital in Royal Oak, Mich., says the results of this new study > are exciting. > > " Some of our most effective medicines come from plants, " says Korman, " and > these results are interesting and hopeful. " > > However, he cautions, " it's a big step to go from the lab to people. " > > Katz says the researchers are hopeful the therapy will be as effective in > people as it is in the lab, and they plan on conducting clinical trials in > the future. > > If it proves as effective as they hope, Katz says the herbal formula could > be used as preventative therapy because it has no significant side effects. > He says it could also, perhaps, be used as a treatment for men with small > tumors who don't want to undergo surgery or radiation if the trials go well. > > What To Do > > For more information on prostate cancer, visit the National Cancer > Institute. The American Cancer Society offers tips that may help to prevent > prostate cancer. > > > Herb Mix Nixes Prostate Cancer in Lab > > By DeNoon > WebMD Medical News Reviewed By Brunilda Nazario, MD > on Friday, December 13, 2002 > > > > Email to a friend > Printer-friendly version > > ______________________________________________________________________ _____ > > Dec. 13, 2002 -- A mixture of 10 herbs has several anti-cancer actions, > test-tube studies show. > > > In tests by Columbia University researchers Debra L. Bemis, PhD, E. > Katz, MD, and colleagues, the herb mixture slowed the growth of > prostate-cancer cells. It also doubled the rate at which the cancerous cells > committed suicide -- a natural anti-cancer activity known as apoptosis or > programmed cell death. The findings were presented at today's meeting of the > Society of Urologic Oncology. > > > Katz, director of Columbia-Presbyterian Medical Center's department of > holistic urology, notes that prostate cancer cells make a substance called > COX-2. A number of recent studies point to COX-2 as an important factor in > cancer-cell growth. In the Columbia studies, Zyflamend decreased COX-2 > activity about as well as a potent COX-2-inhibiting drug. > > > " This [COX-2] area of research is very exciting in prostate and other > cancers, " Katz tells WebMD. " With this herbal mixture, we are going to look > at opening a clinical trial to see its effect in patients at high risk of > prostate cancer. It is a unique thing as it is a natural compound. This is a > new area of research. The study findings don't necessarily translate to > cancer prevention in humans, but there is enough information here to make us > want to look at it in a clinical trial. " > > > The herbal mix is called Zyflamend, from New Chapter Inc., and has 10 herbs: > holy basil, turmeric, ginger, green tea, rosemary, hu zhang, Chinese > goldthread, barberry, oregano, and Scutellaria biacalensis. Extracts of some > of these herbs are known to have some anti-inflammatory effects. > > > Aspirin, ibuprofen, and naproxen also inhibit COX-2. So do the newer drugs > Celebrex and Vioxx, which are specifically targeted at COX-2. So why use > herbs to get the same effect? M. Newmark, president of New Chapter > Inc. thinks herbs may offer more. > > > " We wondered whether a total herbal approach using the nuances and > complexity of the whole herb might have advantages over a single-molecule > drug, " Newmark tells WebMD. " With an herb there could be thousands of > molecules interacting with one another. We like the way nature organizes > these molecules in full herbal form. " > > > Katz already recommends herbal preparations for patients at high risk of > prostate cancer. These are men with high PSA levels but without evidence of > cancer, and men with a family history of prostate cancer. > > > " There is lycopene, from tomatoes, " Katz says. " People with diets rich in > tomato extracts have a lower incidence of prostate cancer, and men who took > lycopene before prostate surgery had smaller tumors with better surgical > margins. We also are studying GCP, which is made from soybeans. And in the > large SELECT trials, sponsored by the National Cancer Institute, we are > looking at selenium and vitamin E. This trial has a five-year patient > accrual period and a seven-year follow-up. I think these things can be take > in low doses. They are nontoxic and inexpensive. Right now, rather than > waiting around for 12 years, if you have one of these high risk feature why > not take them? " > > > K. Brawer, MD, director of Seattle's Northwest Prostate Institute, > says Katz's work is well respected by other urologists. He notes that there > are several clinical trials looking at whether COX-2 inhibitors can prevent > prostate cancer. And he says that while proof is lacking, there is evidence > that people who take some supplements have a lower incidence of prostate > cancer. > > > " What I tell patients is that the data is not conclusive, but there are a > number of compounds -- like lycopene, selenium, and vitamin E - that seem to > be linked to decreased incidence of prostate cancer, " Brawer tells WebMD. " I > think to the extent you can extrapolate from studies that weren't > specifically about prostate cancer, these compounds are probably safe and > may have efficacy. But there are other compounds that can do harm. One, > PC-SPEC, was a disaster. That showed we need to study these things carefully > to make sure they are safe and effective. " > > > ---------------------------------------------------------------------- ---- -- > ---- > > SOURCES: Abstract of presentation to Society of Urologic Oncology, > " Zyflamend, An Herbal COX-2 Inhibitor with In Vitro Anti-Prostate-Cancer > Activity, " D.L. Bemis et al. • Debra L. Bemis, PhD, Columbia University • > E. Katz, MD, director of the Center for Holistic Urology, > Columbia-Presbyterian Medical Center • K. Brawer, MD, director, > Northwest Prostate Institute, Seattle • M. Newmark, president, New > Chapter Inc. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 6, 2003 Report Share Posted March 6, 2003 This product has gotten a lot of play in the media awhile back but I have heard no mention of it from anyone's personal experience. Is there anyone out there who has used this product for any length of time? If so , would like to see something on that experience please. Many of these products come on the scene like Supernova's and soon slip into that eerie black hole never to be seen or heard from again. Before we put this one to bed would be nice to hear something about if from someone who has actually used it. Thanks, BOB > Herbal Treatment Shows Promise Against Prostate Cancer > > It suppressed cell growth in lab experiments > > By Serena Gordon > HealthScoutNews Reporter > > > > > > > FRIDAY, Dec. 20 (HealthScoutNews) -- An herbal formula sold under the brand > name Zyflamend may offer new treatment and prevention options for prostate > cancer patients, say Columbia University researchers. > The formula, a combination of 10 different herbs, suppressed the growth of > prostate cancer cells and caused many cells to self-destruct in lab > experiments, report the researchers. They presented their findings at a > recent meeting of the Society of Urologic Oncology at the National > Institutes of Health in Bethesda, Md. > > " This is a natural product that contains herbs and spices and in our lab > studies seems to have an effect on the cancer we looked at, " says one of the > study's authors, Dr. Katz, director of the Center for Holistic Urology > at Columbia-Presbyterian Medical Center in New York City. " The compound > needs future research on the clinical side, but it holds the potential for > prevention and reducing PSA (prostate-specific antigen) levels. " > > Prostate cancer is the most common cancer in men, except for skin cancer. > More than 189,000 men are diagnosed with this form of cancer every year, > according to the American Cancer Society. > > Zyflamend is made with a combination of turmeric, ginger, holy basil, hu > zhang, Chinese goldthread, barberry, oregano, rosemary, green tea and > Scutellaria baicalensis. > > The researchers added Zyflamend to prostate cancer cells in lab cultures. > They also tested the effects of curcumin, a compound from the spice > turmeric. Curcumin is believed to have an anti-inflammatory effect that > could reduce the growth of prostate cancer. > > They found Zyflamend reduced the growth of prostate cancer cells and induced > cell death, and that curcumin alone did not produce these effects. > > Dr. Korman, a urologist and prostate cancer specialist at > Beaumont Hospital in Royal Oak, Mich., says the results of this new study > are exciting. > > " Some of our most effective medicines come from plants, " says Korman, " and > these results are interesting and hopeful. " > > However, he cautions, " it's a big step to go from the lab to people. " > > Katz says the researchers are hopeful the therapy will be as effective in > people as it is in the lab, and they plan on conducting clinical trials in > the future. > > If it proves as effective as they hope, Katz says the herbal formula could > be used as preventative therapy because it has no significant side effects. > He says it could also, perhaps, be used as a treatment for men with small > tumors who don't want to undergo surgery or radiation if the trials go well. > > What To Do > > For more information on prostate cancer, visit the National Cancer > Institute. The American Cancer Society offers tips that may help to prevent > prostate cancer. > > > Herb Mix Nixes Prostate Cancer in Lab > > By DeNoon > WebMD Medical News Reviewed By Brunilda Nazario, MD > on Friday, December 13, 2002 > > > > Email to a friend > Printer-friendly version > > ______________________________________________________________________ _____ > > Dec. 13, 2002 -- A mixture of 10 herbs has several anti-cancer actions, > test-tube studies show. > > > In tests by Columbia University researchers Debra L. Bemis, PhD, E. > Katz, MD, and colleagues, the herb mixture slowed the growth of > prostate-cancer cells. It also doubled the rate at which the cancerous cells > committed suicide -- a natural anti-cancer activity known as apoptosis or > programmed cell death. The findings were presented at today's meeting of the > Society of Urologic Oncology. > > > Katz, director of Columbia-Presbyterian Medical Center's department of > holistic urology, notes that prostate cancer cells make a substance called > COX-2. A number of recent studies point to COX-2 as an important factor in > cancer-cell growth. In the Columbia studies, Zyflamend decreased COX-2 > activity about as well as a potent COX-2-inhibiting drug. > > > " This [COX-2] area of research is very exciting in prostate and other > cancers, " Katz tells WebMD. " With this herbal mixture, we are going to look > at opening a clinical trial to see its effect in patients at high risk of > prostate cancer. It is a unique thing as it is a natural compound. This is a > new area of research. The study findings don't necessarily translate to > cancer prevention in humans, but there is enough information here to make us > want to look at it in a clinical trial. " > > > The herbal mix is called Zyflamend, from New Chapter Inc., and has 10 herbs: > holy basil, turmeric, ginger, green tea, rosemary, hu zhang, Chinese > goldthread, barberry, oregano, and Scutellaria biacalensis. Extracts of some > of these herbs are known to have some anti-inflammatory effects. > > > Aspirin, ibuprofen, and naproxen also inhibit COX-2. So do the newer drugs > Celebrex and Vioxx, which are specifically targeted at COX-2. So why use > herbs to get the same effect? M. Newmark, president of New Chapter > Inc. thinks herbs may offer more. > > > " We wondered whether a total herbal approach using the nuances and > complexity of the whole herb might have advantages over a single-molecule > drug, " Newmark tells WebMD. " With an herb there could be thousands of > molecules interacting with one another. We like the way nature organizes > these molecules in full herbal form. " > > > Katz already recommends herbal preparations for patients at high risk of > prostate cancer. These are men with high PSA levels but without evidence of > cancer, and men with a family history of prostate cancer. > > > " There is lycopene, from tomatoes, " Katz says. " People with diets rich in > tomato extracts have a lower incidence of prostate cancer, and men who took > lycopene before prostate surgery had smaller tumors with better surgical > margins. We also are studying GCP, which is made from soybeans. And in the > large SELECT trials, sponsored by the National Cancer Institute, we are > looking at selenium and vitamin E. This trial has a five-year patient > accrual period and a seven-year follow-up. I think these things can be take > in low doses. They are nontoxic and inexpensive. Right now, rather than > waiting around for 12 years, if you have one of these high risk feature why > not take them? " > > > K. Brawer, MD, director of Seattle's Northwest Prostate Institute, > says Katz's work is well respected by other urologists. He notes that there > are several clinical trials looking at whether COX-2 inhibitors can prevent > prostate cancer. And he says that while proof is lacking, there is evidence > that people who take some supplements have a lower incidence of prostate > cancer. > > > " What I tell patients is that the data is not conclusive, but there are a > number of compounds -- like lycopene, selenium, and vitamin E - that seem to > be linked to decreased incidence of prostate cancer, " Brawer tells WebMD. " I > think to the extent you can extrapolate from studies that weren't > specifically about prostate cancer, these compounds are probably safe and > may have efficacy. But there are other compounds that can do harm. One, > PC-SPEC, was a disaster. That showed we need to study these things carefully > to make sure they are safe and effective. " > > > ---------------------------------------------------------------------- ---- -- > ---- > > SOURCES: Abstract of presentation to Society of Urologic Oncology, > " Zyflamend, An Herbal COX-2 Inhibitor with In Vitro Anti-Prostate-Cancer > Activity, " D.L. Bemis et al. • Debra L. Bemis, PhD, Columbia University • > E. Katz, MD, director of the Center for Holistic Urology, > Columbia-Presbyterian Medical Center • K. Brawer, MD, director, > Northwest Prostate Institute, Seattle • M. Newmark, president, New > Chapter Inc. Quote Link to comment Share on other sites More sharing options...
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