SIDS article from BMJ - possible vaccine connection?

[Guest guest]

When they say that children who had received drug treatment in the week

before death were more likely to have died than controls, did they include

vaccines in that classification?

Meryl

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Editor's Choice | This Week in BMJ | Press releases

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Case-control study of sudden infant death syndrome in Scotland, 1992-5

Hazel , Angus Gibson, Tappin, Helen Brown

Abstract

Objective: To investigate the relation between routine infant care

practices and the sudden infant death syndrome in Scotland.

Methods: National study of 201 infants dying of the sudden infant death

syndrome (cases) and 276 controls by means of home interviews comparing

methods of infant care and socioeconomic factors.

Results: Sleeping prone (odds ratio 6.96 (95% confidence interval 1.51 to

31.97)) and drug treatment in the previous week (odds ratio 2.33 (1.10 to

4.94)) were more common in the cases than controls on multivariate

analysis. Smoking was confirmed as a significant risk factor (odds ratio

for mother and father both smoking 5.19 (2.26 to 11.91)). The risk

increased with the number of parents smoking (P<0.0001), with the number of

cigarettes smoked by mother or father (P=0.0001), and with bed sharing

(P<0.005). A new finding was an increased risk of dying of the syndrome for

infants who slept at night on a mattress previously used by another infant

or adult (odds ratio 2.51 (1.39 to 4.52)). However, this increased risk was

not established for mattresses totally covered by polyvinyl chloride.

Conclusions: Sleeping prone and parental smoking are confirmed as

modifiable risk factors for the sudden infant death syndrome. Sleeping on

an old mattress may be important but needs confirmation before

recommendations can be made.

ish Cot Death Trust,

Royal Hospital for Sick Children,

Glasgow G3 8SJ

Hazel , executive director

Angus Gibson, chairman

Tappin, senior lecturer in community paediatrics, University of Glasgow

Medical Statistics Unit,

University of Edinburgh Medical School,

Edinburgh EH8 9AG

Helen Brown, research associate

Correspondence to: Mrs .

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Sheri Nakken, R.N., MA

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