Re: Fw: Fw: Urgent - Info Needed

[Guest guest]

In a message dated 03/31/2000 15:20:32, arnoldgore@... writes:

<< Eat the whole fruit. Don't take silly shortcuts that may and probably

won't work. >>

Thanks for this post, Arnold, I was just wondering the same thing myself.

And, just to make sure, I put the entire raspberry(ies) into my flax

seed/cottage cheese, etc., etc., shake every day (organic ones, too). Sure

improves the flavor, and I hope does not interfere with other ingredients!

Joyce (H.)

[Guest guest]

Steve:

What makes you think that the extract of ellagiac acid which the

experimenter arrogantly presumes to be the ONLY effective component in Red

Raspberries in actuality will work isolsted from the so far undiscovered

cofactors in Red Raspberries! Eat the whole fruit. Don't take silly

shortcuts that may and probably won't work. The literature is filled with

studies of how isolated nutrients don't work but the whole foods do work.

Arnold Gore

Consumers Health Freedom Coalition

Re: Fw: Fw: Urgent - Info Needed

Eating grapes will give you a small amount of ellagic acid. Taking direct

ellagic acid that is extracted from the seeds of meeger red raspberries will

be hundreds of times stronger. Listen to these testimonials 512 512

404-2331

and also see this letter that I am sending to Oncologists.

Take care,

Steve

x-no-archive: yes

To all Oncologist's:

The Hollings Cancer instititute at the University of South Carolina

is doing a double blind study on a large group of 500 cervical cancer

patients that has everyone excited. They are excited because

their past nine years of study have shown that a natural product

called ellagic acid is causing G-arrest within 48 hours (inhibiting and

stopping mitosis-cancer cell division), and apoptosis (normal cell

death) within 72 hours, for breast, pancreas, esophageal, skin, colon

and prostate cancer cells. Clinical tests also show that ellagic

acid prevents the destruction of the p53 gene by cancer cells.

Additional studies suggest that one of the mechanisms by which

ellagic acid inhibits mutagenesis and carcinogenesis is by forming

adducts with DNA, thus masking binding sites to be occupied by the

mutagen or carcinogen.

Ellagic acid can be found in different foods, but the clinic has identified

the red raspberry as having the highest content of the acid. Moreover, the

doctors at Holling's have created a patent pending process of extracting

potent levels of the acid from the seeds of the raspberrys that are getting

dramatic results results. Other USA sources substantiate the Hollings

Cancer Institute include:

Department of Surgical Oncology, College of Medicine, University of

Illinois at Chicago, Illinois; Division of Environmental Health Sciences,

The Ohio State University School of Public Health, Colombus, Ohio;

Departmant of Medicine, Lakeside Veterans Affairs Medical Center,

Northwestern University School of Medicine, Stanford, CA; Department

of Preventative Medicine, Ohio State University, Colombus, Ohio.

Here is a description of the study which came from a website of the

Washington Raspberry Commission. You can see the Hollings research

articles there.

http://www.red-raspberry.com/

Here are some notes from the site. Reprinted by permission from WRC

" The proposed study, under the direction of Nixon, M.D., President of

the American Health Foundation and Drs. Dave Gangemi and Blair Holliday of

the

Hollings Cancer Center/Medical University of South Carolina, will evaluate

women with atypical squamous cells of undetermined significance (ASCUS) in

which there is neither treatment nor clinical evaluation available. ASCUS

represents as much as 10% of all Papanicolaou smears in the US and

represents

approximately 5 million females. In this population, these women who are

infected with human papillomaviruses (HPV) types 16 and/or 18 are at the

greatest risk of developing cervical cancer at some stage in their lives. In

addition, women who are diagnosed with the immature metaplastic form of

ASCUS

usually have lesions which are higher in the endocervical canal, are more

metabolically active, have flatter surface areas, and are more likely to

invade

the underlying connective tissue as well as the endocervical glandular

epithelium. This population represents approximately one million women in

the

United States alone. The condition is very pronounced in countries outside

the

United States. In India this is one of the two major cancers affecting

women. "

Research sources:

Cancer Lett 1999 Mar 1 1;136(2):215-21

Expression and its posssible role in G1 arrest and apoptosisi in ellagic

acid treated cancer cells.

Narayanan BA, Geoffroy O, Wilmington MC, Re GG, Nixon DWCANCER P

Prevention program, Hollings Cancer Center, Medical University of South

Carolina, ton 29425, USA.

" Ellagia acid is a phenolic compound present in fruits and nuts including

raspberries, strawberries and walnuts. It is known to inhibit certain

carcinogen-induced cancers and may have other chemopreventive

properties. The effects of ellagic acid on cell cycle events and apoptosis

were studied in cervical carcinoma (CaSki) cells. We found that ellagic

acid at a concentration of 10(-5) M induced G arrest within 48 h, inhibited

overall cell growth and induced apoptosis in CaSki cells after 72 h of

treatment. Activation of the cdk inhibitory protein p21 by ellagic acid

suggests a role for ellagic acin in cell cycle regulation of cancer cells. "

Focus: To Evaluate Red Raspberry Ellagic Acid in Prevention of Cervical

Cancer

There is now clinical evidence to suggest that ellagic acid concentrations

at

tissue sites such as the cervix may be obtained with the oral administration

of

red raspberries. This belief comes from bioavailability studies in which

human

volunteers have ingested raspberry puree. Because of this and observations

in

human volunteers ingesting daily quantities of raspberry puree for

prevention

of colon cancer, a clinical trial will examine ellagic acid from raspberries

in

prevention of pre-cancerous cervical lesions developing into a malignant

condition.

The proposed study, under the direction of Nixon, M.D., President of

the

American Health Foundation and Drs. Dave Gangemi and Blair Holliday of the

Hollings Cancer Center/Medical University of South Carolina, will evaluate

women with atypical squamous cells of undetermined significance (ASCUS) in

which there is neither treatment nor clinical evaluation available. ASCUS

represents as much as 10% of all Papanicolaou smears in the US and

represents

approximately 5 million females. In this population, these women who are

infected with human papillomaviruses (HPV) types 16 and/or 18 are at the

greatest risk of developing cervical cancer at some stage in their lives. In

addition, women who are diagnosed with the immature metaplastic form of

ASCUS

usually have lesions which are higher in the endocervical canal, are more

metabolically active, have flatter surface areas, and are more likely to

invade

the underlying connective tissue as well as the endocervical glandular

epithelium. This population represents approximately one million women in

the

United States alone. The condition is very pronounced in countries outside

the

United States. In India this is one of the two major cancers affecting

women.

One way to evaluate the potential progression rate in these individuals is

to

monitor the levels of viral oncogene (E6/E7) messenger RNA expression in

cervical tissue. The study with evaluate women with ASCUS who have little or

no

viral oncogene expression with those who have relatively elevated levels of

HPV

oncogene expression.

The Study Approach & Red Raspberry Dosage

The approach will orally administer ellagic acid (using red raspberry puree,

the primary whole foods source of ellagic acid) at dosages providing

detactable

tissue levels in the cervix (Phase I of proposed study) over a two-year

period

(Phase II). Women in the study (to commence 1999-2000) will be carefully

evaluated for any potential adverse effects of treatment and their E6/E7

levels

carefully monitored every three months. Women receiving treatment will then

undergo a full clinical evaluation at the end of the two-year trial period

and

changes in the levels of oncogene expression and in cervical pathology

determined. Changes in women receiving the red raspberry dosage will be

compared to changes in women receiving a placebo.

A biostatistician will evaluate the group sizes needed to determine a

statistically significant change in ASCUS progression following ellagic acid

(red raspberry) ingestion. Preliminary estimates indicate that five hundred

women will be needed for the generation of valid predictions. Volunteers

will

be recruited from the MUSC Cancer Center Access Network, Clinics and the

State

Department of Health and Environmental Control. Entry will be based on

pathological and cytological conditions discussed herein. Individuals will

be

divided into low and high HPV oncogene expression groups and each group

further

divided into ellagic acid and placebo groups.

Phase I Study

In Phase I, serum levels of ellagic acid will be monitored over a two-month

period. At the end of this time cervical biopsies taken to determine tissue

levels. Highly sensitive analytical techniques utilizing gas chromatographic

mass spectroscopy will be utilized to measure tissue concentrations. The

results from Phase I will be used to determine compliance rates and the

daily

dosage needed to detect ellagic acid in the cervix.

Phase II Study

In Phase II, cervical swabs will be taken from volunteers will well-defined

cytopathological changes and the cells evaluated for HPV oncogene expression

using a highly sensitive biomarkers assay (reverse transcriptase-polymerase

chain reaction (RT-PCR). Individuals will receive oral dosages (to be

determined from Phase I) of raspberry puree and be reevaluated every three

months to determine the condition of their lesions (progressive, persistent,

or

regressive) using immunocytochemical techniques. Phase II will be a double

blind placebo controlled study in which the research pharmacy laboratory

will

keep the treatment code. At the end of the two year period, date from each

treatment group will be evaluated by a biostatistician and compared to

placebo

groups for changes in the rate of progression to Low Grade Cervical

Intrepithelial Lesions (CINI). Any volunteer progressing to CINI during this

study will be removed and given conventional therapy (colposcopy and biopsy,

laser ablation, or loop excision of the transformation zone)

A barrage of clinical research at Hollings Cancer Center (ton, SC)

confirms that red raspberries, the richest food source of a substance known

as

ellagic acid, inhibits the growth of cancer cells. Studies under the

direction

of Dr. Nixon indicate that daily consumption of 150grams (1 cup) of

red

raspberries slows the growth of abnormal colon cells in humans, prevents (in

some instances destroys) the development of cells infected with human

papilloma

virus (HPV) the cause of cervical cancer, and most recently found to break

down

extracted human leukemia cells.

Dr. Nixon's anti-cancer prowess comes at a time when most Americans seek to

treat medical problems through changes in diet, rather than take medication.

Foods containing significant levels of biologically active components that

impart health benefits beyond basic nutrition when consumed in typical or

optimal serving sizes, are fast-becoming the hot button for consumers. Red

raspberries as the key source of cancer preventive, cancer fighting, and in

some instances cancer cell destroying ellagic acid may be the ultimate

cancer-fighting food today.

Food Sources of Ellagic Acid – micrograms/gm dry wt.

Red Raspberries1500

Strawberries630

Walnuts590

Pecans330

Cranberries120

Ellagic Acid is a naturally occurring phenolic constituent in certain fruits

and nuts. Research in the past decade confirms that ellagic acid markedly

inhibits the ability of other chemicals to cause mutations in bacteria.

Ellagic

acid from red raspberries has proven as an effective antimutagen and

anticarcinogen as well as a inhibitor of cancer.

Misc: research sources:

Protective Effect of Curcumin, Ellagic Acid and Bixin on Radiation Induced

Genotoxicity

K.C. Thresiamma, J. and R. Kuttan Amala Cancer Research Centre, Amala

Nagar, Trichur, India

Induction of micronuclei and chromosomal aberrations produced by whole body

expinduced

inhibition of micronucleated polychromatic and normochromatic erythrocytes,

was

comparable with a-tocopherol (200 µ moles) administration. Curcumin and

ellagic acid were also found to significantly reduce the number of bone

marrow

cells with chromosomal aberrations and chromosomal fragments as effectively

as

a-tocopherol. Moreover, administration of antioxidants inhibited the DNA

strand

breaks produced in rat lymphocytes upon radiation as seen from the DNA

unwinding studies. These results indicated that antioxidant curcumin,

ellagic

acid and bixin provide protection against chromosome damage produced by

radiation.

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[Guest guest]

yes judy GOD is trying to show us the way.......we all need to try and

understand ,im still looking and praying for a brighter future for new

things to help with cancer.....this group is the best ,,,keep up the good

works all of you........pat

[Guest guest]

SANDY. i took grape seed extract pills and still do and

drank grape juice and many other things for my lung cancer ...i have

lived 3 years longer then expected and plan on many more years with the

help of inspireing places such as the group..............pat.

[Guest guest]

who sells the allergic acid ?

[Guest guest]

Allergic Acid? I think you mean Ellagic Acid.

Sold by 21st Century Nutriceuticals..800-638-7462 $50 for 120 tabs

(1 month supply). Best..JR

[Guest guest]

thanx from one jr to another jr