Guest guest Posted June 10, 2001 Report Share Posted June 10, 2001 They have been attempting this POTATO vaccine for several years now.. When the potato is cooked the vaccine is neutrilized... So it did not work in the past. Bananas is the method that they are looking at with more hopeful results.. No one cooks bananas.. ----- Original Message ----- From: Donna Coulter <mommylovesrj@...> Now We Have a Potato Vaccine in The Wings > > > For several years, scientists have been trying to > develop vaccines that are delivered through foods such > as potatoes and tomatoes rather than needles. > > The hope is that edible vaccines may be more practical > for use in developing countries, since the foods do > not need to be refrigerated as ordinary vaccines must, > and the edible vaccines do not require syringes and > other medical equipment. > > > So far, plant-based vaccines have met with limited > success. > > One problem has been figuring out a way to get edible > vaccines into gut tissues without being destroyed by > digestive juices. > > > Researchers got past this obstacle by designing a > vaccine around the cholera toxin, which can latch onto > the lining of the gut without being destroyed by > digestive juices. Normally the ability of the toxin to > survive in the gut has harmful consequences, leading > to cholera, but the researchers were able to use the > toxin without causing disease. > > > Investigators took bits of the cholera toxin and > joined them with proteins, or antigens, from two other > infectious pathogens that invade the gastrointestinal > tract--rotavirus and a strain of E. coli bacteria. > They then developed a genetically modified potato that > contained the triple combination. > > > The approach seems to work as the investigators found > that female mice that ate the genetically modified > potatoes developed antibodies to all three microbes. > > > Nature Biotechnology June 2001;19:548-552 Quote Link to comment Share on other sites More sharing options...
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