Re: Personal Survey/Announcement

[Guest guest]

In a message dated 3/23/01 8:40:43 AM Eastern Standard Time,

DownsIsUp@... writes:

> I know all

> the books and professionals say that I have a 50/50 chance of having

> another

>

I was told by the geneticists that I had a 1 in 100 chance of having another

baby with DS until I reached an age where the odds were greater.

I know of one family that had a second baby with Trisomy 21 (not

translocation) in all the families I know in our area.

[Guest guest]

Congratulations on your pregnancy!

My first pregnancy resulted in my son (now 3.5 years old) who has DS. I then

had a miscarriage (s Syndrome). And just 5 1/2 months ago gave birth

to a beautiful baby girl (no DS). My AFP bloodtest came back with results

that put the risk of having a baby with DS at the same level it was for my

age. Which is 38. So my risk was the same as for any 38 year old pregnant

woman. We decided against amnio. Our reasons being that we did not want to

do anything that could result in a miscarriage or a preterm baby. We would

let her bake as long as possible to make sure she would be the strongest she

could be when born whatever her diagnosis. During a Level 2 ultra sound the

fold on the back of her neck was in the high end of the normal range. So

that did give us some worry. Because of this, at birth we were able to have

chromosome testing done that confirmed that she is a typical child.

So that is our story. Think positive thoughts! Take care of yourself and

enjoy your pregnancy! Monika

PS Congratulations to Evan too on soon becoming a big brother! It will be a

wonderful experience for him!

[Guest guest]

Congratulations!

We have been so blessed! Our first son, second child, was born in 1981

with DS and died shortly before his 4th birthday from airway problems and

surgical complications. In 1983 and 1988 we had two nda daughters, but

several miscarriages in the attempt. Because of the repeated miscarriages,

we had genetic testing done on ourselves (parents) and nothing irregular

was found. In 1990, we were surprised by another pregnancy. We were told

that due to reproductive history and age, our chance of having another

child with DS was 1 in 20. We chose not to have any testing done on the

baby, and in April, 1991, Danny (now 9, DS) was born.

The choice to go ahead with Danny's pregnancy without prenatal testing

was an easy on for us. Still, as you can see, we have not been faced with

raising two children with DS simultaneously.

Bev

----------

From: DownsIsUp@...

I am mostly a " dedicated lurker, " but I now have a question. I am

wondering

how many families on this list actually have been " blessed " with the birth

of

more than one baby being born into their family with Down syndrome?

[Guest guest]

Terry,

Congrats!!! One child with DS age 10 1/2 and one without age 6. When I was

pregnant with , my six year old, my husband and I were discussing many

times how it would be a good thing if we had another child with DS- after all

we were informed, knew what to expect (sorta) ad many other pointers.

I did have amnio though. I was also 37 when I got pregnant with jesse. Let

me tell you- he is a handful!!!!!! But I love them both different!

[Guest guest]

We had two children when Jess was born; one does have a processing deficit,

but that may have been due to infections. A son, , was stillborn

following amnio between Jess and Duncan (nda), but had no chromosomal or

other defects.

Our geneticist told us after Jess was born that our " risk factor " was 1 in

100 (pretty much the same as similar age group) until I was--I mean get to

be! ;o)--40, but went up sharply after that.

My understanding is that is the risk factor when the child with ds has the

commonest form (translocation) and that when a translocation or mosaic form

exists the risk is higher.

I used to know a mom who had had two children with ds--other kids too, I

think. Each had a different type--I think it was mosaic then common

translocation.

Judi

Re: Personal Survey/Announcement

In a message dated 3/23/01 8:40:43 AM Eastern Standard Time,

DownsIsUp@... writes:

> I know all

> the books and professionals say that I have a 50/50 chance of having

> another

>

I was told by the geneticists that I had a 1 in 100 chance of having another

baby with DS until I reached an age where the odds were greater.

I know of one family that had a second baby with Trisomy 21 (not

translocation) in all the families I know in our area.

[Guest guest]

Hey Terry!

Congratulations! Great news.

The annual Day at the River is tentatively scheduled for

May 5th. A newsletter will go out soon.

Sharon

> Hi Everyone:

>

> I am mostly a " dedicated lurker, " but I now have a question. I am wondering

> how many families on this list actually have been " blessed " with the birth of

> more than one baby being born into their family with Down syndrome?

>

> If you haven't guessed, yep, I just found out that I'm expecting! I know all

> the books and professionals say that I have a 50/50 chance of having another

> baby with Down syndrome, but I am just wondering if it has actually happened

> to anyone on this list?

>

> Thanks in advance.

>

> Terry Curtis

> Mom to Evan, 5, DS

>

>

>

[Guest guest]

Within our community here in So Cal... I met a mother of twins (both with

DS). I was unable to find out which brand... but my guess would be which

ever one is carried from family to family.

This may not match exactly what you are looking for and I consider it a

fluke but my son has a blood cousin who also has DS... I always thought that

was strange... both of them have the " oops " kind...

[Guest guest]

What day at the river????

The annual Day at the River is tentatively scheduled for

May 5th. A newsletter will go out soon.

[Guest guest]

Terry

Lyndara was my first and she had downs and we were told that we had a 1 in

100 chance of having another downs child. I had 2 children after her and

neither of them had downs. I thought 1 in a 100 were good odds and didn't

hesitate about trying again. Patty

[Guest guest]

In a message dated 3/23/01 2:35:11 PM Central Standard Time,

lowenthalrj@... writes:

> My understanding is that is the risk factor when the child with ds has the

> commonest form (translocation) and that when a translocation or mosaic form

> exists the risk is higher.

>

> I used to know a mom who had had two children with ds--other kids too, I

> think. Each had a different type--I think it was mosaic then common

> translocation.

>

> Judi

>

Actually, Judi, the commonest form is Trisomy 21. Translocation is

much rarer and may or may not be hereditary. If it is hereditary then the

risk of course, is much higher. I have a cousin who has 2 kids with DS but

we have the hereditary kind. I do know one other family who has 2 and they

are trisomy 21. Jessie

[Guest guest]

You are right--mind was not connected to fingers for a few moments! It's

nondisjunctional trisomy as most common, with mosaic and translocational as

the two less common forms that are possible hereditary forms.

gosh, is it nondisjunctional or am I remembering something else? I think I

have run out of virtual memory here, like my puter keeps griping about! ;o)

Judi

Re: Personal Survey/Announcement

In a message dated 3/23/01 2:35:11 PM Central Standard Time,

lowenthalrj@... writes:

My understanding is that is the risk factor when the child with ds has

the

commonest form (translocation) and that when a translocation or mosaic

form

exists the risk is higher.

I used to know a mom who had had two children with ds--other kids too, I

think. Each had a different type--I think it was mosaic then common

translocation.

Judi

Actually, Judi, the commonest form is Trisomy 21. Translocation is

much rarer and may or may not be hereditary. If it is hereditary then the

risk of course, is much higher. I have a cousin who has 2 kids with DS

but

we have the hereditary kind. I do know one other family who has 2 and

they

are trisomy 21. Jessie

[Guest guest]

All forms of DS are Trisomy 21, which just means three 21 chromosomes.

Non-disjunction is the most common and is the one that is just a fluke, no

heredity involved. Translocation is uch less common, about 2 - 3 percent I

think? If a child has a translocation (this means the third 21 chromosome

is stuck to another chromosome, in my case is is the 14th chrom.), then

there is a chance that one of the parents are carriers. Mosaic DS is the

least common.

R.

Mom to (6, ds) and Grace (3)

> Actually, Judi, the commonest form is Trisomy 21. Translocation is

> much rarer and may or may not be hereditary. If it is hereditary then the

> risk of course, is much higher. I have a cousin who has 2 kids with DS

but

> we have the hereditary kind. I do know one other family who has 2 and

they

> are trisomy 21. Jessie