Too much T4 can be stored in cells and released to produce toxicity?

[Guest guest]

I was reading last night and came across a reference that T4 taken when T3 is

what's needed can be stored in the cells and released at a later time to produce

a very toxic feeling. I've been having some very toxic spells and am wondering

if this could be what is happening.

I was on armor/naturethroid for maybe 12-14 years. In January of 2011 I had an

episode of what might have been hyperthyroid or a super adrenal crash or

something intense. AFTER that episode I could tolerate NO naturethroid at all.

Even 1/8 of a grain brought on horrible unwell feeling - like the start of

another episode like the first.

I went for probably six months trying every so often 1/8 tablet, usually same

results.

New doc tested my RT3 and thought it indicated I needed straight T3. Have been

on straight T3 for maybe three months, very gradually raising levels. I went to

him because I had started to feel this awful 'toxic' feeling - hard to breathe,

felt like I was suffocating, like I'd been poisoned.

He upped my cortisol first from 12.5mg to 20mg and I felt immediately better for

those couple of weeks, then we started the T3 and I've had a little hard time

acclimating to it. Anyway I've just lately had more of that toxic feeling. I

am wondering if I could be NOW releasing T4? I mean, how long will it stay

stored in my cells? Does the available T3 allow it to be released?

This could be anything. I am experimenting today with no dairy, my primary

source of fat, thinking I may have developed an allergy to it. If I am detoxing

whatever, that's good and I'll soldier on through it. I'd just like to know so

I can know how to help myself!

Also is there a downloadable version of Dr. P's book on T3? Either audio or a

pdf?

Thanks for any thoughts or suggestions!

[Guest guest]

Dr Peatfield's book is not just about T3, it is about the

diagnosing and correct treatment of those with symptoms of hypothyroidism and

associated conditions. There is not a downloadable version of his book on the

Internet, but our TPA library has a copy which we can send to you for the cost

of posting, which you can send to me if you would like to borrow it for a

while. This is the same with 's Book 'Recovering with T3'. Let me

know if borrowing either of these is of interest to you and I will send you my

home address so you can send me stamps and I will be happy to send either one

(or both) out to you.

Check out the associated conditions listed below that can stop

thyroid hormone from working to see whether any of these could be the cause of

your problem.

The

main condition responsible for stopping thyroid hormone from working is, quite

simply, a patient’s thyroxine dose is too low because the doctor or

consultant refuses to increase it, because the serum thyroid function test

results appear OK. Sometimes, the thyroxine dose is too high, yet patients

still don't feel well. They continue to suffer. Some reasons for this:

They may be suffering

with low adrenal reserve. The production of T4, its conversion to T3, and the

receptor uptake requires a normal amount of adrenal hormones, notably, of

course, cortisone. (Excess cortisone can shut production down, however.) This

is what happens if the adrenals are not responding properly, and provision of

cortisone usually switches it on again. But sometimes it

doesn’t. If the illness has been going on for a long time, the

enzyme seems to fail. This conversion failure (inexplicably denied by

many endocrinologists) means the thyroxine builds up, unconverted. So it

doesn’t work, and T4 toxicosis results. This makes the patient feel quite

unwell, toxic, often with palpitations and chest pain. If provision of adrenal

support doesn’t remedy the situation, the final solution is the use of

the active thyroid hormone, already converted, T3 - either synthetic or

natural.

Then, we have systemic

candidiasis. This is where candida albicans, yeast, which causes skin

infections almost anywhere in the body, invades the lining of the lower part of

the small intestine and the large intestine. Here, the candida sets up

residence in the warmth and the dark, and demands to be fed. Loving

sugars and starches, candida can make you suffer terrible sweet cravings.

Candida can produce toxins which can cause very many symptoms of exhaustion,

headache, general illness, and which interfere with the uptake of thyroid and

adrenal treatment. Sometimes the levels - which we usually test for - can

be very high, and make successful treatment difficult to achieve until

adequately treated.

Then there is receptor

resistance which could be a culprit. Being hypothyroid for some

considerable time may mean the biochemical mechanisms which permit the binding

of T3 to the receptors, is downgraded - so the T3 won’t go in. With

slow build up of T3, with full adrenal support and adequate vitamins and

minerals, the receptors do come on line again. But this can be quite a

slow process, and care has to be taken to build the dose up gradually.

And then there are

Food allergies. The most common food allergy is allergy to gluten, the protein

fraction of wheat. The antibody generated by the body, by a process of

molecular mimicry, cross reacts with the thyroperoxidase enzyme, (which makes

thyroxine) and shuts it down. So allergy to bread can make you hypothyroid.

There may be other food allergies with this kind of effect, but information on

these is scanty. Certainly allergic response to certain foods can affect

adrenal function and imperil thyroid production and uptake.

Then we have hormone

imbalances. The whole of the endocrine system is linked; each part of it needs

the other parts to be operating normally to work properly. An example of

this we have seen already, with cortisone. But another example is the

operation of sex hormones. The imbalance that occurs at the menopause

with progesterone running down, and a relative dominance of oestrogen is a

further case in point – oestrogen dominance downgrades production,

transportation and uptake of thyroid hormones. This is why hypothyroidism

may first appear at the menopause; the symptoms ascribed to this alone, which

is then treated – often with extra oestrogen, making the whole thing

worse. Deficiency in progesterone most especially needs to be dealt with,

since it reverses oestrogen dominance, improves many menopausal symptoms like

sweats and mood swings, and reverses osteoporosis. Happily natural

progesterone cream is easily obtained: when used it has the added benefit of

helping to stabilise adrenal function.

Then, we must never

forget the possibility of mercury poisoning (through amalgam fillings) - low

levels of iron, transferring saturation%, ferritin, vitamin B12, vitamin D3,

magnesium, folate, copper and zinc - all of which, if low, stop the thyroid

hormone from being utilised by the cells - these have to be treated.

As Dr Peatfield says

" When you have been quite unwell for a long time, all these problems have

to be dealt with; and since each may affect the other, it all has to be done

rather carefully.

Contrary

to cherished beliefs by much of the medical establishment, the correction of a

thyroid deficiency state has a number of complexities and variables, which make

the treatment usually quite specific for each person. The balancing of

these variables is as much up to you as to your doctor– which is why a

check of morning, day and evening temperatures and pulse rates, together with

symptoms, good and bad, can be so helpful.

Luv

- Sheila

I was reading last night and came across a

reference that T4 taken when T3 is what's needed can be stored in the cells and

released at a later time to produce a very toxic feeling. I've been having some

very toxic spells and am wondering if this could be what is happening.

Also is there a downloadable version of Dr. P's book on T3? Either audio or a

pdf?

Thanks for any thoughts or suggestions!

[Guest guest]

I would love to borrow them. I am stateside, though, does that make a

difference? I am a quick reader, if it matters. Shall I contact you off list?

Terijo

[Guest guest]

You would need to find the what the cost of sending the two

books from the UK would be to you, and because you live in the US, rather than

sending stamps for the cost of postage, make a payment into our Paypal account info@... and when I receive it,

I will send the book(s) to you. The books weigh as follows

'Your Thyroid and How to Keep it Healthy' Dr Barry Peatfield 514

grms:

'Recovering with T3' - 565 grms.

You would need to include the cost of a jiffy bag too.

Contacting me off list would be better [sheila@...]

Luv - Sheila

I would love to borrow them. I am stateside, though, does that make a

difference? I am a quick reader, if it matters. Shall I contact you off list?

Terijo

[Guest guest]

Hi,

As it would be quite costly to post to the USA, it is possible to buy Dr

Peatfield's book from Amazon.com

http://www.amazon.com/Your-Thyroid-How-Keep-Healthy/dp/190514010X for $29 or

secondhand for about $20 including postage. 's book is $24.95 new.

Dr Peatfield's book is also available on Abe Books for about $15 plus postage

within the USA :

Your Thyroid And How To Keep It Healthy

Durrant-Peatfield, Barry; Durrant-Peatfie, Barry

Bookseller: SuperBookDeals

(South Bend, IN, U.S.A.)

Bookseller Rating:

Quantity Available: 10

ISBN: 190514010X / 1-905140-10-X

Kind regards,

Margaret

>

>

> 'Your Thyroid and How to Keep it Healthy' Dr Barry Peatfield 514 grms:

>

> 'Recovering with T3' - 565 grms.

>

> You would need to include the cost of a jiffy bag too.

>

> Contacting me off list would be better [sheila@...]

>

> Luv - Sheila

>

>

>

>

>

>

>

>

> I would love to borrow them. I am stateside, though, does that make a

> difference? I am a quick reader, if it matters. Shall I contact you off

> list? Terijo

>