Guest guest Posted December 13, 2011 Report Share Posted December 13, 2011 OK...what shall I do now? Had tests prior to starting my Cynomel from Mexico - which I am feeling good on. I was expecting my T3 to be low but it was 5.1 (ref 2.6 - 5.7). Like I say this was based on 100mg T4 only and I did not take any on the morning of the test. My T4 was 16.3 TSH 0.74. BUT my ferritin is still really low (forgot to get levels) but GP phoned to tell me. Ive been on liquid iron for 3mths after getting nowhere with tablets. But it seems the liquid iron isnt working. So....anyone know whats going on? I need to double my iron daily. Should I still continue with my reduced T4 (.75) and 25mg split in 2 daily??? Could the low ferritin affect my thyroid function even if the levels are good?? Just dont know whats going on. Im thinking continue as I am with the T3 and get retested in January when I see the specialist? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 13, 2011 Report Share Posted December 13, 2011 Low iron, transferrin saturation%, ferritin and B12 can affect thyroid uptake very much. Read just some of the research and studies that have been done regarding low levels of specific vitamins and minerals to show how low levels can stop the thyroid hormone from being properly utilised at the cellular level: Low iron/ferritin: Iron deficiency is shown to significantly reduce T4 to T3 conversion, increase reverse T3 levels, and block the thermogenic (metabolism boosting) properties of thyroid hormone (1-4). Thus, iron deficiency, as indicated by an iron saturation below 25 or a ferritin below 70, will result in diminished intracellular T3 levels. Additionally, T4 should not be considered adequate thyroid replacement if iron deficiency is present (1-4)). 1. Dillman E, Gale C, Green W, et al. Hypothermia in iron deficiency due to altered triiodithyroidine metabolism. Regulatory, Integrative and Comparative Physiology 1980;239(5):377-R381. 2. SM, PE, Lukaski HC. In vitro hepatic thyroid hormone deiodination in iron-deficient rats: effect of dietary fat. Life Sci 1993;53(8):603-9. 3. Zimmermann MB, Köhrle J. The Impact of Iron and Selenium Deficiencies on Iodine and Thyroid Metabolism: Biochemistry and Relevance to Public Health. Thyroid 2002;12(10): 867-78. 4. Beard J, tobin B, Green W. Evidence for Thyroid Hormone Deficiency in Iron-Deficient Anemic Rats. J. Nutr. 1989;119:772-778. Low vitamin B12: http://www.ncbi.nlm.nih.gov/pubmed/18655403 Low vitamin D3: http://www.eje-online.org/cgi/content/abstract/113/3/329 and http://www.goodhormonehealth.com/VitaminD.pdf Low magnesium: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC292768/pdf/jcinvest00264-0105.pdf Low folate: http://www.clinchem.org/cgi/content/full/47/9/1738 and http://www.liebertonline.com/doi/abs/10.1089/thy.1999.9.1163 Low copper http://www.ithyroid.com/copper.htm http://www.drlwilson.com/articles/copper_toxicity_syndrome.htm http://www.ithyroid.com/copper.htm http://www.rjpbcs.com/pdf/2011_2(2)/68.pdf http://ajplegacy.physiology.org/content/171/3/652.extract Low zinc:http://www.istanbul.edu.tr/ffdbiyo/current4/07%20Iham%20AM%C4%B0R.pdf and http://articles.webraydian.com/article1648-Role_of_Zinc_and_Copper_in_Effective_Thyroid_Function.html You may find that your GP needs to try you on different forms of elemental iron until one is found that you can properly absorb. Are you taking high doses of vitamin C with the iron, i.e. 3/4000mgs daily? Some people need to take iron three times daily, but the problem is that you must never take iron and thyroid hormone within four hours of each other. How have you been taking yours? Luv - Sheila So....anyone know whats going on? I need to double my iron daily. Should I still continue with my reduced T4 (.75) and 25mg split in 2 daily??? Could the low ferritin affect my thyroid function even if the levels are good?? Just dont know whats going on. Im thinking continue as I am with the T3 and get retested in January when I see the specialist? 1 of 1 File(s) MINERALS AND VIT. TESTING.doc Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 13, 2011 Report Share Posted December 13, 2011 do you know what your copper level is? do you know what your zinc level is? both these are needed for proper utilisation of iron ...as is magnesium. i think these days it is recommedned to have a full set of iron tests done in order to determine whether you need to supplement or not. have you been tested for heliobacter? ...apparenty that can often be implicated in low ferritin levels. another thing is there is a *pay back* system regarding low iron status...i forget exactly how it works but something along the lines of iron is returned to the bone marrow first ...sometimes ferritin initially drops with supplementation due to this *pay back* system. too much iron is damaging (you rust from the inside!) trish > > OK...what shall I do now? > BUT my ferritin is still really low (forgot to get levels) but GP phoned to tell me. > > Ive been on liquid iron for 3mths after getting nowhere with tablets. But it seems the liquid iron isnt working. > > So....anyone know whats going on? I need to double my iron daily. > > Should I still continue with my reduced T4 (.75) and 25mg split in 2 daily??? > > Could the low ferritin affect my thyroid function even if the levels are good?? > > Just dont know whats going on. Im thinking continue as I am with the T3 and get retested in January when I see the specialist? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 13, 2011 Report Share Posted December 13, 2011 No not had any of those. I shall note it for the endo. Somethings not right. Sounds horrid!! Im starting to feel a bit rusty but think its just working full time, going to college and being mum to a 3 year old!! On Tue, Dec 13, 2011 12:02 PST Trish wrote: > > > >do you know what your copper level is? do you know what your zinc level is? both these are needed for proper utilisation of iron ...as is magnesium. > >i think these days it is recommedned to have a full set of iron tests done in order to determine whether you need to supplement or not. [Ed] Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2011 Report Share Posted December 14, 2011 Hello Hayley You need to ask the endocrinologist to test your levels of iron, transferrin saturation%, ferritin, vitamin B12, vitamin D3, magnesium, folate, copper and zinc, and when these results are returned, post them here on the forum together with the reference range and we will be able to help with their interpretation. Many doctors will tell you that you do not have a problem if such results appear ANYWHERE within the reference range. They are not taught how to read such results or taught about their association with low thyroid levels. Luv - Sheila No not had any of those. I shall note it for the endo. Somethings not right. Sounds horrid!! Im starting to feel a bit rusty but think its just working full time, going to college and being mum to a 3 year old!! On Tue, Dec 13, 2011 12:02 PST Trish wrote: > >do you know what your copper level is? do you know what your zinc level is? both these are needed for proper utilisation of iron ...as is magnesium. > >i think these days it is recommedned to have a full set of iron tests done in order to determine whether you need to supplement or not. [Ed] Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2011 Report Share Posted December 14, 2011 Hayley would you please make sure you erase most of all the previous message/s before you click on reply. I have done it this time but it is very time consuming. Moderator. Have listed everything ready for the 20th Jan. I will be in touch to let you know how appointment goes. Thanks again x On Wed, Dec 14, 2011 00:11 PST Sheila wrote: >Hello Hayley > >You need to ask the endocrinologist to test your levels of iron, transferrin >saturation%, ferritin, vitamin B12, vitamin D3, magnesium, folate, copper >and zinc, and when these results are returned, post them here on the forum >t Quote Link to comment Share on other sites More sharing options...
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