Re: Heart murmur and sub-dural bleed

August 11, 2006

At 09:54 PM 8/10/06 -0800, you wrote:

>I just spent some time at the University of Washington Medical center

>because of a sub-dural bleed. Now after surgery to release the pressure from

>blood on my brain, I'm finally back home in Alaska getting stronger again.

>Although I know exactly when the head pain started, I don't remember hitting

>my head but the doctors think I must have at sometime to start the bleed.

>Before the surgery the anesthesiologist mentioned (assuming I knew)'your

>heart murmur'. I just saw a post from on the other cml group

>about also developing a heart murmur. Any other experience with that? Also

>any experience with bleeds related to Gleevec or CML? Before the bleed, I

>had just gone through 2 months of a 600mg dose of Gleevec when my BCR ABL

>counts increased slightly in Feb.

>Fran from Alaska

>cml, dx 1999, Peg Intron and Ara-c and then Gleevec since 2001

Hi Fran,

Sorry about this medical problem. Gleevec is known of course to cause some

hemorrhages.....it is a known side effect. And several people on different

lists are mentioning 'new' heart murmurs.

I want to encourage you to send a little mini-history to Dr. Druker.....and

also ask his opinion.

I think he will be interested in getting some stories/data on these new

problems that seem to be arising in long term users of IM. Let us know if

you get any feedback from him. I think you probably have his e-mail??? or I

can give it to you.

C.

August 11, 2006

Hey Fran,

I had a heart murmor at diagnosis and from what I understand they are a common

side-effect of CML. As far as the bleeds, I've had a bunch of bruising problems

since I got CML. I bruise fairly easily now. I wonder if the bump to your head

was just a minor bump but because of the CML it bruised easier than it normally

would? Either way I hope you are feeling better soon and that things start

looking up for you!

:}