Re: CML and ulcers

[Guest guest]

Hi Kathy,

Sorry to hear of your problems but welcome to the group anyway.

Gleevec is known to cause low potassium which is also known

as " hypokalemia " . If you look at any of the drug information sheets,

you'll see hypokalemia as a side effect.

As for the ulcers, Gleevec is very hard on the stomach, that's one of

the reasons we're told to take it on a full stomach so I wouldn't be

at all surprised if Gleevec was the cause of your ulcer. I don't know

if they would consider an ulcer a " gastrointestinal hemorrhage " but GI

hemorrhages are documented side effects of Gleevec therapy (you can

find that along with the hypokalemia on any prescribing sheet. Here's

one if you're interested:

http://www.pharma.us.novartis.com/product/pi/pdf/gleevec_tabs.pdf

Take care,

Tracey

>

> Hi Amy gave me this link. I was diagnosed last July 7 that I have

> CML. I am on Gleevec and my white cells are in normal range. I

> recently (3 months ago today) had gastric bypass. I now have an

ulcer

> in my new pouch, having to be given 2 pints of blood last week,

> potassium keeps botttoming out. According to my Oncologist, the

> Gleevec doesn't cause these problems. I never had them until I went

on

> Gleevec. Any information would be appreciated. Thanks, Kathy

>

[Guest guest]

At 05:02 PM 4/9/06 +0000, you wrote:

>Hi Amy gave me this link. I was diagnosed last July 7 that I have

>CML. I am on Gleevec and my white cells are in normal range. I

>recently (3 months ago today) had gastric bypass. I now have an ulcer

>in my new pouch, having to be given 2 pints of blood last week,

>potassium keeps botttoming out. According to my Oncologist, the

>Gleevec doesn't cause these problems. I never had them until I went on

>Gleevec. Any information would be appreciated. Thanks, Kathy

Hi Kathy,

I do believe that some people on Gleevec DO have a problem with low

potassium.....so maybe there is a connection?

I hope everything gets better for you soon.

C.