BMS-354825 Trial (Dasatinib)

March 8, 2006

Hello to all of you,

As some of you are probably aware I am participating in the BMS Trial

and are now in my second week.

I just like to give you some insight into the side effects I am

experiencing since the last week.

Besides the obvious Nausea, Headaches and swelling of facial parts and

the feeling of having a Brick on top of my eyes I also have severe

pain underneath my right ribcase which extented allover my pelvic and

my lower Back including my legs, in particular the right leg.

I went to the Emergency Dept of a known cancer hospital and had a

bloodtest done which did not confirm my fear of acute appendicitis.

An ultrasound of my ovaries did not show any abnormal signs either.

I am still having this pain in my right side underneath the ribcage

and am not fully convinced that it is a side effect of the Drug, but

perhaps an inflammation of the appendix.

Besides all that I am not my usual self but feel weak and lustless.

I do hope that in a few days I do overcome all those " side effects "

and have my life back as it used to be.

If it were not for this " fake " appendix symptoms I could deal with all

the other signs.

I'll be seeing my Doc at the MacCallum Cancer Hospital in

Melbourne by next Tuesday for a big check up.

Folks that's it for today.

I wish you all well and happy!

Ursula

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