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Re: Zero club amd BMT

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Hi Jane and welcome to the club that nobody really wants to be a member

of.

Your side effects were just like mine when I started on Gleevec. It made

me very tired. I thought it would never end, but after about 9 months on

Gleevec, it simply stopped. I keep looking for side effects but can't

find any.

I started the Zero Club the day I started taking Gleevec (it was called

STI572 in the early days). That was in March 2001. Every time that

someone on the list reported that their count was 0/20 via BMB I

assigned them a number. That is how the Zero Club started. In September

2001 I became # 102 in my own club. My most recent entry is # 941 and I

hope to see you join real soon. It is a club of HOPE.

Please do your homework before opting for a BMT. Did you doctor mention

that up to 20% of the patients that undergo a BMT are dead within 12

months from complications of the BMT. Only 50% make it past 5 years.

Zavie

Zavie (age 67)

67 Shoreham Avenue

Ottawa, Canada, dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

PCRU 5/02 at RVH

2.8 log reduction Sep/05

3.0 log reduction Jan/06

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

[ ] Zero club amd BMT

Well thanks for the responses. Nice to feel welcome and also nice

to find others who are at a similar stage to me.

I have 2 questions (so far) ...what is the zero club?

And the next one is longer....

My onncologist and the haemotologist I saw both seem to feel that

because I am " so young " (47 is young?) I should be considering a

Bone Marrow Transplant within a year of diagnosis. My gut is

telling me that if, in a years time, the Gleevec is still doing its

job why should I go through the transplant? When I say this to them

they just shake their heads wisely and tell me they understand why I

should feel that way but Gleevec is not a cure and the BMT is the

only way to go.

Am I being naive to think this way? Especially if I continue to

tolerate the Gleevec well?

By the way, if you are wondering about the weird name..Regent and

Mahogany are my horses. Jane is my own name.

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>

> Well thanks for the responses. Nice to feel welcome and also nice

> to find others who are at a similar stage to me.

>

> I have 2 questions (so far) ...what is the zero club?

>

> And the next one is longer....

>

> My onncologist and the haemotologist I saw both seem to feel that

> because I am " so young " (47 is young?) I should be considering a

> Bone Marrow Transplant within a year of diagnosis. My gut is

> telling me that if, in a years time, the Gleevec is still doing

its

> job why should I go through the transplant? When I say this to

them

> they just shake their heads wisely and tell me they understand why

I

> should feel that way but Gleevec is not a cure and the BMT is the

> only way to go.

>

> Am I being naive to think this way? Especially if I continue to

> tolerate the Gleevec well?

>

> By the way, if you are wondering about the weird name..Regent and

> Mahogany are my horses. Jane is my own name.

>

Hi Jane and once again welcome to the group.

Exactly what zavie says, do your homework before you enter bmt. I

too was diagnosed by a great Oncol. and he also told me because of

my age (42) he said it would be a good idea to have a transplant

within 2 years. Well ive now just passed the 3 year mark and his

mind changes all the time as he said its very promising with the new

drugs coming out. so you need to weigh out the good, the bad and the

evil of bmt. Do research on the new drugs coming out..I dont know

what Africa is like with Meds and how far you are behind America in

getting them, us here in Australia can be up to 3 years...so just do

you homework and i wish you well what ever decision you make..

susie leech

dx 2002

currently of Gleevec

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Hi,

Have to put my 2 cents. I won't tell you not to get a BMT, but I will tell

you to do " ALOT OF RESEARCH " before doing it!!! My doctor in Houston (MD

ANderson) has point blank told me it isn't necessary to have a BMT, stay on the

Gleevec and if anything happens there are other drugs out there that can be

used. I have been on Gleevec for almost 3 years (march 03)..cant believe how

time has flown and have been in remission since july 03, so the odds are good.

Some do well with the BMT, some don't!!! and i think the majority don't from

what i have seen on this board. So, I think a second opinion would be good and

lots of research! Ask Zavie, he will point you into the right direction on

info!!!

Penny

Susie <leechys@...> wrote:

>

> Well thanks for the responses. Nice to feel welcome and also nice

> to find others who are at a similar stage to me.

>

> I have 2 questions (so far) ...what is the zero club?

>

> And the next one is longer....

>

> My onncologist and the haemotologist I saw both seem to feel that

> because I am " so young " (47 is young?) I should be considering a

> Bone Marrow Transplant within a year of diagnosis. My gut is

> telling me that if, in a years time, the Gleevec is still doing

its

> job why should I go through the transplant? When I say this to

them

> they just shake their heads wisely and tell me they understand why

I

> should feel that way but Gleevec is not a cure and the BMT is the

> only way to go.

>

> Am I being naive to think this way? Especially if I continue to

> tolerate the Gleevec well?

>

> By the way, if you are wondering about the weird name..Regent and

> Mahogany are my horses. Jane is my own name.

>

Hi Jane and once again welcome to the group.

Exactly what zavie says, do your homework before you enter bmt. I

too was diagnosed by a great Oncol. and he also told me because of

my age (42) he said it would be a good idea to have a transplant

within 2 years. Well ive now just passed the 3 year mark and his

mind changes all the time as he said its very promising with the new

drugs coming out. so you need to weigh out the good, the bad and the

evil of bmt. Do research on the new drugs coming out..I dont know

what Africa is like with Meds and how far you are behind America in

getting them, us here in Australia can be up to 3 years...so just do

you homework and i wish you well what ever decision you make..

susie leech

dx 2002

currently of Gleevec

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Thanks for the information and the opinions. The reason I am

probing this is that I am the first patient that my oncologist is

treating with Gleevec and the haemotplogist I saw is like the BMT

hero of South Africa. All of which makes me a little sceptical

about the path that they seem to be keen to put me on.

I will go ahead and see if my brother is a match (tests next

Tuesday) and I need to see what impact the Gleevec is having when I

have a Bone Marrow Aspiration in about 2 months time. After that I

may be in a better position to think about this all.

In the meantime, I am going for blood counts and liver function

tests every 14 days (had the first today day14 of Gleevec) and will

get results tomorrow.

Does this sound like a reasonable approach to you guys?

Jane

Dx Nov 05

400mg Glevvec

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Thanks Zavie. Planning on joining the zero club soon!

About this being the club nobody wants to join...a colleague of mine

just died from a brain tumour 4 weeks after diagnosis. After that I

am grateful to be in this club. So much is hopeful actually.

From what I can gather, you are the group oracle ;-)so I take your

advice seriously especially as it is very close to what mu gut is

telling me. At my advanced age (47) I am finally learning to listen

to my gut. Mind you, it is such an enormous one one could hardly

ignore it! Trust me to have to take cancer medication that makes

you GAIN weight! Although even that has not happened to me....yet.

>

> Hi Jane and welcome to the club that nobody really wants to be a

member

> of.

>

> Your side effects were just like mine when I started on Gleevec.

It made

> me very tired. I thought it would never end, but after about 9

months on

> Gleevec, it simply stopped. I keep looking for side effects but

can't

> find any.

>

> I started the Zero Club the day I started taking Gleevec (it was

called

> STI572 in the early days). That was in March 2001. Every time that

> someone on the list reported that their count was 0/20 via BMB I

> assigned them a number. That is how the Zero Club started. In

September

> 2001 I became # 102 in my own club. My most recent entry is # 941

and I

> hope to see you join real soon. It is a club of HOPE.

>

> Please do your homework before opting for a BMT. Did you doctor

mention

> that up to 20% of the patients that undergo a BMT are dead within

12

> months from complications of the BMT. Only 50% make it past 5

years.

>

> Zavie

>

> Zavie (age 67)

> 67 Shoreham Avenue

> Ottawa, Canada, dxd AUG/99

> INF OCT/99 to FEB/00, CHF

> No meds FEB/00 to JAN/01

> Gleevec since MAR/27/01 (400 mg)

> CCR SEP/01. #102 in Zero Club

> PCRU 5/02 at RVH

> 2.8 log reduction Sep/05

> 3.0 log reduction Jan/06

> e-mail: zmiller@...

> Tel: 613-726-1117

> Fax: 309-296-0807

> Cell: 613-202-0204

> ID: zaviem

>

>

> [ ] Zero club amd BMT

>

> Well thanks for the responses. Nice to feel welcome and also nice

> to find others who are at a similar stage to me.

>

> I have 2 questions (so far) ...what is the zero club?

>

> And the next one is longer....

>

> My onncologist and the haemotologist I saw both seem to feel that

> because I am " so young " (47 is young?) I should be considering a

> Bone Marrow Transplant within a year of diagnosis. My gut is

> telling me that if, in a years time, the Gleevec is still doing

its

> job why should I go through the transplant? When I say this to

them

> they just shake their heads wisely and tell me they understand why

I

> should feel that way but Gleevec is not a cure and the BMT is the

> only way to go.

>

> Am I being naive to think this way? Especially if I continue to

> tolerate the Gleevec well?

>

> By the way, if you are wondering about the weird name..Regent and

> Mahogany are my horses. Jane is my own name.

>

>

>

>

>

>

>

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