Re: high blood pressure - Richie

[Guest guest]

Hi Richie,

To my knowledge, marked blood pressure elevations are not known to be caused

by untreated CML, nor a side effect of Gleevec. While it does appear that

Gleevec may lower cardiac risk over time by lowering cholesterol and LDL and

by raising HDL, I wouldn't count on this in the short term; you should get

your hypertension worked up and treated independently.

As others have pointed out, certain types of eye bleeds are an not uncommon

side effect of Gleevec, but what you describe is not the typical side

effect. I'd agree that it's more likely from some other cause especially

since you had an eye bleed with your hypertensive crisis (that's what we

call a BP elevation of that magnitude in the med biz) prior to diagnosis of

CML. If I were you I'd see both an opthalmologist and a blood pressure

specialist. Don't leave this in the hands of your hematologist only.

Good luck,

R (MD)

> Date: Wed, 01 Feb 2006 02:55:23 -0000

> From: " richdpro " <richdpro@...>

> Subject: high blood pressure

>

> Hi has anyone with cml had any radical changes with their blood

> pressure? I had high pressure a long time ago but lost weight and it

> went down. Right before I found out I had cml I started to bleed from

> inside my eyes and my pressure went to 200/120. They gave me Lotrel

> 5/10. Then I was diagnosed with cml and have been taking my prerssure

> all along. It flucates between normal and around 165/87. Has anyone

> else had this problem? My eye cleared up but it happened again on

> Sunday night. I bleed inside my eye. I have be taking my pressure and

> it is still flucating. It almost feels like a sinus infection. Tonight

> it went to 178/100 and again I took it and it was 170/88. What is very

> strange is that before my eye bleeds out (actually you can't see it- it

> is inside my eye in front of my field of vision)I can see crystal

> clear. What should I do and which dr. should I see now? thanks for all

> your help Richie