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Ofatumumab

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Hello everyone

We are back in London from New York The flight back became very eventful as my wife suddenly developed fever 101 F in the morning .

Decided to come in any case, fortunately paracetamol brought it down by the evening and it hasnt come up again.

CLL and fevers seem quite a mystery.

The slides and blocks from India were reveiwed by Prof Mackinnon and it has been verified that the findings of the labs in India which gave the result as small Lymphocytic lymphoma were correct.

It seems the Fish test done when we left London to go to New York has not brought out any thing new.

Now meeting up with Prof Catovsky next week for the treatment plan.

He mailed us about the possibility of using Ofatumumab as one of the pretherapy drugs before the transplant

Does any one have any experience of this?

Past or present personal experience with Ofatumumab would be really welcome and help us in finding out the pros and cons.

Please mail me information about Ofatumumab so we can educate ourselves about it before treatment.

Thank you

Best wishes and good health to all.

from Delhi

Wife diagnosed with CLL in 1997 at age 44,Fish del 13q, unmutated, Zap 70 positive2001 : Chlorambucil partial remmission2002 :RF 6 cycle Tests showed CR after that.Feb 2008 - Oct 2008 RFCcycle 1,2 FC only, cycle 4to 6 RFC cycle 7 Rituximab , cycle 8 Rituximabfinished October 2008Now relapsed since March 2009 - lymph nodes in abdomen, axilla and neck .Diagnosed now as Non Hodgekins Lymphoma - CLL / Small Lymphocytic Lymphoma

Recently diagnosed with AIHA .

Advised BMT/SCT from sister

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