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Prognostic Factors

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,

I typed the www.cllsupport.org.uk/prognostic.htm and I did not get

anything. Usually, when the address is correct is displayed in blue.

Can you tell me what is wrong?

Thank you,

Gisele

>

> You may be interested to read an interesting article on Prognostic

> Factors written specifically for the CLL Support Association in the

UK

> by Dr Pettitt - Reader and Consultant Haematologist at the

> Royal Liverpool University Hospital. The article can be found at:

>

> www.cllsupport.org.uk/prognostic.htm

>

> Regards

>

>

>

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Guest guest

Try http://www.cllsupport.org.uk/prognostic.htm . The http:// part is

usually filled in automatically by the system. You may have an older

version of Windows.

Andy

Re: Prognostic Factors

> ,

>

> I typed the www.cllsupport.org.uk/prognostic.htm and I did not get

> anything. Usually, when the address is correct is displayed in blue.

> Can you tell me what is wrong?

>

> Thank you,

>

> Gisele

>

>

>>

>> You may be interested to read an interesting article on Prognostic

>> Factors written specifically for the CLL Support Association in the

> UK

>> by Dr Pettitt - Reader and Consultant Haematologist at the

>> Royal Liverpool University Hospital. The article can be found at:

>>

>> www.cllsupport.org.uk/prognostic.htm

>>

>> Regards

>>

>>

>>

>

>

>

>

>

>

>

>

>

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Guest guest

Gisele

Please try the link below:

agua33azul@...

Let me know if it still does not work.

Regards

From: [mailto: ] On Behalf Of agua33azul

Sent: 01 August 2006 13:36

Subject: Re: Prognostic

Factors

,

I typed the www.cllsupport.org.uk/prognostic.htm and I did not get

anything. Usually, when the address is correct is displayed in blue.

Can you tell me what is wrong?

Thank you,

Gisele

>

> You may be interested to read an interesting article on Prognostic

> Factors written specifically for the CLL Support Association in the

UK

> by Dr Pettitt - Reader and Consultant Haematologist at the

> Royal Liverpool University

Hospital. The article can

be found at:

>

> www.cllsupport.org.uk/prognostic.htm

>

> Regards

>

>

>

--

No virus found in this incoming message.

Checked by AVG Free Edition.

Version: 7.1.394 / Virus Database: 268.10.5/404 - Release Date: 31/07/2006

--

No virus found in this outgoing message.

Checked by AVG Free Edition.

Version: 7.1.394 / Virus Database: 268.10.5/404 - Release Date: 31/07/2006

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Guest guest

Address works when you google it.

>From: " Gach " <unclewolf@...>

>Reply-

>< >

>Subject: Re: Re: Prognostic Factors

>Date: Tue, 1 Aug 2006 05:46:43 -0700

>

>Try http://www.cllsupport.org.uk/prognostic.htm . The http:// part is

>usually filled in automatically by the system. You may have an older

>version of Windows.

>

>Andy

>

> Re: Prognostic Factors

>

>

> > ,

> >

> > I typed the www.cllsupport.org.uk/prognostic.htm and I did not get

> > anything. Usually, when the address is correct is displayed in blue.

> > Can you tell me what is wrong?

> >

> > Thank you,

> >

> > Gisele

> >

> >

> >>

> >> You may be interested to read an interesting article on Prognostic

> >> Factors written specifically for the CLL Support Association in the

> > UK

> >> by Dr Pettitt - Reader and Consultant Haematologist at the

> >> Royal Liverpool University Hospital. The article can be found at:

> >>

> >> www.cllsupport.org.uk/prognostic.htm

> >>

> >> Regards

> >>

> >>

> >>

> >

> >

> >

> >

> >

> >

> >

> >

> >

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Guest guest

Andy,

Thank you, this time it worked.

Gisele

> >>

> >> You may be interested to read an interesting article on

Prognostic

> >> Factors written specifically for the CLL Support Association in

the

> > UK

> >> by Dr Pettitt - Reader and Consultant Haematologist at the

> >> Royal Liverpool University Hospital. The article can be found

at:

> >>

> >> www.cllsupport.org.uk/prognostic.htm

> >>

> >> Regards

> >>

> >>

> >>

> >

> >

> >

> >

> >

> >

> >

> >

> >

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  • 4 years later...
Guest guest

As it turns out, I just gave a talk today on this subject.

Some patients and physicians like to know what the future might hold. I believe

that the prognostic markers are only good for telling patients what curve they

will be on, not where on the curve they will be, and are therefore not helpful.

Ultimately, these prognostic markers teach us a great deal regarding the biology

of CLL and may help identify better treatments.

For example, one group has shown that the chemokine CLL3 has a strong prognostic

role in CLL. As it turns out, CCL3 signals through the JAK2 kinase. We will be

shortly taking an inhibitor of the JAK2 kinase into the clinic. This will

provide some rationale for its use in CLL.

The one area where prognostic markers are helpful for clinical decision making

is with deletion 17p and deletion 11q and guiding choice of therapy,

Rick Furman, MD

>

> I keep reading that prognostic factors are not useful except in very

> selective circumstances.

>

> Why, then, is so much research time, effort & money spent on developing

> and studying them?

>

> Mal

>

>

>

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