Guest guest Posted January 2, 2007 Report Share Posted January 2, 2007 Barbara - I checked and am told that there was an earlier (late 80s), not very successful, attempt to have an antibody for CD19. Right now we have Rituxan and Humax for CD20, the new one I posted about for CD23, Campath for CD52, and a new, promising one (LL1) in the pipe for CD74. But there is a LOT of work going on, focusing on CDs expressed by CLL patients. Also, see the following comment from our Med. Adv.: It is not just about what markers the cell expresses, but about what happens when the antibody binds the cells. CD19 mAb have been around for quite a while. I remember doing a series of studies in the early 1990s with them which were negative. From a therapeutical standpoint, CLLers should be following the CD40 mAbs (Seattle Genetics and Novartis/Chiron), Humax-CD20, anti-CD23, Hu-1D10, and a new one LL1 against CD74 which is going to open here shortly. Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.