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Here is a pre-Halloween doom & gloomer posted by Dr. Hamblin on the Acor list on Fri. Sept. 15 (my comments in itallics). Not for the-faint-of heart. First the bad news: "the idea of ealy tx. studies is that you can now pick out from marker studies those patients that will eventually need tx. (as in me with poor prognostic markers). For this group it might be that tx. with curative intent could succeed while the bulk of the disease is small (as in me still in stage 2); yet is doomed to failure by the time the bulk increases (as kinda in me trying to dodge the bulk increase so far with Rituxan mono tx.) sufficiently for the disease to become symptomatic." Now for the good news (as if there ever is any): "it is an hypothesis that should be tested with a clinical trial." Open for discussion. Be well. Hal Skye.

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Hey Hal,

Honestly you crack me up, your almost as bad as I am. Where is the answer, well I'll tell you. Were all going to die from this crap ! All the stuff inbetween simply helps us try to determine which treatment will buy us the most time. At least thats the way I look at it. So, What is the best treatment ? and when should you take the treatment and how much? Hahahahaha

Wish I knew, K.

-------------- Original message -------------- From: "Hal Skye" <HALSKYE@...>

Here is a pre-Halloween doom & gloomer posted by Dr. Hamblin on the Acor list on Fri. Sept. 15 (my comments in itallics). Not for the-faint-of heart. First the bad news: "the idea of ealy tx. studies is that you can now pick out from marker studies those patients that will eventually need tx. (as in me with poor prognostic markers). For this group it might be that tx. with curative intent could succeed while the bulk of the disease is small (as in me still in stage 2); yet is doomed to failure by the time the bulk increases (as kinda in me trying to dodge the bulk increase so far with Rituxan mono tx.) sufficiently for the disease to become symptomatic." Now for the good news (as if there ever is any): "it is an hypothesis that should be tested with a clinical trial." Open for discussion. Be well. Hal Skye.

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Kurt,

I don't think all of us will die from this crap. There were will be people who'll get run over by a beer truck.

:-{{ Andy

-- Re: when to treat

Hey Hal,

Honestly you crack me up, your almost as bad as I am. Where is the answer, well I'll tell you. Were all going to die from this crap ! All the stuff inbetween simply helps us try to determine which treatment will buy us the most time. At least thats the way I look at it. So, What is the best treatment ? and when should you take the treatment and how much? Hahahahaha

Wish I knew, K.

-------------- Original message -------------- From: "Hal Skye" <HALSKYE@...>

Here is a pre-Halloween doom & gloomer posted by Dr. Hamblin on the Acor list on Fri. Sept. 15 (my comments in itallics). Not for the-faint-of heart. First the bad news: "the idea of ealy tx. studies is that you can now pick out from marker studies those patients that will eventually need tx. (as in me with poor prognostic markers). For this group it might be that tx. with curative intent could succeed while the bulk of the disease is small (as in me still in stage 2); yet is doomed to failure by the time the bulk increases (as kinda in me trying to dodge the bulk increase so far with Rituxan mono tx.) sufficiently for the disease to become symptomatic." Now for the good news (as if there ever is any): "it is an hypothesis that should be tested with a clinical trial." Open for discussion. Be well. Hal Skye.

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