Guest guest Posted March 18, 2009 Report Share Posted March 18, 2009 Vincristine is a very strong chemo agent and has the reputation of frequently causing neuropathy in feet and hands—which doesn't always go away ... everything's a trade-off, I guess. -Ellen D. On Mar 18, 2009, at 4:05 PM, rrfman wrote: > Let me clarify what I previous said. I do not use vincristine for the > treatment of CLL, but it can be helpful with an autoimmune hemolytic > anemia. Usually the steroids/rituximab are sufficient. If not, > cyclophosphamide is often my next treatment of choice. > > > > > > > > > > > > > > > > > > > > > > > > > > Dear Dr Furman, > > > > > > > > Thanks so much for your response last week to my questions of > progression of txs for AIHA. To be more specific, if someone has had a > course of prednisone (raised the Hg quite well but then dropped after > cessation of tx); then a standard course of Rituxan (worked wonders > for nodes & wbcs, but not rbcs); followed a few months later by > another course of prednisone (again wihch raised Hg quite nicely). But > tapering down to alternating days of 10mg/2.5mg, the retic count has > gone from 60/2.8 to 28/1.2 & LDH from 133 to 164, spleen from 1 to > 5cm. The onc says " decreased red cell production rather than > hemolysis " , but it seems to be both to me? BMB showed >90% involvement > last Aug. > > > > > > > > Could you also comment on next likely treatment? What is your > opinion of RCD vs RCVP vs HDMP+R for AIHA plus impacted BM? Would you > also comment on O'Brien's high-dose R tx for AIHA? Any other > options? > > > > > > > > Your responses are much appreciated. > > > > Marcia in Ca dx'd 2000 > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.