Guest guest Posted August 21, 2010 Report Share Posted August 21, 2010 Can one say that a positive ZAP-70 and a positive CD38 would be an equivalent prognostic indicator to being unmutated? In a message dated 8/21/2010 3:04:45 P.M. Eastern Daylight Time, rrfurman@... writes: IgVH mutational analysis can be obtained from commercial labs such as Quest and Genzyme.> > > > >> > > > Here are some Cytogenics and Immunophenotyping test results prior to> > possible treatment.> > > > Deleted: 11q14.3> > Normal 11q22.3, 13q34, CEP12, 17p13.1> > CD38+ 59%> > ZAP70+ 10%> > IGvH ?> > > > Could someone tell me (or give me recent layman's references for)> > ....> > a) how these results affect the choice of any first line treatment> > that I will need, and> > how these results effect the speed with which CLL will develop.> > > > Oliver Kurer> > > > > > Blood Count:> > HG 9.5, recently 9.2/10.1; WBC 300.7 not significantly higher in the> > last 6 months;> > PLT 144 recently121> > All Electrolytes within range except for Urea 7.9, Normal LDH> > No night sweats, no weight reduction,> > Scan shows lymphs above and below thorax, but no large external lymphs> > (but recently feeling that something is going on inside.....)> > dx Aug 2008> > >> >> Quote Link to comment Share on other sites More sharing options...
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