drug interactions with Topamax

September 22, 2006

Hello Group!

There has been a lot talk about switching from Neurontin to Topamax. My

doctor is trying this with me. I am now down to 900mg of Neurontin a day

(from 3600mg a day) and up to 300mg of Topamax a day. I am also on

Amitriptyline that was just increased to 100mg at night. I found out that

these two medications have an interaction with each other. Does anyone know

of this and have any reaction to it? Since these changes to my medications,

I have been having a lot of problems with my mouth. I have swollen/bruised

gums, canker sores and blisters. My teeth are also very sore to the point

that I am having a lot of pain when I eat. I have asked my doctor (the one

who did the SCS and prescribed the Topamax) about this and he does not feel

the Amitriptyline has anything to do with it. I am confused and frustrated.

Can anyone shed any light on the effects of Topamax, Amitriptyline etc.

Thanks.

September 22, 2006

Hi, Sorry you are having so much trouble with your meds. Unfortunately,

since we all take so much ... we tend to have many problems, reactions,

allergic reactions, side effects, and bad interactions between meds. I Was

on Neorintin, but with 2 weeks, I was so confused, I couldn't figure out how

to get in my car, why I walked into a room, and so on. They thankfully

weaned me off. But, I have been taking Amityrptline for a long long time. It

was given to me about 6 years ago from my neuro-surgeon after they did a

triple discectomy in my cervical spine. I had very bad muscle spasms in my

neck, they had put a titanium plate and 8 screws in there and I just had

allot of problems. Anyway, now, since the last two years of horror, RSD and

implants and so on, my Pain med specialist Dr. that did the implant of my

SCS, they increased the amitryptoline. We all know that it causes

unbelievably sever dry mouth, canker sores and... My primary care DR says

the same thing, even my Podiatrist, who did allot of the surgery to repair

my foot know that.

So talk to your Dr. again. It causes all kinds of mouth problems. There are

toothpastes, mouthwashes, gums and other things that help a little, that are

specifically for this particular problem. Talk to you pharmacist, they can

also help!

Hope you feel better soon,

Amy

September 24, 2006

Hi all, I have a question about teeth. Has anyone had problems with rotting

teeth from all the years of narcs and the other meds that are taken with them? I

guess Im asking because over the last two years my " meth mouth " has gotten so

much worse. Within the last year alone two of my visable teeth have broken off

while chewing on ice(thanks to my super dry mouth) and once while brushing my

teeth. In my case the odds arent my-werent my only problem. Having braces for 5

years then not having the cement taken completely off(never having a single

cavity before then.), and then there is my super fear of the dentist(yes, I know

its silly). I dont know, Im really upset by the whole thing. I wish my first doc

would have told me all of the possible cruddy(is that a word?) things that could

have and would happen, I should have been better at research, maybe asking more

questions would have been beneficial. I could go on with the shouldas/wouldas

all day, but it wont help me now.

Anyway Thanks For Reading This Far. JC:)

[awren@...] wrote: