Re: Lymphadenopthy - Ellen

[Guest guest]

Ellen - Dr. Furman has several trials going on, CAL-101 is only one of them. I cannot speak for him, but his focus appears to be to stay clear of chemos unless necessary, and focus on these other processes that have few side effects and accomplish their goals without cell killing.

In a message dated 8/20/2010 11:41:52 A.M. Eastern Daylight Time, rhudy@... writes:

By "drugs he is using in his trials" do you mean CAL-101? I'm praying for the day it becomes widely available. Ellen jb50192@... wrote: Andy - that's very interesting indeed - different strokes for different folks - I'm glad that this is working for you I met with Dr. Furman today about my possible relapse, and his opinion was to focus on some of the drugs he is using in his trials, which are really not chemos, but which interfere with the signal pathways that enable the leukemic process to grow. There are so many different ways to try to catch this tiger by the tail! RCD is an interesting combo. Who turned you onto it? In a message dated 8/19/2010 6:43:14 P.M. Eastern Daylight Time, unclewolf@... writes:

I can report very good news. I'm receiving RCD (Rituxan/ Cytoxan/ Dexamethasone). It not only got my HGB up from 7.2 to 10.9, but also reduced my WBC from 380,000 to 17,000. Regarding the lymph nodes, I had two large nodes on the sides of my neck and they have almost completely disappeared. I received two treatments so far. The second one was infused almost two weeks ago but my CBC continues to improve. I don't know whether the PR will continue and lead to a CR or whether the improvements will last for a while, but so far I'm I couldn't be happier with the results. I'm 80-year old and unmutated. I was dxd in 12/2005 and asymptomatic until 2 month ago when my AIHA started. Andy Gach

I'm wondering if there has ever been any experimentation of using pheresis for the lymph sytem. I know some patients have used

[Guest guest]

Perhaps the good doctor could weigh in on which one will become available

soonest?

Ellen

jb50192@... wrote:

Ellen

- Dr. Furman has several trials going on, CAL-101 is only one of them.

I cannot speak for him, but his focus appears to be to stay clear of chemos

unless necessary, and focus on these other processes that have few side

effects and accomplish their goals without cell killing. In

a message dated 8/20/2010 11:41:52 A.M. Eastern Daylight Time, rhudy@...

writes:

By

"drugs he is using in his trials" do you mean CAL-101? I'm praying

for the day it becomes widely available.

Ellen

jb50192@...

wrote:

Andy

- that's very interesting indeed - different strokes for different folks

- I'm glad that this is working for you I met with Dr. Furman today about

my possible relapse, and his opinion was to focus on some of the drugs

he is using in his trials, which are really not chemos, but which interfere

with the signal pathways that enable the leukemic process to grow. There

are so many different ways to try to catch this tiger by the tail! RCD

is an interesting combo. Who turned you onto it? In a message dated

8/19/2010 6:43:14 P.M. Eastern Daylight Time, unclewolf@... writes:

I

can report very good news. I'm receiving RCD (Rituxan/ Cytoxan/ Dexamethasone).

It not only got my HGB up from 7.2 to 10.9, but also reduced my WBC from

380,000 to 17,000. Regarding the lymph nodes, I had two large nodes on

the sides of my neck and they have almost completely disappeared. I received

two treatments so far. The second one was infused almost two weeks

ago but my CBC continues to improve. I don't know whether the PR will continue

and lead to a CR or whether the improvements will last for a while, but

so far I'm I couldn't be happier with the results. I'm 80-year old

and unmutated. I was dxd in 12/2005 and asymptomatic until 2 month

ago when my AIHA started. Andy Gach

I'm

wondering if there has ever been any experimentation of using pheresis

for the lymph sytem. I know some patients have used

[Guest guest]

Unfortunately, it is impossible to predict the FDA. These agents are all

available at centers doing clinical trials, but beyond that, it is hard to know.

Rick Furman

> >

> > > Andy - that's very interesting indeed - different strokes

> > > for different folks - I'm glad that this is working for

> > > you I met with Dr. Furman today about my possible relapse,

> > > and his opinion was to focus on some of the drugs he is

> > > using in his trials, which are really not chemos, but

> > > which interfere with the signal pathways that enable the

> > > leukemic process to grow. There are so many different ways

> > > to try to catch this tiger by the tail! RCD is an

> > > interesting combo. Who turned you onto it? In a

> > > message dated 8/19/2010 6:43:14 P.M. Eastern Daylight

> > > Time, unclewolf@... writes:

> > >

> > > I can report very good news. I'm receiving RCD

> > > (Rituxan/ Cytoxan/ Dexamethasone). It not only

> > > got my HGB up from 7.2 to 10.9, but also reduced

> > > my WBC from 380,000 to 17,000. Regarding the

> > > lymph nodes, I had two large nodes on the sides

> > > of my neck and they have almost completely

> > > disappeared. I received two treatments so far.

> > > The second one was infused almost two weeks ago

> > > but my CBC continues to improve. I don't know

> > > whether the PR will continue and lead to a CR or

> > > whether the improvements will last for a while,

> > > but so far I'm I couldn't be happier with the

> > > results. I'm 80-year old and unmutated. I was

> > > dxd in 12/2005 and asymptomatic until 2 month

> > > ago when my AIHA started. Andy Gach

> > >

> > > I'm wondering if there has ever been

> > > any experimentation of using pheresis

> > > for the lymph sytem. I know some

> > > patients have used

> > >

> >

> >

> >

>