Re: Low

[Guest guest]

Hannah--<br><br> Hey there. I don't know if this

the same with everyone else, but I had MORE pain

while taking the anti-innflammatory. I take up to 12

ibuproferin a day, and I can take the edge off most of my

pain. I think that when you take the

anti-innflammatory, it reduces the fluid that is formed in there, and

causes things to rub together more. Personally I think

that God created innflammation for a reason, and it

protects things from any further damag, but that is

clearly a personla thought, but try to stop taking the

anti-innflammatory and see what happens. Good luck and Take care.

Jenna

[Guest guest]

Dr Furman,

 

Thanks so much for responding to my question.

 

I have asked if my low platelets are from the CLL or ITP, his reply was " it's hard to tell " . He is having CBC's done every two weeks to monitor me.

 

Are there specific test that will diagnose this or a series of tests that will point to either CLL or ITP?

 

Thanks,

Dave Tipton

On Fri, May 7, 2010 at 9:09 PM, R. Furman <rrfurman@...> wrote:

 

The most important thing is to confirm that this is ITP and not one of the many other reasons CLL patients can develop thrombocytopenia.  If it is ITP, one thing that I have found helpful is using a high dose of rituximab.  I might give 500 mg/m2 x 4-8 cycles.  You have to remember that there are many " decoy " targets present.  The residual normal B cells are likely the ones making the antibodies in ITP and all of the CLL cells soak up the rituximab.

Rick Furman, MD

[Guest guest]

A bone marrow biopsy would be the most definitive means for knowing. There are

other means that suggest, such as response to different treatment.

>

> >

> >

> > The most important thing is to confirm that this is ITP and not one of the

> > many other reasons CLL patients can develop thrombocytopenia. If it is ITP,

> > one thing that I have found helpful is using a high dose of rituximab. I

> > might give 500 mg/m2 x 4-8 cycles. You have to remember that there are many

> > " decoy " targets present. The residual normal B cells are likely the ones

> > making the antibodies in ITP and all of the CLL cells soak up the rituximab.

> >

> > Rick Furman, MD

> >

> >

> >

>

[Guest guest]

Can someone define ITP?On Sat, May 8, 2010 at 11:55 AM, Tipton <dcdtip@...> wrote:

 

Dr Furman,

 

Thanks so much for responding to my question.

 

I have asked if my low platelets are from the CLL or ITP, his reply was " it's hard to tell " . He is having CBC's done every two weeks to monitor me.

 

Are there specific test that will diagnose this or a series of tests that will point to either CLL or ITP?

 

Thanks,

Dave Tipton

On Fri, May 7, 2010 at 9:09 PM, R. Furman <rrfurman@...> wrote:

 

The most important thing is to confirm that this is ITP and not one of the many other reasons CLL patients can develop thrombocytopenia.  If it is ITP, one thing that I have found helpful is using a high dose of rituximab.  I might give 500 mg/m2 x 4-8 cycles.  You have to remember that there are many " decoy " targets present.  The residual normal B cells are likely the ones making the antibodies in ITP and all of the CLL cells soak up the rituximab.

Rick Furman, MD

[Guest guest]

Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low

platelet count (thrombocytopenia)

A normal platelet count is considered to be in the range of 150,000–450,000 per

cubic millimeter (mm3) of blood for most healthy individuals. Hence one may be

considered thrombocytopenic below that range, although the threshold for a

diagnosis of ITP is not tied to any specific number.

~chirs

[Guest guest]

Thanks for the response..  Greatly appreciatedOn Sun, May 9, 2010 at 12:11 PM, cllcanada <cllcanada@...> wrote:

 

Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia)

A normal platelet count is considered to be in the range of 150,000–450,000 per cubic millimeter (mm3) of blood for most healthy individuals. Hence one may be considered thrombocytopenic below that range, although the threshold for a diagnosis of ITP is not tied to any specific number.

~chirs

[Guest guest]

One thing to add is that ITP is when the platelets are being destroyed by

antibodies directed at the platelets. It is very similar to autoimmune

hemolytic anemias. Both are forms of autoimmune disease, one against red blood

cells (AIHA) and one against platelets.

Rick Furman, MD

>

>

> Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low

platelet count (thrombocytopenia)

>

>

> A normal platelet count is considered to be in the range of 150,000–450,000

per cubic millimeter (mm3) of blood for most healthy individuals. Hence one may

be considered thrombocytopenic below that range, although the threshold for a

diagnosis of ITP is not tied to any specific number.

>

>

>

> ~chirs

>