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Re: 800mg of Gleevec/

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Hi , the reason why im off Gleevec is cause i had such severe

side effects with toxicity that I just had to give my body a

rest..no ive not had any other treatment and yes you do have to take

it till we die or transplant (thats what they tell us anyway). The

other thing i was interested in is that you mentioned

remission....Tim told me that its not remission if you have to take

a drug to stay alive. Gleevec keeps it at bay but not remission.

Some would disagree with that but im only repeating what my Onc. Tim

tells me as ive mentioned to him that ive heard the

term 'remission' alot on here.

Susie Leech

DX Nov 2002

>

>

> In a message dated 1/30/2006 5:19:59 P.M. Central Standard Time,

> leechys@b... writes:

>

> ..its only now im toxic free..and

> thats cause I am off Gleevec and have been for two months.

>

>

> Suzie, how is it that you are off Gleevec? My doctor told me I

would take

> it until my dying day.

>

> I've never been on the high dose - started with 400 mgs daily and

have

> stayed there for two and a half years. I've been in remission for

most of the

> time, but the prospect of not taking it at all is very

interesting. Did you

> have some other treatment too? I'm too old for transplants.

>

> I do have the upset tummy and diahrrea sometimes. Depends on what

I take it

> with. If I take it with Ensure or a yogurt drink I don't get

sick. If I

> only take it with water it will do me in very quickly.

>

> I just joined the list and will enjoy hearing about all of your

experiences.

> in MN

>

>

>

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At 12:33 PM 1/31/06 +0000, you wrote:

> The

>other thing i was interested in is that you mentioned

>remission....Tim told me that its not remission if you have to take

>a drug to stay alive. Gleevec keeps it at bay but not remission.

>Some would disagree with that but im only repeating what my Onc. Tim

> tells me as ive mentioned to him that ive heard the

>term 'remission' alot on here.

Hi and Susie,

We don't really go into remission as they speak of it with other

cancers......our disease is really managed or controlled by Gleevec,

but we do remain drug dependent. Our goal is to have the fewest

possible leukemia cells.....or minimal residual disease.

It is more accurate to think of CCR as complete cytogenetic " response "

(which is how Dr. Druker thinks of it) than remission. We are talking

about the level of response that we have had to the drug.

This goes even for PCRU.....this does not mean that you don't have

any cml cells in your body (just undetectable by the level of testing

we have available)..........which is why if you go off drug, you relapse

(and get more ph+ cells).

C.

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In a message dated 1/31/2006 6:40:01 A.M. Central Standard Time,

leechys@... writes:

Gleevec keeps it at bay but not remission.

Some would disagree with that but im only repeating what my Onc. Tim

tells me as ive mentioned to him that ive heard the

term 'remission' alot on here.

Hi Susie,

I guess that makes sense, but my oncologist refers to what I'm in as

remission, so I do too. Sorry if that upsets some people. Sometimes I feel

very curious to see what would happen if I quit taking it for awhile. Too

chicken to do that though and I wouldn't want to make my oncologist angry at

me.

I'm just thankful that Gleevec was developed as I have lots of yarn to knit

and fiber to spin before I'm through here on earth. To say nothing of the

books to read and my family to love.

in MN

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