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Tumor Lysis with FR tx

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I'm heading into treatment soon with Fludarabine & Rituxan. My WBC is around 300,000 and I'm concerned about tumor lysis. My oncologist was originally going to leave Rituxan out of the 1st round, but now he says that his research convinced him that Rituxan will be safe. He is planning to give me allopurinol.

Can anyone point me to an article that addresses this issue?

Ron

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