Re: basophils/Amy/A related question

[Guest guest]

Hi ,

From what I understand (and remember from biology class), the

term " interphase cells " refers to a particular part of the cell

cycle.....in other words it describes a part of the life of a cell

as it divides through the various stages....Gap 0, Gap 1, Synthesis

and Gap 2 are all part of the interphase cycle. Whereas a basophil

is a particular type of cell.

You would know what percentage of basophils you had from a simple

CBC but you would need to have a FISH to see how many cells are in

the interphase cycle...I'm not sure what percentage are supposed to

be in the interphase cycle so I can't tell you if 3% is high or low

or normal...sorry.

Tracey

> > > Hey everyone! I'm home. I had my appointment with Dr.

> Kantarjian

> > > yesterday and my BMA. Not the best experience to date. Two

dry

> > bma

> > > draws, didn't start my visit off right. Third one worked,

now

> w/o

> > my

> > > shedding some tears <I just hate that> Saw Dr. K and he was

> > concerned

> > > because my Basophils are now at 2% from 0, which he

said 'COULD'

> > mean

> > > my phillies are coming back or are up. I should have the

BMA

> > results

> > > in two weeks and we will decide at that time which course to

> > take. He

> > > gave me a couple of options........1. We could raise my dose

on

> > > Gleevec, as I only take 400mg, and have for the last two

years.

> He

> > is

> > > concerned about the increased side effects, since I have a

> > difficult

> > > time now. 2. I could go on the Phase II trail of BMS 3.

AMN107

> > > Trial. Now with either of the last two options I have to be

in

> > Houston

> > > for a minimum of 1 month, and then be there once monthly

there

> > after.

> > > I can do that. Anyway thats my news and my choices. I

don't

> know

> > much

> > > about the AMN107, except that it is by Novartis. Anyone

have

> more

> > > details? Thanks for listening!

> > >

> > > Amy B.

>

>

>

>

>

> -------------------------------------------------------------------

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>

[Guest guest]

Interphase cells are on a much more cytogenic level than Basophils,

from what I read. I asked Dr. K about the increase in Gleevec and he

said he would rather go to one one trial medications. Due to the side

effects. Basophils are one of the components of the WBC, and show up in

a CBC/Differential.

http://www.funpecrp.com.br/gmr/year2002/vol2-1/gmr0013_full_text.htm

This is where I read about interphase cells.