Guest guest Posted May 30, 2005 Report Share Posted May 30, 2005 -Hi Margot, congratulations on your continued great test results. I hope I can do as well as you are. Shari from Kansas -- In , " Margot M " <redbudln@c...> wrote: > Hi: > Just thought I'd report that I just got my latest PCR results back > from MDACC. When I found out that the results just were for a qRT > PCR with a sensitivity of 100,000 cells, I was taken aback because > they had always done nested if the quantitative PCR was negative. > So I quickly e-mailed Dr. Koller to ask if nested had been done and > asked if possibly the nested wasn't completed yet. Here is the > answer I got back: > > " The lab has found that with improvements in realtime PCR that the > nested PCR will not add sensitivity unless there is a problem with > amplifying abl, which in your case there was not. Also, there was > no discrepancy with the genescan. They will stick by their results > with a sensitivity of 1:100000. > Your reward for such an excellent test: stay on your Gleevec. " > > Of course, I am very happy with these results--who wouldn't be. > But I still I could use some explanation of exactly what " amplification " > means in this case as I always thought that the amplification > happens with the nested PCR, also what " genescan " stands for. > Anyone up to this explanation? > > Margot > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 31, 2005 Report Share Posted May 31, 2005 Margot, I got the same results on my last QPCR. Do you know if this mean we are at molecular remission or PCRU? My next appt at Moffit Center will be July 13 . I will ask my Doctor what does it mean. T dxd 1/3 CCR 7/03 -- In , " Margot M " <redbudln@c...> wrote: > Hi: > Just thought I'd report that I just got my latest PCR results back > from MDACC. When I found out that the results just were for a qRT > PCR with a sensitivity of 100,000 cells, I was taken aback because > they had always done nested if the quantitative PCR was negative. > So I quickly e-mailed Dr. Koller to ask if nested had been done and > asked if possibly the nested wasn't completed yet. Here is the > answer I got back: > > " The lab has found that with improvements in realtime PCR that the > nested PCR will not add sensitivity unless there is a problem with > amplifying abl, which in your case there was not. Also, there was > no discrepancy with the genescan. They will stick by their results > with a sensitivity of 1:100000. > Your reward for such an excellent test: stay on your Gleevec. " > > Of course, I am very happy with these results--who wouldn't be. > But I still I could use some explanation of exactly what " amplification " > means in this case as I always thought that the amplification > happens with the nested PCR, also what " genescan " stands for. > Anyone up to this explanation? > > Margot > > > > Quote Link to comment Share on other sites More sharing options...
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