Guest guest Posted November 5, 2004 Report Share Posted November 5, 2004 Has anyone had treatment with low dose methotrexate for asthma? I cannot take prednisone as my body doesn't react properly to it. In the past I had a syncope and was on more than the maximum oral dosage, then hospitalized for 1 week on IV steroids. The tapering was a nightmare. My current allergist/immunologist who diagnosed my Samters agreed that I should not use steroids. Last Fall he put me on methotrexate for 6 months and I did much better, asthma-wise. He told me that there is research going on in England which points to this as a good treatment for my kind of asthma. I currently have a stubborn sinus infection (am on my 3rd round of antibiotics) so I can't go back on it until the infection subsides because it suppresses the immune system and I'd never get rid of the infection. The side effects of the methotrexate were tolerable. Unfortunately I could not give blood while on it, but I did that a few weeks ago so at least I did what I could. I am fortunate in that I generally have my sense of smell and the asthma only gets really bad (like it is now) with infections, some weather conditions and major stress. Mornings have been scary around here the last few days with peak flows about 2/3 or less than they should be. He changed my meds some and this morning was better -- still well-depressed but more tolerable. I live on an island, which makes treatment even more hairy in an emergency. Anyway, has anyone tried methotrexate for the asthma? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 5, 2004 Report Share Posted November 5, 2004 I assume you are on an inhaled asthma controller like ADvair. You can also use atrovent inhaler as well and should have a nebulizer for resue or emergencies. The doc could still give you IM injections of steroid of things got really bad. Carol A nonsteroid treatment > > > Has anyone had treatment with low dose methotrexate for asthma? I > cannot take prednisone as my body doesn't react properly to it. In > the past I had a syncope and was on more than the maximum oral > dosage, then hospitalized for 1 week on IV steroids. The tapering > was a nightmare. My current allergist/immunologist who diagnosed my > Samters agreed that I should not use steroids. Last Fall he put me > on methotrexate for 6 months and I did much better, asthma-wise. He > told me that there is research going on in England which points to > this as a good treatment for my kind of asthma. I currently have a > stubborn sinus infection (am on my 3rd round of antibiotics) so I > can't go back on it until the infection subsides because it > suppresses the immune system and I'd never get rid of the infection. > The side effects of the methotrexate were tolerable. Unfortunately I > could not give blood while on it, but I did that a few weeks ago so > at least I did what I could. I am fortunate in that I generally have > my sense of smell and the asthma only gets really bad (like it is > now) with infections, some weather conditions and major stress. > Mornings have been scary around here the last few days with peak > flows about 2/3 or less than they should be. He changed my meds some > and this morning was better -- still well-depressed but more > tolerable. I live on an island, which makes treatment even more > hairy in an emergency. Anyway, has anyone tried methotrexate for the > asthma? > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 5, 2004 Report Share Posted November 5, 2004 Yes I am on Advair, Singulair, DuoNeb during a flare (like now) or MaxAir when I am not in Status Asthmaticus. I am thinking of going back on the methotrexate once this infection subsides. It seemed to hold me in good stead while I was on it. I was wondering if anyone else has done methotrexate and how they felt on it. I don't want to go near systemic steroids again. My body just does not react properly with them. Thank you for your response. I agree with having the nebulizer on hand. Before I had one I was on the ambulance too many times. Since, I've not been hospitalized with my asthma at all. > I assume you are on an inhaled asthma controller like ADvair. You can also > use atrovent inhaler as well and should have a nebulizer for resue or > emergencies. The doc could still give you IM injections of steroid of things > got really bad. Carol > A nonsteroid treatment > > > > > > > > Has anyone had treatment with low dose methotrexate for asthma? I > > cannot take prednisone as my body doesn't react properly to it. In > > the past I had a syncope and was on more than the maximum oral > > dosage, then hospitalized for 1 week on IV steroids. The tapering > > was a nightmare. My current allergist/immunologist who diagnosed my > > Samters agreed that I should not use steroids. Last Fall he put me > > on methotrexate for 6 months and I did much better, asthma-wise. He > > told me that there is research going on in England which points to > > this as a good treatment for my kind of asthma. I currently have a > > stubborn sinus infection (am on my 3rd round of antibiotics) so I > > can't go back on it until the infection subsides because it > > suppresses the immune system and I'd never get rid of the infection. > > The side effects of the methotrexate were tolerable. Unfortunately I > > could not give blood while on it, but I did that a few weeks ago so > > at least I did what I could. I am fortunate in that I generally have > > my sense of smell and the asthma only gets really bad (like it is > > now) with infections, some weather conditions and major stress. > > Mornings have been scary around here the last few days with peak > > flows about 2/3 or less than they should be. He changed my meds some > > and this morning was better -- still well-depressed but more > > tolerable. I live on an island, which makes treatment even more > > hairy in an emergency. Anyway, has anyone tried methotrexate for the > > asthma? > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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