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I am looking this up.

If any one knows what this means please let me know.

Test results.

Epstein-barr virus VCA (IGG AB) = 7.00

EBV Nuclear Antigen (EBNA) AB (IGG) = 5.00

Normal range < or = 0.90

Equivocal 0.91 - 1.09

Positive > or = 1.10

The last 5 doctors have no doubt that I have a problem with my

immune-system. But if the insurance company, wants to drag there feet I am

looking for un-equivocal proof.

(I can already show after I breath fumes my venous blood gas test is

critical.) (po2 = 40, should be round 25)

Ron

I received my paperwork on Lyme

The western blot IGM was positive for 3 bands 39 and 41, 23-25. I only

needed 2 to be positive for lyme. I rife at least once per week. I wonder if

these would have been higher if I didn't rife. I will be rifing more often

and with the lyme frequencies. Quest lab said my vit. D level on

1,25-dihydroxy was 70 10 points higher than normal. What does this mean to

you? What would you do? I am being sent to the hmos infectious disease Dr.

and I want to be knowledgeable. I assume igm is current and not past

infection. joyce jamkaye@...

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hi ron i think it refers to different components of the epstein barr

virus... like the outer portion and the innner portion of it.

you are definately out of normal range by alot...i bet if they take the

simple epstein barr virus titers u will be very high...my labs seem

similiar to yours and i had ebv in the 1000s years ago. tealk

> [Original Message]

> From: Ron <salesman11@...>

> < >

> Date: 10/2/2004 10:04:59 AM

> Subject: RE: Epstein-barr virus

>

>

> I am looking this up.

> If any one knows what this means please let me know.

>

> Test results.

>

> Epstein-barr virus VCA (IGG AB) = 7.00

>

> EBV Nuclear Antigen (EBNA) AB (IGG) = 5.00

>

> Normal range < or = 0.90

> Equivocal 0.91 - 1.09

> Positive > or = 1.10

>

>

> The last 5 doctors have no doubt that I have a problem with my

> immune-system. But if the insurance company, wants to drag there feet I am

> looking for un-equivocal proof.

>

> (I can already show after I breath fumes my venous blood gas test is

> critical.) (po2 = 40, should be round 25)

> Ron

>

> I received my paperwork on Lyme

>

>

> The western blot IGM was positive for 3 bands 39 and 41, 23-25. I only

> needed 2 to be positive for lyme. I rife at least once per week. I wonder

if

> these would have been higher if I didn't rife. I will be rifing more often

> and with the lyme frequencies. Quest lab said my vit. D level on

> 1,25-dihydroxy was 70 10 points higher than normal. What does this mean to

> you? What would you do? I am being sent to the hmos infectious disease Dr.

> and I want to be knowledgeable. I assume igm is current and not past

> infection. joyce jamkaye@...

>

>

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  • 4 years later...

Has anyone here had an episode of infectious mononucleosis (Epstein-Barr virus) ?-------------J Med Virol. 2009 Sep;81(9):1613-9. Links

Prevalence of human papilloma virus and human herpes virus types 1-7 in human nasal polyposis.

Zaravinos A, Bizakis J, Spandidos DA.

Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece.

This

study aimed to investigate the prevalence of human papilloma virus

(HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus

(VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human

herpes virus-6/-7 (HHV-6/-7) in 23 human nasal polyps by applying PCR.

Two types of control tissues were used: adjacent inferior/middle

turbinates from the patients and inferior/middle turbinates from 13

patients undergoing nasal corrective surgery. EBV was the virus most

frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and CMV

(4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV

was also detected in the adjacent turbinates (4%) and the adjacent

middle turbinate (4%) of one of the HPV-positive patients. EBV, HSV,

and CMV were not detected in the adjacent turbinates of the EBV-, HSV-

or CMV-positive patients. All mucosae were negative for the VZV, HHV-6,

and HHV-7. This is the first study to deal with the involvement of a

comparable group of viruses in human nasal polyposis. The findings

support the theory that the presence of viral EBV markedly influences

the pathogenesis of these benign nasal tumors. The low incidence of HPV

detected confirms the hypothesis that HPV is correlated with infectious

mucosal lesions to a lesser extent than it is with proliferative

lesions, such as inverted papilloma. The low incidence of HSV-1 and CMV

confirms that these two herpes viruses may play a minor role in the

development of nasal polyposis. Double infection with HSV-1 and CMV may

also play a minor, though causative, role in nasal polyp development.

VZV and HHV-6/-7 do not appear to be involved in the pathogenesis of

these mucosal lesions.

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Wow, Jane, this is really weird. I had no sinus problems, went in for surgery to correct a deviated septum, and then all my troubles began. After surgery when I was very ill I too was tested and found to have both EBV and Lymes disease! I think I'm over the EBV -- but haven't been retested since I tested positive twice -- I've also tested positive twice for active Lymes. I had some antibiotics for my newly developed sinus condition -- so am hoping they have taken care of the Lymes. I wonder what the connection is? Didn't have Samter's before all this either. The Lymes is strange because I live in Colorado, where cases of Lymes are very rare. Just had extensive surgery Thursday -- my nose is in a cast and I've still got a lot of pain, but I hope it did the trick. I see the doctor tomorrow. JoanOn Sep 22, 2009, at 5:24 AM, Jane Marino wrote: I was diagnosed with Epstein Barr at the same time I was diagnosed with Lymes Disease about 5 years ago.. However, I went through extensive treatment to rid myself of the Lymes disease and am now Lyme-free. But I was very sick when originally diagnosed with both. Jane From: asfy <asfyso (DOT) fr>Subject: Epstein-Barr virussamters Date: Tuesday, September 22, 2009, 2:15 AM Has anyone here had an episode of infectious mononucleosis (Epstein-Barr virus) ?------------ - J Med Virol. 2009 Sep;81(9):1613- 9. Links Prevalence of human papilloma virus and human herpes virus types 1-7 in human nasal polyposis. Zaravinos A, Bizakis J, Spandidos DA. Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece. This study aimed to investigate the prevalence of human papilloma virus (HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6/-7 (HHV-6/-7) in 23 human nasal polyps by applying PCR. Two types of control tissues were used: adjacent inferior/middle turbinates from the patients and inferior/middle turbinates from 13 patients undergoing nasal corrective surgery. EBV was the virus most frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and CMV (4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV was also detected in the adjacent turbinates (4%) and the adjacent middle turbinate (4%) of one of the HPV-positive patients. EBV, HSV, and CMV were not detected in the adjacent turbinates of the EBV-, HSV- or CMV-positive patients. All mucosae were negative for the VZV, HHV-6, and HHV-7. This is the first study to deal with the involvement of a comparable group of viruses in human nasal polyposis. The findings support the theory that the presence of viral EBV markedly influences the pathogenesis of these benign nasal tumors. The low incidence of HPV detected confirms the hypothesis that HPV is correlated with infectious mucosal lesions to a lesser extent than it is with proliferative lesions, such as inverted papilloma. The low incidence of HSV-1 and CMV confirms that these two herpes viruses may play a minor role in the development of nasal polyposis. Double infection with HSV-1 and CMV may also play a minor, though causative, role in nasal polyp development.. VZV and HHV-6/-7 do not appear to be involved in the pathogenesis of these mucosal lesions.

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I had a pretty bad case of mono was I was a teenager but my

asthma, aspirin allergy, polyps and nasal issues didn’t really develop until

much later, more like my early 30s. I’d be skeptical of a relationship in me

considering I think a lot of my issues are genetic in that my dad has the same

allergies as me and he also has polyps, though he does not have Samter’s since

he does not have asthma nor is he allergic to aspirin. It is an interesting

thing to consider though! I also never realized mono and Epstein-Barr were the

same thing.

K.

From:

samters [mailto:samters ] On Behalf Of asfy

Sent: Tuesday, September 22, 2009 4:15 AM

samters

Subject: Epstein-Barr virus

Has anyone here had an episode of infectious

mononucleosis (Epstein-Barr virus) ?

-------------

J Med Virol. 2009 Sep;81(9):1613-9. Links

Prevalence of human papilloma virus and human

herpes virus types 1-7 in human nasal polyposis.

Zaravinos

A, Bizakis

J, Spandidos

DA.

Laboratory of Virology, Medical

School, University of Crete, Heraklion, Crete, Greece.

This study aimed to investigate the

prevalence of human papilloma virus (HPV), herpes simplex virus-1/-2

(HSV-1/-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV),

cytomegalovirus (CMV), and human herpes virus-6/-7 (HHV-6/-7) in 23 human nasal

polyps by applying PCR. Two types of control tissues were used: adjacent

inferior/middle turbinates from the patients and inferior/middle turbinates

from 13 patients undergoing nasal corrective surgery. EBV was the virus

most frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and

CMV (4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV was

also detected in the adjacent turbinates (4%) and the adjacent middle turbinate

(4%) of one of the HPV-positive patients. EBV, HSV, and CMV were not detected

in the adjacent turbinates of the EBV-, HSV- or CMV-positive patients. All

mucosae were negative for the VZV, HHV-6, and HHV-7. This is the first study to

deal with the involvement of a comparable group of viruses in human nasal

polyposis. The findings support the theory that the presence of viral EBV

markedly influences the pathogenesis of these benign nasal tumors. The

low incidence of HPV detected confirms the hypothesis that HPV is correlated

with infectious mucosal lesions to a lesser extent than it is with

proliferative lesions, such as inverted papilloma. The low incidence of HSV-1

and CMV confirms that these two herpes viruses may play a minor role in the

development of nasal polyposis. Double infection with HSV-1 and CMV may also

play a minor, though causative, role in nasal polyp development. VZV and

HHV-6/-7 do not appear to be involved in the pathogenesis of these mucosal

lesions.

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To be precise, the abstract theorizes a promoting role of Epstein-Barr

virus in nasal polyposis, but it does not say what kind of role, and it

must also be kept in mind that EBV is a very ubiquitous virus, meaning

that almost all of the adult population is a carrier, even though they

have not have had acute episodes.

http://en.wikipedia.org/wiki/Epstein-Barr_virus

So, all this does not necessarily mean that EBV is a trigger of polyps -

though it could help ; however, it obviously finds itself comfortable in

polyp tissues, and that is an interesting observation.

>

> I had a pretty bad case of mono was I was a teenager but my asthma,

aspirin

> allergy, polyps and nasal issues didn't really develop until much

later,

> more like my early 30s. I'd be skeptical of a relationship in me

> considering I think a lot of my issues are genetic in that my dad has

the

> same allergies as me and he also has polyps, though he does not have

> Samter's since he does not have asthma nor is he allergic to aspirin.

It is

> an interesting thing to consider though! I also never realized mono

and

> Epstein-Barr were the same thing.

>

>

>

> K.

>

>

>

> From: samters [mailto:samters ] On

Behalf Of

> asfy

> Sent: Tuesday, September 22, 2009 4:15 AM

> samters

> Subject: Epstein-Barr virus

>

>

>

>

>

> Has anyone here had an episode of infectious mononucleosis

(Epstein-Barr

> virus) ?

>

> -------------

>

> J Med Virol. 2009 Sep;81(9):1613-9.

>

<http://www.ncbi.nlm.nih.gov/entrez/utils/fref.fcgi?PrId=3058 & itool=Abst\

ract

>

Plus-def & uid=19626617 & nlmid=7705876 & db=pubmed & url=http://dx.doi.org/10.1\

002/

> jmv.21534> Click here to read Links

>

>

> Prevalence of human papilloma virus and human herpes virus types 1-7

in

> human nasal polyposis.

>

>

>

>

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%22Z\

arav

>

inos%20A%22%5BAuthor%5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_Result\

sPan

> el.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus> Zaravinos A,

>

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%22B\

izak

>

is%20J%22%5BAuthor%5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP\

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> .Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus> Bizakis J,

>

<http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=Search & Term=%22S\

pand

>

idos%20DA%22%5BAuthor%5D & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_Resul\

tsPa

> nel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus> Spandidos DA.

>

> Laboratory of Virology, Medical School, University of Crete,

Heraklion,

> Crete, Greece.

>

> This study aimed to investigate the prevalence of human papilloma

virus

> (HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus

(VZV),

> Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes

virus-6/-7

> (HHV-6/-7) in 23 human nasal polyps by applying PCR. Two types of

control

> tissues were used: adjacent inferior/middle turbinates from the

patients and

> inferior/middle turbinates from 13 patients undergoing nasal

corrective

> surgery. EBV was the virus most frequently detected (35%), followed by

HPV

> (13%), HSV-1 (9%), and CMV (4%). The CMV-positive polyp was

simultaneously

> positive for HSV-1. HPV was also detected in the adjacent turbinates

(4%)

> and the adjacent middle turbinate (4%) of one of the HPV-positive

patients.

> EBV, HSV, and CMV were not detected in the adjacent turbinates of the

EBV-,

> HSV- or CMV-positive patients. All mucosae were negative for the VZV,

HHV-6,

> and HHV-7. This is the first study to deal with the involvement of a

> comparable group of viruses in human nasal polyposis. The findings

support

> the theory that the presence of viral EBV markedly influences the

> pathogenesis of these benign nasal tumors. The low incidence of HPV

detected

> confirms the hypothesis that HPV is correlated with infectious mucosal

> lesions to a lesser extent than it is with proliferative lesions, such

as

> inverted papilloma. The low incidence of HSV-1 and CMV confirms that

these

> two herpes viruses may play a minor role in the development of nasal

> polyposis. Double infection with HSV-1 and CMV may also play a minor,

though

> causative, role in nasal polyp development. VZV and HHV-6/-7 do not

appear

> to be involved in the pathogenesis of these mucosal lesions.

>

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Joan, I live in Colorado too!!! Doctors didn't believe my positive results for Lyme were correct at first. They diagnosed me with Chronic Fatigue Syndrome and sent me on my way. I ended up leaving my job for a year and a half because I couldn't function.. I spent the better part of 2 years flying back and forth to an Integrative medical clinic in Nevada where they treated me for the EBV and Lymes Disease. During the process I also became addicted to pain killers, so when all of my treatment was done, I had to go through withdrawal. I am happy to say today that I am certain I am Lyme and EBV "free"! But it took some work!

Jane

From: asfy <asfyso (DOT) fr>Subject: Epstein-Barr virussamters@groups .comDate: Tuesday, September 22, 2009, 2:15 AM

Has anyone here had an episode of infectious mononucleosis (Epstein-Barr virus) ?------------ -

J Med Virol. 2009 Sep;81(9):1613- 9. Links

Prevalence of human papilloma virus and human herpes virus types 1-7 in human nasal polyposis.

Zaravinos A, Bizakis J, Spandidos DA.

Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece.

This study aimed to investigate the prevalence of human papilloma virus (HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6/-7 (HHV-6/-7) in 23 human nasal polyps by applying PCR. Two types of control tissues were used: adjacent inferior/middle turbinates from the patients and inferior/middle turbinates from 13 patients undergoing nasal corrective surgery. EBV was the virus most frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and CMV (4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV was also detected in the adjacent turbinates (4%) and the adjacent middle turbinate (4%) of one of the HPV-positive patients. EBV, HSV, and CMV were not detected in the adjacent turbinates of the EBV-, HSV- or CMV-positive patients. All mucosae were negative for the VZV, HHV-6, and HHV-7. This is the first study

to deal with the involvement of a comparable group of viruses in human nasal polyposis. The findings support the theory that the presence of viral EBV markedly influences the pathogenesis of these benign nasal tumors. The low incidence of HPV detected confirms the hypothesis that HPV is correlated with infectious mucosal lesions to a lesser extent than it is with proliferative lesions, such as inverted papilloma. The low incidence of HSV-1 and CMV confirms that these two herpes viruses may play a minor role in the development of nasal polyposis. Double infection with HSV-1 and CMV may also play a minor, though causative, role in nasal polyp development.. . VZV and HHV-6/-7 do not appear to be involved in the pathogenesis of these mucosal lesions.

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Jane, that is so interesting! I first maybe thought I had chronic fatigue or something as well, but had some weird hunch about Lymes and went to a nurse who also tested me for mono. I've tested positive twice with two different labs for Lymes, because even I doubted the first test. I'm going to wait and see how I'm doing after my newly remodeled nose emerges from its wraps and my desens in early October -- but I may want to get more information from you about the place in Nevada later. My sister knows of a Lyme expert in Stanford, who is booked up months in advance, but right now I'm hoping I don' t have to go that far. The antibiotics I've had so far did nothing for my nose, but do seem to have helped somewhat with the Lyme symptoms.I'm very glad I joined this group -- otherwise I'd never know that someone else from CO had the same series of odd conditions together.JoanOn Sep 22, 2009, at 5:48 PM, Jane Marino wrote: Joan, I live in Colorado too!!! Doctors didn't believe my positive results for Lyme were correct at first. They diagnosed me with Chronic Fatigue Syndrome and sent me on my way. I ended up leaving my job for a year and a half because I couldn't function.. I spent the better part of 2 years flying back and forth to an Integrative medical clinic in Nevada where they treated me for the EBV and Lymes Disease. During the process I also became addicted to pain killers, so when all of my treatment was done, I had to go through withdrawal. I am happy to say today that I am certain I am Lyme and EBV "free"! But it took some work! Jane From: asfy <asfyso (DOT) fr>Subject: Epstein-Barr virussamters@groups .comDate: Tuesday, September 22, 2009, 2:15 AM Has anyone here had an episode of infectious mononucleosis (Epstein-Barr virus) ?------------ - J Med Virol. 2009 Sep;81(9):1613- 9. Links Prevalence of human papilloma virus and human herpes virus types 1-7 in human nasal polyposis. Zaravinos A, Bizakis J, Spandidos DA. Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece. This study aimed to investigate the prevalence of human papilloma virus (HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6/-7 (HHV-6/-7) in 23 human nasal polyps by applying PCR. Two types of control tissues were used: adjacent inferior/middle turbinates from the patients and inferior/middle turbinates from 13 patients undergoing nasal corrective surgery. EBV was the virus most frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and CMV (4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV was also detected in the adjacent turbinates (4%) and the adjacent middle turbinate (4%) of one of the HPV-positive patients. EBV, HSV, and CMV were not detected in the adjacent turbinates of the EBV-, HSV- or CMV-positive patients. All mucosae were negative for the VZV, HHV-6, and HHV-7. This is the first study to deal with the involvement of a comparable group of viruses in human nasal polyposis. The findings support the theory that the presence of viral EBV markedly influences the pathogenesis of these benign nasal tumors. The low incidence of HPV detected confirms the hypothesis that HPV is correlated with infectious mucosal lesions to a lesser extent than it is with proliferative lesions, such as inverted papilloma. The low incidence of HSV-1 and CMV confirms that these two herpes viruses may play a minor role in the development of nasal polyposis. Double infection with HSV-1 and CMV may also play a minor, though causative, role in nasal polyp development.. . VZV and HHV-6/-7 do not appear to be involved in the pathogenesis of these mucosal lesions.

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Joan, Where did were you tested for Lymes? Do you remember what type of testing you had?

From: asfy <asfyso (DOT) fr>Subject: Epstein-Barr virussamters@groups .comDate: Tuesday, September 22, 2009, 2:15 AM

Has anyone here had an episode of infectious mononucleosis (Epstein-Barr virus) ?------------ -

J Med Virol. 2009 Sep;81(9):1613- 9. Links

Prevalence of human papilloma virus and human herpes virus types 1-7 in human nasal polyposis.

Zaravinos A, Bizakis J, Spandidos DA.

Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece.

This study aimed to investigate the prevalence of human papilloma virus (HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6/-7 (HHV-6/-7) in 23 human nasal polyps by applying PCR. Two types of control tissues were used: adjacent inferior/middle turbinates from the patients and inferior/middle turbinates from 13 patients undergoing nasal corrective surgery. EBV was the virus most frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and CMV (4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV was also detected in the adjacent turbinates (4%) and the adjacent middle turbinate (4%) of one of the HPV-positive patients. EBV, HSV, and CMV were not detected in the adjacent turbinates of the EBV-, HSV- or CMV-positive patients. All mucosae were negative for the VZV, HHV-6, and HHV-7. This is the first study

to deal with the involvement of a comparable group of viruses in human nasal polyposis. The findings support the theory that the presence of viral EBV markedly influences the pathogenesis of these benign nasal tumors. The low incidence of HPV detected confirms the hypothesis that HPV is correlated with infectious mucosal lesions to a lesser extent than it is with proliferative lesions, such as inverted papilloma. The low incidence of HSV-1 and CMV confirms that these two herpes viruses may play a minor role in the development of nasal polyposis. Double infection with HSV-1 and CMV may also play a minor, though causative, role in nasal polyp development. . . VZV and HHV-6/-7 do not appear to be involved in the pathogenesis of these mucosal

lesions.

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Jane,I was tested by IGENEX which is supposed to be a Lyme specialist lab. I had a bunch of panels -- and tested negative on B Burgdorferi, but positive on IgM Western Blot -= with enough positive markers to rule out false positive caused by EBV. I'm not seeing anyone versed in treating Lymes -- the lab said that the results meant the disease was active, but could be reactivation of old disease.On Sep 22, 2009, at 7:23 PM, Jane Marino wrote: Joan, Where did were you tested for Lymes? Do you remember what type of testing you had? From: asfy <asfyso (DOT) fr>Subject: Epstein-Barr virussamters@groups .comDate: Tuesday, September 22, 2009, 2:15 AM Has anyone here had an episode of infectious mononucleosis (Epstein-Barr virus) ?------------ - J Med Virol. 2009 Sep;81(9):1613- 9. Links Prevalence of human papilloma virus and human herpes virus types 1-7 in human nasal polyposis. Zaravinos A, Bizakis J, Spandidos DA. Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece. This study aimed to investigate the prevalence of human papilloma virus (HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6/-7 (HHV-6/-7) in 23 human nasal polyps by applying PCR. Two types of control tissues were used: adjacent inferior/middle turbinates from the patients and inferior/middle turbinates from 13 patients undergoing nasal corrective surgery. EBV was the virus most frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and CMV (4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV was also detected in the adjacent turbinates (4%) and the adjacent middle turbinate (4%) of one of the HPV-positive patients. EBV, HSV, and CMV were not detected in the adjacent turbinates of the EBV-, HSV- or CMV-positive patients. All mucosae were negative for the VZV, HHV-6, and HHV-7. This is the first study to deal with the involvement of a comparable group of viruses in human nasal polyposis. The findings support the theory that the presence of viral EBV markedly influences the pathogenesis of these benign nasal tumors. The low incidence of HPV detected confirms the hypothesis that HPV is correlated with infectious mucosal lesions to a lesser extent than it is with proliferative lesions, such as inverted papilloma. The low incidence of HSV-1 and CMV confirms that these two herpes viruses may play a minor role in the development of nasal polyposis. Double infection with HSV-1 and CMV may also play a minor, though causative, role in nasal polyp development. . . VZV and HHV-6/-7 do not appear to be involved in the pathogenesis of these mucosal lesions.

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Thanks for sharing Joan. Where is Igenex located?

From: asfy <asfyso (DOT) fr>Subject: Epstein-Barr virussamters@groups .comDate: Tuesday, September 22, 2009, 2:15 AM

Has anyone here had an episode of infectious mononucleosis (Epstein-Barr virus) ?------------ -

J Med Virol. 2009 Sep;81(9):1613- 9. Links

Prevalence of human papilloma virus and human herpes virus types 1-7 in human nasal polyposis.

Zaravinos A, Bizakis J, Spandidos DA.

Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece.

This study aimed to investigate the prevalence of human papilloma virus (HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6/-7 (HHV-6/-7) in 23 human nasal polyps by applying PCR. Two types of control tissues were used: adjacent inferior/middle turbinates from the patients and inferior/middle turbinates from 13 patients undergoing nasal corrective surgery. EBV was the virus most frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and CMV (4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV was also detected in the adjacent turbinates (4%) and the adjacent middle turbinate (4%) of one of the HPV-positive patients. EBV, HSV, and CMV were not detected in the adjacent turbinates of the EBV-, HSV- or CMV-positive patients. All mucosae were negative for the VZV, HHV-6, and HHV-7. This is the first study

to deal with the involvement of a comparable group of viruses in human nasal polyposis. The findings support the theory that the presence of viral EBV markedly influences the pathogenesis of these benign nasal tumors. The low incidence of HPV detected confirms the hypothesis that HPV is correlated with infectious mucosal lesions to a lesser extent than it is with proliferative lesions, such as inverted papilloma. The low incidence of HSV-1 and CMV confirms that these two herpes viruses may play a minor role in the development of nasal polyposis. Double infection with HSV-1 and CMV may also play a minor, though causative, role in nasal polyp development.. . . VZV and HHV-6/-7 do not appear to be involved in the pathogenesis of these mucosal

lesions.

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Igenex is in Palo Alto.On Sep 22, 2009, at 8:05 PM, Jane Marino wrote: Thanks for sharing Joan. Where is Igenex located? From: asfy <asfyso (DOT) fr>Subject: Epstein-Barr virussamters@groups .comDate: Tuesday, September 22, 2009, 2:15 AM Has anyone here had an episode of infectious mononucleosis (Epstein-Barr virus) ?------------ - J Med Virol. 2009 Sep;81(9):1613- 9. Links Prevalence of human papilloma virus and human herpes virus types 1-7 in human nasal polyposis. Zaravinos A, Bizakis J, Spandidos DA. Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece. This study aimed to investigate the prevalence of human papilloma virus (HPV), herpes simplex virus-1/-2 (HSV-1/-2), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6/-7 (HHV-6/-7) in 23 human nasal polyps by applying PCR. Two types of control tissues were used: adjacent inferior/middle turbinates from the patients and inferior/middle turbinates from 13 patients undergoing nasal corrective surgery. EBV was the virus most frequently detected (35%), followed by HPV (13%), HSV-1 (9%), and CMV (4%). The CMV-positive polyp was simultaneously positive for HSV-1. HPV was also detected in the adjacent turbinates (4%) and the adjacent middle turbinate (4%) of one of the HPV-positive patients. EBV, HSV, and CMV were not detected in the adjacent turbinates of the EBV-, HSV- or CMV-positive patients. All mucosae were negative for the VZV, HHV-6, and HHV-7. This is the first study to deal with the involvement of a comparable group of viruses in human nasal polyposis. The findings support the theory that the presence of viral EBV markedly influences the pathogenesis of these benign nasal tumors. The low incidence of HPV detected confirms the hypothesis that HPV is correlated with infectious mucosal lesions to a lesser extent than it is with proliferative lesions, such as inverted papilloma. The low incidence of HSV-1 and CMV confirms that these two herpes viruses may play a minor role in the development of nasal polyposis. Double infection with HSV-1 and CMV may also play a minor, though causative, role in nasal polyp development.. . . VZV and HHV-6/-7 do not appear to be involved in the pathogenesis of these mucosal lesions.

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