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Aspirin Desensitization: Pre or post op

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I had densensitization at s Hopkins last Jan without sinus

surgery prior to the procedure and I will just say, it was not a

pleasant experiece. Because my sinsuses were so " volatile " since

they were completely full of polyps, I reacted serverely to all the

ASA doses and developed a major sinus infection. After a CT scan,

radiology and ENT were concerned the infection had moved into my

facial bones. It did not, thank goodness and sugery was performed

last July.

I reacted well to an eight week course of antifungal after surgery

since the polyps returned within two weeks, although I did not have

any sign of fungal sinusitis the drug had promising results at

MAYO. After eight weeks of Lamisil, I was told to take a two

week " drug holiday " and the polyps returned within 10 days. It took

office debridements, and Kenalog injections into the sinuses to get

me to Scripps in a pristine condition this past April. And all went

smoothly. Dr. son was grateful for the work ENT performed

since it made the desensitization much less eventful on his end.

Take care-

Barb V (nj)

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  • 3 weeks later...
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I want to know if anyone was taking Prednisone

before the Aspirin Desensitization. And how long after the Aspirin

Desensitization did you stop taking the Prednisone?

Thanks-

Rex

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I have taken Prednisone before desensitization.

My experience was that it greatly reduced the reaction, and made the process

less challenging. I think, however, that there have been previous posts on

this which question this observation. (note that my desensitizations have

been self-adminstered.)

I think most would agree, it can't hurt.

I wound down the prednisone as soon as desensitization was achieved, ie, in

about 3 days.

regards,

Ken West

416 654 1398

> From: Rex Young <rex@...>

> Reply-samters

> Date: Sun, 27 Jun 2004 09:03:15 -0700

> <samters >

> Subject: Aspirin Desensitization: Pre or post op

>

>

>

> I want to know if anyone was taking Prednisone before the Aspirin

> Desensitization. And how long after the Aspirin Desensitization did you stop

> taking the Prednisone?

>

>

>

> Thanks-

>

> Rex

>

>

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I, too, have taken prednisone before desensitization. I had to be on

it (50 milligrams a day at the time) to control my asthma. At

Scripps they will not let you into the study unless your asthma is

under control, and for me that took high doses of prednisone.

As soon as I was desensitized I was weaned off the steroids and for

the most part have rarely needed to be on steroids (and never at high

doses for any prolonged period of time) in the last nine years, seven

of which I was on the aspirin for, the last two I have not been. I

attribute this to both the aspirin desensitization and the advent of

new medications such as Advair and Singulair.

Hope this helps,

Lori

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