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Re: Methyl salicylate

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  • 3 months later...
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I didn't realize that methyl was a salicylate? Well, I guess that makes sense now.

Tami

Re:

LoriI have tried steaming my nose and from time to time, added Olbas oil, Vicks vapour rub, and tea tree oil. Since the vapour only is taken in, it seems quite safe. Is Oregano oil similar to any of these?Is there any evidence that breathing these oils could combat fungal sinus infections?.

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  • 3 years later...
Guest guest

>

> > Thank you so much for the information : I put some in my home-made lipstick,

> > I use it several times a day. I used wintergreen to pulp the lips, it works,

> > and never ever heard about that on french-lenguage information, nor with the

> > supplier. On the contrary, they pretend it is good to drain the organism, to

> > stimulate blood circulation, and only recommand high dilution for hepathic

> > problems.

> > If it is said on this professionnnal list that it is toxic, I get rid of it,

> > even if it was very diluted.

> > The fragrance and the taste was delightfull with cinnamom (verum or cassia)

> > and gingiber, I maybe use lemongrass..... or pink grapefruit

> >

> >

>

> In a review from the International Journal of toxicology published in 2003

> (the most recent publication on this topic), the conclusion from the

> authors was the methyl salicylate was safe in cosmetic dosages. Here is a

> good resource if you are interested in reading and drawing your own

> conclusions http://toxnet.nlm.nih.gov/

>

> Cory Trusty

> http://chinesetherapeutics.org

> Gifts and Healing Products:

> http://chinesetherapeutics.org/catalog/index.php

>

I have just been reading the review you refer to Cory. It's 108 pages long, has

over 400

references, I would say takes a very sensible, balanced view, and concludes that

methyl

salicylate (and hence wintergreen oil, sweet birch oil etc.) is safe to use on

the skin at up

to 0.6%. Before reading this review I had concluded from my own calculations

that MS was

safe to use at up to 0.2%.

I think it's important to recognize that there is a theoretical safe exposure

level for any

substance (even carcinogens), even though sometimes that level is so low that

it's not

practical. In the case of MS there are a number of liniment type products that

contain very

high concentrations - 12.8%, 20%, 25% etc. Such products should not be used

during

pregnancy, they are very dangerous if taken concurrently with a blood-thinning

drugs

such as warfarin, and there is a high risk of skin irritation.

By the way, it's my firm belief that the wintergreen oil coming out of Nepal is

totally

natural.

Tisserand

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Guest guest

> I have just been reading the review you refer to Cory. It's 108 pages long,

has over 400

> references, I would say takes a very sensible, balanced view, and concludes

that methyl

> salicylate (and hence wintergreen oil, sweet birch oil etc.) is safe to use on

the skin at up

> to 0.6%. Before reading this review I had concluded from my own calculations

that MS was

> safe to use at up to 0.2%.

>

> I think it's important to recognize that there is a theoretical safe exposure

level for any

> substance (even carcinogens), even though sometimes that level is so low that

it's not

> practical. In the case of MS there are a number of liniment type products that

contain very

> high concentrations - 12.8%, 20%, 25% etc. Such products should not be used

during

> pregnancy, they are very dangerous if taken concurrently with a blood-thinning

drugs

> such as warfarin, and there is a high risk of skin irritation.

>

> By the way, it's my firm belief that the wintergreen oil coming out of Nepal

is totally

> natural.

>

> Tisserand

Hi ,

I made my own calculation based on that abstract as well as another

abstract and my calculation that the safe concentration for twice a day

use is more like around 0.4%

This number is based on the suggested estimated toxic blood concentration

level of 0.3 mg/L in the review from the Int J Toxicology (2003;22 Suppl

3:1-108) together with clinical absorption rate study which included 2

topical dose over one week from the article in ls

Pharmacotherapy (VOL 30 ISS Sep 1996, P935-940).

For your reference here are my calculations:

12.5% methyl salicy X % max Methyl Sal. AKA wintergreen

------------------- = --------------------------------------------

blood level Cmax 6mg/L blood level Cmax 0.2 mg/L

max wintergreen per base salve for 2X/ day application: 0.4%

I'm still going to check these over with my pharmacist friend and see what

she thinks.

Cory Trusty

http://chinesetherapeutics.org

Gifts and Healing Products:

http://chinesetherapeutics.org/catalog/index.php

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Guest guest

>

>

> > I have just been reading the review you refer to Cory. It's 108 pages long,

has over

400

> > references, I would say takes a very sensible, balanced view, and concludes

that

methyl

> > salicylate (and hence wintergreen oil, sweet birch oil etc.) is safe to use

on the skin at

up

> > to 0.6%. Before reading this review I had concluded from my own calculations

that MS

was

> > safe to use at up to 0.2%.

> >

> > I think it's important to recognize that there is a theoretical safe

exposure level for

any

> > substance (even carcinogens), even though sometimes that level is so low

that it's not

> > practical. In the case of MS there are a number of liniment type products

that contain

very

> > high concentrations - 12.8%, 20%, 25% etc. Such products should not be used

during

> > pregnancy, they are very dangerous if taken concurrently with a

blood-thinning drugs

> > such as warfarin, and there is a high risk of skin irritation.

> >

> > By the way, it's my firm belief that the wintergreen oil coming out of Nepal

is totally

> > natural.

> >

> > Tisserand

>

> Hi ,

>

> I made my own calculation based on that abstract as well as another

> abstract and my calculation that the safe concentration for twice a day

> use is more like around 0.4%

>

> This number is based on the suggested estimated toxic blood concentration

> level of 0.3 mg/L in the review from the Int J Toxicology (2003;22 Suppl

> 3:1-108) together with clinical absorption rate study which included 2

> topical dose over one week from the article in ls

> Pharmacotherapy (VOL 30 ISS Sep 1996, P935-940).

>

> For your reference here are my calculations:

>

> 12.5% methyl salicy X % max Methyl Sal. AKA wintergreen

> ------------------- = --------------------------------------------

> blood level Cmax 6mg/L blood level Cmax 0.2 mg/L

>

> max wintergreen per base salve for 2X/ day application: 0.4%

>

> I'm still going to check these over with my pharmacist friend and see what

> she thinks.

>

> Cory Trusty

> http://chinesetherapeutics.org

> Gifts and Healing Products:

> http://chinesetherapeutics.org/catalog/index.php

>

Hi Cory,

Since suggesting a maximum of 0.2% methyl salicylate/wintergreen oil I came

accross

some good data that show maximum transdermal penetration to be 25% for MS. I had

assumed 50%, but revising that factor leads me to agree with your 0.4%, even

though from

a completely different calculation. Hopefully this finally answers the question.

Still on wintergreen, I received a private email challenging my assertion that

the oil from

Nepal was natural. I contacted beth Vossen, a Belgian supplier, and I think

her reply is

worth sharing:

Dear ,

It is nice to hear from you again after quite a while.

I can guarantee that our wintergreen oil is indeed 100% pure and natural oil

distilled from

the wintergreen plant. Wintergreen grows wild in Nepal and is collected in the

mountains

for steam distillation. Find herewith a picture of the plant taken by myself in

Lele, Nepal.

Our wintergreen oil is not composed of 100% methyl salicylate but contains 97 to

99.5%

depending on the lots. (but if analyzed by GC/MS the result will almost always

indicate

100% m/s)

Some of our customers prefer to buy " red wintergreen oil " to be sure that the

are not

buying synthetic methyl salicylate. We have both colourless oil (distilled in

stainless steel

distillation units) and red oil (the red colour comes from interaction with the

metal of the

distillation unit). Apparently there is no red synthetic methyl salicylate on

the market ...?

Anyway, there are no chemical factories in Nepal so they would not be able to

manufacture

synthetic methyl salicylate. What they have is good climate and lots of nature

(= wild,

organic plants) and know-how about distillation and ayurveda, and with the help

of crazy

people like us and some NGO's they have some good distillation units.

But I think the most convincing argument is that our wintergreen oil is

certified organic,

which means that the Ecocert and SKAL/Control Union inspectors from Europe and

India

have visited the collection areas and distillation units and have checked all

the records and

accounts (quantity of raw material collected versus number of vessels distilled

versus

quantity of oil produced versus quantity of oil exported from Nepal versus

quantity of oil

imported in Belgium versus quantity of oil invoiced to customers).

Of course if all this is not convincing, you are most welcome to visit the

distillation units in

Nepal where we distill the wintergreen. If I am not mistaken, the collection and

distillation

is being done all year round, except when there is too much snow in the high

mountains.

Lele is about 4 hours drive from Kathmandu so it's quite easy to reach.

I hope this helps to convince your colleagues. Don't hesitate to ask more if

needed.

Best regards,

beth

Sounds good to me.

Tisserand

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