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Antifungals in a nasal wash

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Besides Amphotericin B has anyone used any non RX antifungal treatments in a

nasal wash with success? Tami ,I read your post this year concerning the Mayo

clinic protocol,with dissapointment..I'm thinking of naturally occuring

substances ,for example vinegar or apple cider vinegar,garlic ,or OTC products

etc.I guess I am suspect of an Ent's ability to do any proper culturing of

fungus or anaerobic bacteria for that matter.

My maxillary sinuses are heavily involved with calcific changes and clearly

aren't anywhere near normal, yet all I have encountered is a reluctance in

treating them.The changes are consistent with fungal involvement so I wish to

explore the antifungal approach topically .I still believe my maxillary sinuses

need to be treated. I cannot believe that treating say the frontals or ethmoids

and neglecting involved sphenoids or maxillary sinuses is sound treatment.Also

it's nice to see some histopathology as related to Samter's ( as Ponikeau does)

as this seems to have been neglected in most reviews of AERD.

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I'd rather find a good lab willing to culture whathever brown thing comes out before attempting any treatment, as fungi can become resistant to medication. Besides, irrigating with dilute vinegar will burn. Someone last year said they used H2O2 successfully to get rid of molds in their home, so it's likely efficient, but it may burn too.I suppose a surgeon operating on frontals would also give a brief look to the maxillaries to check ostium patency and have a look inside to see if everything looks normal, but he may also overlook it.Ponikau does believe in fungal involvement, but may also have a tendency to see them everywhere. From what I understand, fungal infections do happen, but less frequently than bacterial ones. Suspicion can arise when there is brown to black material coming out, or when something like a fungal ball appears on the CT. Then, it's endoscopy to check.>> > > Besides Amphotericin B has anyone used any non RX antifungal treatments in a nasal wash with success? Tami ,I read your post this year concerning the Mayo clinic protocol,with dissapointment..I'm thinking of naturally occuring substances ,for example vinegar or apple cider vinegar,garlic ,or OTC products etc.I guess I am suspect of an Ent's ability to do any proper culturing of fungus or anaerobic bacteria for that matter.> My maxillary sinuses are heavily involved with calcific changes and clearly aren't anywhere near normal, yet all I have encountered is a reluctance in treating them.The changes are consistent with fungal involvement so I wish to explore the antifungal approach topically .I still believe my maxillary sinuses need to be treated. I cannot believe that treating say the frontals or ethmoids and neglecting involved sphenoids or maxillary sinuses is sound treatment.Also it's nice to see some histopathology as related to Samter's ( as Ponikeau does) as this seems to have been neglected in most reviews of AERD.>

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Supposing a positive result from a lab specimen what viable antifungal

treatments are out there besides surgery and corticosteroids?

> >

> >

> >

> > Besides Amphotericin B has anyone used any non RX antifungal

> treatments in a nasal wash with success? Tami ,I read your post this

> year concerning the Mayo clinic protocol,with dissapointment..I'm

> thinking of naturally occuring substances ,for example vinegar or apple

> cider vinegar,garlic ,or OTC products etc.I guess I am suspect of an

> Ent's ability to do any proper culturing of fungus or anaerobic bacteria

> for that matter.

> > My maxillary sinuses are heavily involved with calcific changes and

> clearly aren't anywhere near normal, yet all I have encountered is a

> reluctance in treating them.The changes are consistent with fungal

> involvement so I wish to explore the antifungal approach topically .I

> still believe my maxillary sinuses need to be treated. I cannot believe

> that treating say the frontals or ethmoids and neglecting involved

> sphenoids or maxillary sinuses is sound treatment.Also it's nice to see

> some histopathology as related to Samter's ( as Ponikeau does) as this

> seems to have been neglected in most reviews of AERD.

> >

>

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There are a good number of antifungals out there, but you would have to make a quick research based on the fungal type to see to what it is currently sensitive. Don't overuse steroids on fungi, for fear of depressing immunity to a point where the fungi can become invasive - which is of poor prognosis (but this usually happens in immune-depressed patients, ie diabetic, etc).> > >> > >> > >> > > Besides Amphotericin B has anyone used any non RX antifungal> > treatments in a nasal wash with success? Tami ,I read your post this> > year concerning the Mayo clinic protocol,with dissapointment..I'm> > thinking of naturally occuring substances ,for example vinegar or apple> > cider vinegar,garlic ,or OTC products etc.I guess I am suspect of an> > Ent's ability to do any proper culturing of fungus or anaerobic bacteria> > for that matter.> > > My maxillary sinuses are heavily involved with calcific changes and> > clearly aren't anywhere near normal, yet all I have encountered is a> > reluctance in treating them.The changes are consistent with fungal> > involvement so I wish to explore the antifungal approach topically .I> > still believe my maxillary sinuses need to be treated. I cannot believe> > that treating say the frontals or ethmoids and neglecting involved> > sphenoids or maxillary sinuses is sound treatment.Also it's nice to see> > some histopathology as related to Samter's ( as Ponikeau does) as this> > seems to have been neglected in most reviews of AERD.> > >> >>

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