[SPAM] Re: Re: New to the group and lost

[Guest guest]

Did someone say that they took Singular and Zyflo together?

-- [sPAM] Re: Re: New to the group and lost

LOL, -- yes, it's leukotrienes.

Glad the yoga and Zyflo is working for you!

Lori

[Guest guest]

I do. Singulair 10 1x a day and Zyflo 4x a day. Have even discussed

increasing Singulair dosage beyond the on-label 10mg a day, but as I am

feeling very good at this time and given that my insurance company is likely

to disapprove the cost, my doc and I have elected to stay at the 10mg for

the moment.

As I understand it, one reduces production the other uptake so the two

should work well together.

ie

[Guest guest]

I am taking zyflo and singulair together. I used that combination

before with fairly good results, but I would still have severe

reactions to things unknown (perfumes, foods, the air in my office)

In 2003 I did asa desensitization with excellent results. Since then

I was using irrigation, allegra, singulair,nasal and inhaled steroids

with good results. This winter, I had another ( number 6or 7 )sinus

surgery because of an obstructing polyp causing severe problems with

sinusits. I did well but in March, I began to have problems with

hearing loss and pain with persistent serous otitis. I used several

course of steroids but the problem persisted. I tried adding zyflo

again with excellent results. I am doing much better with restored

hearing, and decreased tinnitus and rhinorrhea. I have continued the

singulair and ASA as I have not had the sudden unexplained severe

reactions.

I suspect the mechanism is that I produce phenomenal amounts of

leukotrienes and the ASA down regulates the production as does the

zyflo ( a 5-lipooxygenase inhibitor) whereas singulair is a receptor

blocker. Zyflo and ASA desensitization work on some of the

leukotrienes that singulair does not effect. Note, I have bad

allergies and asthma and have had problems since I was 3. I am now 60.

Interestingly, my husband who is a pediatric endocrinologist was at a

diabetes meeting heard a presentation about using a combination of an

Angiotension Converting enzyme (ACE) inhibitor combined with a

receptor blocker in preventing renal disease in some severe diabetics

and a higher response rate was seen. The use of zyflo and singulair

would be analogous.

I was also amazed at the price increase in zyflo since it was

reintroduced.

>

> Did someone say that they took Singular and Zyflo together?

>

> -- [sPAM] Re: Re: New to the group and lost

>

> LOL, -- yes, it's leukotrienes.

>

> Glad the yoga and Zyflo is working for you!

>

> Lori