Guest guest Posted January 20, 2010 Report Share Posted January 20, 2010 Joan, Mine are ALWAYS quite high. However, yours are REALLY high. Let us know what your doctor says! Jane From: joan harvey <thomyris7@...>Subject: high eosinophils?samters Date: Wednesday, January 20, 2010, 7:31 PM I just got some lab test results and my "absolute eosinophils" are off the charts -- normal range 0-500 -- mine were 3236. I think high eosinophils are a component of Samter's? Just wondering if anyone knows anything as I'm going to see a new general practitioner and sometimes they don't know about Samter's. Various other things look way high as well, but I assume they may have to do with infection rather than Samter's itself. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 According to my GP high EOS is an indication of allergies and definitely Samters would be included. My blood test was a little different in that it measured EOS%. Initially mine was 11.8% which was considered high. I was able to reduce this number to 1.6% by taking Niacin (Vitamin which is available over-the-counter. Additionally after taking Niacin my Homocysteine Plasma level dropped from 15.5, which is considered high, to 9.7 which is in the normal range. And finally my LDL Cholesterol dropped to 60 from 106. To me it was impressive that all of this could be accomplished with a medication that costs about $8.00 per month. high eosinophils? I just got some lab test results and my " absolute eosinophils " are off the charts -- normal range 0-500 -- mine were 3236. I think high eosinophils are a component of Samter's? Just wondering if anyone knows anything as I'm going to see a new general practitioner and sometimes they don't know about Samter's. Various other things look way high as well, but I assume they may have to do with infection rather than Samter's itself. ------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 Thanks . I think I have some Niacin somewhere in the masses of supplements I have bought and abandoned over the years. After reading your post I'm going to start taking it right away. My LDL cholesterol is low, as is the CHOL/HDL ratio, but my triglycerides are way high (and a bunch of other things). Don't think I had Homocysteine plasma checked. Thanks again for the info.JoanOn Jan 21, 2010, at 1:44 PM, Ekren wrote: According to my GP high EOS is an indication of allergies and definitely Samters would be included. My blood test was a little different in that it measured EOS%. Initially mine was 11.8% which was considered high. I was able to reduce this number to 1.6% by taking Niacin (Vitamin which is available over-the-counter. Additionally after taking Niacin my Homocysteine Plasma level dropped from 15.5, which is considered high, to 9.7 which is in the normal range. And finally my LDL Cholesterol dropped to 60 from 106. To me it was impressive that all of this could be accomplished with a medication that costs about $8.00 per month. high eosinophils? I just got some lab test results and my "absolute eosinophils" are off the charts -- normal range 0-500 -- mine were 3236. I think high eosinophils are a component of Samter's? Just wondering if anyone knows anything as I'm going to see a new general practitioner and sometimes they don't know about Samter's. Various other things look way high as well, but I assume they may have to do with infection rather than Samter's itself. ------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 Hello Joan, A large number of reasons may explain high eosinophils, see : http://emedicine.medscape.com/article/886861-overview In the context of Samter's, AERDs usually correspond to elevated eosinophils. However, this can also arise indirectly from treatment ; for instance, Zafirlukast (a leukotriene inhibitor) was found to give hypereosinophilia : http://docs.google.com/viewer?a=v & q=cache:rAoNum1YVAAJ:www.jiaci.org/iss\ ues/vol16issue01/12.pdf+aspirin+hypereosinophilia & hl=fr & gl=fr & sig=AHIEtb\ RbX2SQz1xwZX_h5PYrsCIJqaw2Qw It would therefore be interesting to monitor very closely your eosinophil levels to compare them to previous levels, and see what happens when one drug or the other is discontinued. Whathever the cause, significant hypereosinophilia must not be left untreated. > > I just got some lab test results and my " absolute eosinophils " are off the charts -- normal range 0-500 -- mine were 3236. I think high eosinophils are a component of Samter's? Just wondering if anyone knows anything as I'm going to see a new general practitioner and sometimes they don't know about Samter's. Various other things look way high as well, but I assume they may have to do with infection rather than Samter's itself. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 Thanks, asfy. I'm not really on any drugs except aspirin (though I just started a course of Bactrim for a sinus infection -- I find it to be incredibly dehydrating -- don't know if I can handle it esp at night, but am going to give it a go). So I don't think it could be related to that. Could a severe sinus infection cause higher eosinophil levels? I've tested negative for environmental and food allergies and am on a quite careful diet at the moment as I have been quite ill. I had more blood work done on Friday -- as lots of other factors were too high -- to see if the results are the same. I should find out next week. I'm starting to feel better so maybe it was some sort short acute illness. On Jan 24, 2010, at 8:04 AM, asfy wrote: Hello Joan, A large number of reasons may explain high eosinophils, see : http://emedicine.medscape.com/article/886861-overview In the context of Samter's, AERDs usually correspond to elevated eosinophils. However, this can also arise indirectly from treatment ; for instance, Zafirlukast (a leukotriene inhibitor) was found to give hypereosinophilia : http://docs.google.com/viewer?a=v & q=cache:rAoNum1YVAAJ:www.jiaci.org/iss\ ues/vol16issue01/12.pdf+aspirin+hypereosinophilia & hl=fr & gl=fr & sig=AHIEtb\ RbX2SQz1xwZX_h5PYrsCIJqaw2Qw It would therefore be interesting to monitor very closely your eosinophil levels to compare them to previous levels, and see what happens when one drug or the other is discontinued. Whathever the cause, significant hypereosinophilia must not be left untreated. > > I just got some lab test results and my "absolute eosinophils" are off the charts -- normal range 0-500 -- mine were 3236. I think high eosinophils are a component of Samter's? Just wondering if anyone knows anything as I'm going to see a new general practitioner and sometimes they don't know about Samter's. Various other things look way high as well, but I assume they may have to do with infection rather than Samter's itself. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 24, 2010 Report Share Posted January 24, 2010 A lot of conditions can increase eosinophils, with parasitic infestation being a classical situation.However, in our case, it should be mentioned that desensitization itself can raise the eosinophils (there is no abstract available, just see the title). This is not inconsistent with the fact that aspirin desensitization does not suppress the Samter's reaction itself, but rather that it makes one less sensitive to it (some believe it "numbs" the leukotriene receptors).So, to check out this possibility, monitor your eosinophils under different aspirin dosages and see if lowering the dose also lowers the eosinophils.--------------- Journal of Allergy and Clinical Immunology Volume 119, Issue 1, Supplement 1, January 2007, Page S39 Program and Abstracts of Papers to be Presented During Scientific Sessions - 2007 AAAAI Annual Meeting, 2007 AAAAI Annual Meeting doi:10.1016/j.jaci.2006.11.174 | How to Cite or Link Using DOI Copyright © 2007 American Academy of Allergy, Asthma & Immunology Published by Mosby, Inc. Persistent Eosinophilia Following Aspirin Desensitization in a Patient with Aspirin Exacerbated Respiratory Disease References and further reading may be available for this article. To view references and further reading you must purchase this article. N.M. Vogela, D.M. Langa and F.H. Hsieha aThe Cleveland Clinic Foundation, Cleveland, OH 152. Available online 9 January 2007. > > >> > > I just got some lab test results and my "absolute eosinophils" are off> > the charts -- normal range 0-500 -- mine were 3236. I think high> > eosinophils are a component of Samter's? Just wondering if anyone knows> > anything as I'm going to see a new general practitioner and sometimes> > they don't know about Samter's. Various other things look way high as> > well, but I assume they may have to do with infection rather than> > Samter's itself.> > >> > > >> Quote Link to comment Share on other sites More sharing options...
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