Zyflo

[Guest guest]

Hi Lori:

I'm the other Lori who also takes Zyflo with great success. I take it together with accolate. Both seem to work better for me than just taking one. I do know when I miss a dose becuase I start having my symtoms again. However, they subside when I take my pill.

Has anyone been desen. to aspirin and taken zyflo while doing so. I was desen about 4 years ago. I had to go off the aspirin because I was having lots of sneezing problems. I think if I go back and become desen. while taking zyflo, my symtoms would lessen.

Lori B.

Zyflo

Hi Arch,I can't remember what I posted about Zyflo, or is there another Lori here,too? I think maybe I was wondering if it IS available in Europe, because Iwill be moving there in the next few years. I also am having good successwith Zyflo, am worried a little about the possible liver problems; will begoing in soon for my liver enzyme tests to make sure I'm doing okay. Makesure you get those if you haven't!! It's important. I hope Zyfloeventually does become approved over there.I have the same thing you do, because it is metabolized SO fast, if youdon't time it right your symptoms come back. I think it will be reallyhelpful after I get cleaned out again with surgery.By the way, off topic, I noticed your name, "oubliette." Interesting. Acomposer wrote a song for me of that name. : )Lori

[Guest guest]

About two months ago I was told that Zyflo was taken off the market,

however, I am now told it is coming back. I have an appt with my Doc on

Thursday and will find out - will let you know

Zyflo

> Anyone using zyflo? It's been discontinued by Abbott, but am

> interested in finding some for continued use. Any ideas?

>

>

>

>

>

[Guest guest]

Hi ?,

I am not taking Zyflo but several on this list are or were. Some were

able to get a supply before they took it off the market. There is

also a thread about it being put back on the market but it will be

manufactured by a different company and reformulated to be taken

twice daily instead of 4 x's daily. You can read about it on the

Samter's website: samters/

Go to " Messages " on the left hand side of the home page. When that

page comes up, look up in the right hand corner of that page & you

will seed a little, bittly box with Msg #, then a small space. Type

2888 in that small space, hit " Go " and you can read the thread. Or

just type in " Zyflo Lives " in the Search Archives line.

in NM

> Anyone using zyflo? It's been discontinued by Abbott, but am

> interested in finding some for continued use. Any ideas?

[Guest guest]

Hi, All:

Does someone have any updates on Zyflo? When will it become

available? My doctor in National Jewish Denver subscribed Zyflo for

me, I've been take them for over 5 years now, it has been worked out

great! better than Singulair (to me). If you have any info about it

please drop a line. Thanks.

hk

> Tammy. Below is a copy/paste that describes the role of Singulair

pretty

> good. The med blocks leukotrienes. I started taking it last

August and now

> question if I need nasal spray at all. Takes a couple days to

build up in the

> body if you have a lot of congestion. My allergy tests didn't

show anything but

> I recently stopped Singulair and made a list of things to stop

based on

> " possible " reactions. Soon I'll stop taking Singulair again and

start taking things

> one at a time to see what happens and hopefully pin down the

cause. Right

> now my list includes aspirin, milk and alcohol. What I found

interesting with

> milk is you can have a delayed reaction that won't show up on an

allergy test.

> So I'll let my nose be the judge. Also, there's a difference

between lactose

> intolerance and a milk allergy. I hope not..I love milk. Think

there are

> tests available for delayed reaction stuff. I hope it's not

aspirin either but

> I'm learning a lot from this board.

> in Arizona

>

> LEUKOTRIENE-RECEPTOR ANTAGONISTS

> e.g. montelukast sodium (Singulair)

> Leukotrienes are potent bronchoconstrictors and cause airway wall

oedema,

> increasing mucus production. Leukotrienes also attract eosinophils

into the

> tissues and amplify the inflammatory process. Leukotriene

antagonists specifically

> inhibit the production or actions of the inflammatory mediators

(leukotrienes

> C4 and D4).

> The precise role of these medications in asthma is still being

determined.

> However, they are likely to be useful as preventive treatment in

mild asthma as

> an alternative to low doses of inhaled corticosteroids (potency

equivalent to

> about 400mcg of BDP (CFC)); they may allow the dose of

corticosteroids to be

> reduced in moderate asthma; and they may help in stabilising

people with more

> severe disease29. They are likely to be useful in specific

subtypes of asthma

> such as aspirin-sensitive asthma and exercise-induced asthma. The

response to

> treatment is variable.

> Montelukast is a once-daily tablet that is well tolerated in

children and

> confers a modest benefit in frequent episodic or mild persistent

asthma. It

> appears to be very effective in providing prolonged protection

from

> exercise-induced asthma.

> The advantages of leukotriene receptor antagonists are that: they

are oral

> medications taken once or twice a day they treat asthma via a

completely

> different pathway to other currently available medications.

> They are preventive medications and do not provide immediate

benefit for

> acute episodes of asthma. They are not as effective as inhaled

LABAs as adjunctive

> therapy to ICS.

> Indications include: prevention of day and night-time symptoms

treatment of

> aspirin-sensitive asthma patients prevention of exercise-induced

> bronchoconstriction as adjunctive therapy when ICS or LABAs are

not tolerated.

> Note that therapy should normally be continued during acute

exacerbations of

> asthma, and therapy should not be substituted abruptly for inhaled

or oral

> corticosteroids.

[Guest guest]

The drug will begin regular production later this year. In the

meantime, you can go here:

http://criticaltherapeutics.com/zyflo_study.html

to be part of a phase IIIb of the drug with your doctor.

On Wed, 23 Mar 2005 20:10:33 -0000, hk2camp <hk2camp@...> wrote:

>

>

> Hi, All:

>

> Does someone have any updates on Zyflo? When will it become

> available? My doctor in National Jewish Denver subscribed Zyflo for

> me, I've been take them for over 5 years now, it has been worked out

> great! better than Singulair (to me). If you have any info about it

> please drop a line. Thanks.

>

> hk

>

>

> > Tammy. Below is a copy/paste that describes the role of Singulair

> pretty

> > good. The med blocks leukotrienes. I started taking it last

> August and now

> > question if I need nasal spray at all. Takes a couple days to

> build up in the

> > body if you have a lot of congestion. My allergy tests didn't

> show anything but

> > I recently stopped Singulair and made a list of things to stop

> based on

> > " possible " reactions. Soon I'll stop taking Singulair again and

> start taking things

> > one at a time to see what happens and hopefully pin down the

> cause. Right

> > now my list includes aspirin, milk and alcohol. What I found

> interesting with

> > milk is you can have a delayed reaction that won't show up on an

> allergy test.

> > So I'll let my nose be the judge. Also, there's a difference

> between lactose

> > intolerance and a milk allergy. I hope not..I love milk. Think

> there are

> > tests available for delayed reaction stuff. I hope it's not

> aspirin either but

> > I'm learning a lot from this board.

> > in Arizona

> >

> > LEUKOTRIENE-RECEPTOR ANTAGONISTS

> > e.g. montelukast sodium (Singulair)

> > Leukotrienes are potent bronchoconstrictors and cause airway wall

> oedema,

> > increasing mucus production. Leukotrienes also attract eosinophils

> into the

> > tissues and amplify the inflammatory process. Leukotriene

> antagonists specifically

> > inhibit the production or actions of the inflammatory mediators

> (leukotrienes

> > C4 and D4).

> > The precise role of these medications in asthma is still being

> determined.

> > However, they are likely to be useful as preventive treatment in

> mild asthma as

> > an alternative to low doses of inhaled corticosteroids (potency

> equivalent to

> > about 400mcg of BDP (CFC)); they may allow the dose of

> corticosteroids to be

> > reduced in moderate asthma; and they may help in stabilising

> people with more

> > severe disease29. They are likely to be useful in specific

> subtypes of asthma

> > such as aspirin-sensitive asthma and exercise-induced asthma. The

> response to

> > treatment is variable.

> > Montelukast is a once-daily tablet that is well tolerated in

> children and

> > confers a modest benefit in frequent episodic or mild persistent

> asthma. It

> > appears to be very effective in providing prolonged protection

> from

> > exercise-induced asthma.

> > The advantages of leukotriene receptor antagonists are that: they

> are oral

> > medications taken once or twice a day they treat asthma via a

> completely

> > different pathway to other currently available medications.

> > They are preventive medications and do not provide immediate

> benefit for

> > acute episodes of asthma. They are not as effective as inhaled

> LABAs as adjunctive

> > therapy to ICS.

> > Indications include: prevention of day and night-time symptoms

> treatment of

> > aspirin-sensitive asthma patients prevention of exercise-induced

> > bronchoconstriction as adjunctive therapy when ICS or LABAs are

> not tolerated.

> > Note that therapy should normally be continued during acute

> exacerbations of

> > asthma, and therapy should not be substituted abruptly for inhaled

> or oral

> > corticosteroids.

>

>

>

>

[Guest guest]

,

Did you get any feedback from your doctor re: Zyflo phase III? They keep changing their release date. My allergist just returned from a medical conference and he said Zyflo had several booths but couldnt get a definite date. Are you still going to do the desens? I am scheduled for June, I will be doing it as an outpatient, three days going home at night. He seems to think that once I do the desens I wont need the zyflo.

(TX)

Condouris <condour@...> wrote:

The drug will begin regular production later this year. In themeantime, you can go here:http://criticaltherapeutics.com/zyflo_study.htmlto be part of a phase IIIb of the drug with your doctor.On Wed, 23 Mar 2005 20:10:33 -0000, hk2camp <hk2camp@...> wrote:> > > Hi, All:> > Does someone have any updates on Zyflo? When will it become> available? My doctor in National Jewish Denver subscribed Zyflo for> me, I've been take them for over 5 years now, it has been worked out> great! better than Singulair (to me). If you have any info about it> please drop a line. Thanks.> > hk> > > > Tammy. Below is a

copy/paste that describes the role of Singulair> pretty> > good. The med blocks leukotrienes. I started taking it last> August and now> > question if I need nasal spray at all. Takes a couple days to> build up in the> > body if you have a lot of congestion. My allergy tests didn't> show anything but> > I recently stopped Singulair and made a list of things to stop> based on> > "possible" reactions. Soon I'll stop taking Singulair again and> start taking things> > one at a time to see what happens and hopefully pin down the> cause. Right> > now my list includes aspirin, milk and alcohol. What I found> interesting with> > milk is you can have a delayed reaction that won't show up on an> allergy test.> > So I'll let my nose be the judge. Also, there's a difference> between

lactose> > intolerance and a milk allergy. I hope not..I love milk. Think> there are> > tests available for delayed reaction stuff. I hope it's not> aspirin either but> > I'm learning a lot from this board.> > in Arizona> >> > LEUKOTRIENE-RECEPTOR ANTAGONISTS> > e.g. montelukast sodium (Singulair)> > Leukotrienes are potent bronchoconstrictors and cause airway wall> oedema,> > increasing mucus production. Leukotrienes also attract eosinophils> into the> > tissues and amplify the inflammatory process. Leukotriene> antagonists specifically> > inhibit the production or actions of the inflammatory mediators> (leukotrienes> > C4 and D4).> > The precise role of these medications in asthma is still being> determined.> > However, they are likely to be useful as preventive treatment

in> mild asthma as> > an alternative to low doses of inhaled corticosteroids (potency> equivalent to> > about 400mcg of BDP (CFC)); they may allow the dose of> corticosteroids to be> > reduced in moderate asthma; and they may help in stabilising> people with more> > severe disease29. They are likely to be useful in specific> subtypes of asthma> > such as aspirin-sensitive asthma and exercise-induced asthma. The> response to> > treatment is variable.> > Montelukast is a once-daily tablet that is well tolerated in> children and> > confers a modest benefit in frequent episodic or mild persistent> asthma. It> > appears to be very effective in providing prolonged protection> from> > exercise-induced asthma.> > The advantages of leukotriene receptor antagonists are that: they> are oral> > medications

taken once or twice a day they treat asthma via a> completely> > different pathway to other currently available medications.> > They are preventive medications and do not provide immediate> benefit for> > acute episodes of asthma. They are not as effective as inhaled> LABAs as adjunctive> > therapy to ICS.> > Indications include: prevention of day and night-time symptoms> treatment of> > aspirin-sensitive asthma patients prevention of exercise-induced> > bronchoconstriction as adjunctive therapy when ICS or LABAs are> not tolerated.> > Note that therapy should normally be continued during acute> exacerbations of> > asthma, and therapy should not be substituted abruptly for inhaled> or oral> > corticosteroids.> > > >

[Guest guest]

I'm seeing a doctor in New York about IIIb, and potentially

desensitization. My regular guy didn't want to touch the 3b, since it

requires a great deal of paperwork, and effects of the drug isn't

covered by his regular malpractice insurance (though I believe the

company does cover it)

I don't think there's a definite date but I think the target for

regular availability is around September.

On Wed, 23 Mar 2005 15:22:23 -0800 (PST), Garfield

<scooterlu2002@...> wrote:

>

> ,

>

> Did you get any feedback from your doctor re: Zyflo phase III? They keep

> changing their release date. My allergist just returned from a medical

> conference and he said Zyflo had several booths but couldnt get a definite

> date. Are you still going to do the desens? I am scheduled for June, I

> will be doing it as an outpatient, three days going home at night. He seems

> to think that once I do the desens I wont need the zyflo.

>

> (TX)

>

>

> Condouris <condour@...> wrote:

> The drug will begin regular production later this year. In the

> meantime, you can go here:

>

> http://criticaltherapeutics.com/zyflo_study.html

>

> to be part of a phase IIIb of the drug with your doctor.

>

>

> On Wed, 23 Mar 2005 20:10:33 -0000, hk2camp <hk2camp@...> wrote:

> >

> >

> > Hi, All:

> >

> > Does someone have any updates on Zyflo? When will it become

> > available? My doctor in National Jewish Denver subscribed Zyflo for

> > me, I've been take them for over 5 years now, it has been worked out

> > great! better than Singulair (to me). If you have any info about it

> > please drop a line. Thanks.

> >

> > hk

> >

> >

> > > Tammy. Below is a copy/paste that describes the role of Singulair

> > pretty

> > > good. The med blocks leukotrienes. I started taking it last

> > August and now

> > > question if I need nasal spray at all. Takes a couple days to

> > build up in the

> > > body if you have a lot of congestion. My allergy tests didn't

> > show anything but

> > > I recently stopped Singulair and made a list of things to stop

> > based on

> > > " possible " reactions. Soon I'll stop taking Singulair again and

> > start taking things

> > > one at a time to see what happens and hopefully pin down the

> > cause. Right

> > > now my list includes aspirin, milk and alcohol. What I found

> > interesting with

> > > milk is you can have a delayed reaction that won't show up on an

> > allergy test.

> > > So I'll let my nose be the judge. Also, there's a difference

> > between lactose

> > > intolerance and a milk allergy. I hope not..I love milk. Think

> > there are

> > > tests available for delayed reaction stuff. I hope it's not

> > aspirin either but

> > > I'm learning a lot from this board.

> > > in Arizona

> > >

> > > LEUKOTRIENE-RECEPTOR ANTAGONISTS

> > > e.g. montelukast sodium (Singulair)

> > > Leukotrienes are potent bronchoconstrictors and cause airway wall

> > oedema,

> > > increasing mucus production. Leukotrienes also attract eosinophils

> > into the

> > > tissues and amplify the inflammatory process. Leukotriene

> > antagonists specifically

> > > inhibit the production or actions of the inflammatory mediators

> > (leukotrienes

> > > C4 and D4).

> > > The precise role of these medications in asthma is still being

> > determined.

> > > However, they are likely to be useful as preventive treatment in

> > mild asthma as

> > > an alternative to low doses of inhaled corticosteroids (potency

> > equivalent to

> > > about 400mcg of BDP (CFC)); they may allow the dose of

> > corticosteroids to be

> > > reduced in moderate asthma; and they may help in stabilising

> > people with more

> > > severe disease29. They are likely to be useful in specific

> > subtypes of asthma

> > > such as aspirin-sensitive asthma and exercise-induced asthma. The

> > response to

> > > treatment is variable.

> > > Montelukast is a once-daily tablet that is well tolerated in

> > children and

> > > confers a modest benefit in frequent episodic or mild persistent

> > asthma. It

> > > appears to be very effective in providing prolonged protection

> > from

> > > exercise-induced asthma.

> > > The advantages of leukotriene receptor antagonists are that: they

> > are oral

> > > medications taken once or twice a day they treat asthma via a

> > completely

> > > different pathway to other currently available medications.

> > > They are preventive medications and do not provide immediate

> > benefit for

> > > acute episodes of asthma. They are not as effective as inhaled

> > LABAs as adjunctive

> > > therapy to ICS.

> > > Indications include: prevention of day and night-time symptoms

> > treatment of

> > > aspirin-sensitive asthma patients prevention of exercise-induced

> > > bronchoconstriction as adjunctive therapy when ICS or LABAs are

> > not tolerated.

> > > Note that therapy should normally be continued during acute

> > exacerbations of

> > > asthma, and therapy should not be substituted abruptly for inhaled

> > or oral

> > > corticosteroids.

> >

> >

> >

> >

[Guest guest]

Thanks a lot ! I'll check the link, too.

Also, about 7 years ago, my doctor in SF Bay Area sent me to

National Jewish in Denver. There I met Dr. Sally Wenzel. Since then

I'm no longer on steroids! I'm working full time; being able to do

outdoor activities. To me, National Jewish is the place to go!

hp

> > > > Tammy. Below is a copy/paste that describes the role of

Singulair

> > > pretty

> > > > good. The med blocks leukotrienes. I started taking it last

> > > August and now

> > > > question if I need nasal spray at all. Takes a couple days

to

> > > build up in the

> > > > body if you have a lot of congestion. My allergy tests

didn't

> > > show anything but

> > > > I recently stopped Singulair and made a list of things to

stop

> > > based on

> > > > " possible " reactions. Soon I'll stop taking Singulair again

and

> > > start taking things

> > > > one at a time to see what happens and hopefully pin down the

> > > cause. Right

> > > > now my list includes aspirin, milk and alcohol. What I found

> > > interesting with

> > > > milk is you can have a delayed reaction that won't show up

on an

> > > allergy test.

> > > > So I'll let my nose be the judge. Also, there's a difference

> > > between lactose

> > > > intolerance and a milk allergy. I hope not..I love milk.

Think

> > > there are

> > > > tests available for delayed reaction stuff. I hope it's not

> > > aspirin either but

> > > > I'm learning a lot from this board.

> > > > in Arizona

> > > >

> > > > LEUKOTRIENE-RECEPTOR ANTAGONISTS

> > > > e.g. montelukast sodium (Singulair)

> > > > Leukotrienes are potent bronchoconstrictors and cause airway

wall

> > > oedema,

> > > > increasing mucus production. Leukotrienes also attract

eosinophils

> > > into the

> > > > tissues and amplify the inflammatory process. Leukotriene

> > > antagonists specifically

> > > > inhibit the production or actions of the inflammatory

mediators

> > > (leukotrienes

> > > > C4 and D4).

> > > > The precise role of these medications in asthma is still

being

> > > determined.

> > > > However, they are likely to be useful as preventive

treatment in

> > > mild asthma as

> > > > an alternative to low doses of inhaled corticosteroids

(potency

> > > equivalent to

> > > > about 400mcg of BDP (CFC)); they may allow the dose of

> > > corticosteroids to be

> > > > reduced in moderate asthma; and they may help in stabilising

> > > people with more

> > > > severe disease29. They are likely to be useful in specific

> > > subtypes of asthma

> > > > such as aspirin-sensitive asthma and exercise-induced

asthma. The

> > > response to

> > > > treatment is variable.

> > > > Montelukast is a once-daily tablet that is well tolerated in

> > > children and

> > > > confers a modest benefit in frequent episodic or mild

persistent

> > > asthma. It

> > > > appears to be very effective in providing prolonged

protection

> > > from

> > > > exercise-induced asthma.

> > > > The advantages of leukotriene receptor antagonists are that:

they

> > > are oral

> > > > medications taken once or twice a day they treat asthma via a

> > > completely

> > > > different pathway to other currently available medications.

> > > > They are preventive medications and do not provide immediate

> > > benefit for

> > > > acute episodes of asthma. They are not as effective as

inhaled

> > > LABAs as adjunctive

> > > > therapy to ICS.

> > > > Indications include: prevention of day and night-time

symptoms

> > > treatment of

> > > > aspirin-sensitive asthma patients prevention of exercise-

induced

> > > > bronchoconstriction as adjunctive therapy when ICS or LABAs

are

> > > not tolerated.

> > > > Note that therapy should normally be continued during acute

> > > exacerbations of

> > > > asthma, and therapy should not be substituted abruptly for

inhaled

> > > or oral

> > > > corticosteroids.

> > >

> > >

> > >

> > >

[Guest guest]

Hi Lori,

I'm using Zyflo currently, working with a doctor through the company's

compassionate use program. I think the drug should start getting

marketed in the next few months. You can go to their website at

www.criticaltherapeutics.com.

I find that Zyflo works better than anything else available for

controlling my polyps and asthma. It's a pain to take (4 large pills

daily) and it's not a complete cure, but for me, nothing else has come

close. It's restored my sense of smell and kept me off the operating

table and off steroids since 2001.

You need to get your liver ALT level checked regularly if you use

Zyflo, because for a small number of people, it can cause serious

liver damage and even death. But if the numbers are good, it's very

effective.

-Mike

On 9/9/05, kelkeneth <kelkeneth@...> wrote:

> Does any one have any information about Zyflo. An answer would be

> appreciated.

>

> Lori in PA

>

>

>

>

>

>

>

[Guest guest]

Hi Mike, Thanks for your response, Zyflo is the only thing that works for me as well. I take it with 20 mg of accolate and just started taking it with 10 mg of singular. Both accolate and singular are basically the same but singular doesn't work as well as accolate for me. My allergist at Penn state started my on Prostoglandins as well. I haven't read that anyone one else is taking this, So, I don't really know it they will help. He also has me taking 1000 vitimin E and 1000 Fish oil.

Again, Thanks for the information. I will call the company regarding Zyflo.

Lori in PA. Condouris <condour@...> wrote:

Hi Lori,I'm using Zyflo currently, working with a doctor through the company'scompassionate use program. I think the drug should start gettingmarketed in the next few months. You can go to their website atwww.criticaltherapeutics.com.I find that Zyflo works better than anything else available forcontrolling my polyps and asthma. It's a pain to take (4 large pillsdaily) and it's not a complete cure, but for me, nothing else has comeclose. It's restored my sense of smell and kept me off the operatingtable and off steroids since 2001.You need to get your liver ALT level checked regularly if you useZyflo, because for a small number of people, it can cause seriousliver damage and even death. But if the numbers are good, it's veryeffective.-MikeOn 9/9/05, kelkeneth

<kelkeneth@...> wrote:> Does any one have any information about Zyflo. An answer would be> appreciated.> > Lori in PA> > > > > > >

[Guest guest]

Lori, please have your liver function monitored regularly. Singulair,

Accolate and Zyflo can all have effects on the liver, and I don't

think there are any studies about taking all three of them --but maybe

you can find out how they are metabolized. They might be metabolized

through the same pathway. This could cause problems in dosage, etc.

Why the Singulair and Accolate and not just the Accolate?

Good luck with all

Lori in NY

[Guest guest]

Lori, I do have my live function monitored regularly. My doctor at Penn State just recently added Singular to the mix. I supposed its like increasing my dose of accolate, without doing that, perhaps in the future, he will put me on a higher does of sigular and get me off the accolate, the sigular I believe is a safer drug.

Thanks for your concern, Lori in PA.truelori <lori@...> wrote:

Lori, please have your liver function monitored regularly. Singulair, Accolate and Zyflo can all have effects on the liver, and I don't think there are any studies about taking all three of them --but maybe you can find out how they are metabolized. They might be metabolized through the same pathway. This could cause problems in dosage, etc. Why the Singulair and Accolate and not just the Accolate? Good luck with allLori in NY

for Good Click here to donate to the Hurricane Katrina relief effort.

[Guest guest]

Patty, I take Zyflo, I started taking it in November I think it helps alot.

I have not noticed any adverse affects. I take it along with singulair.

Zyflo works differently than singulair. I don't know about the OTC warning

except that it can cause some problems with your liver and tylenol also can

cause liver problems. but I am not sure, I just know it works for me. I also

had surgery at the end of November. It went very well, some sort of new

procedure so I had little bleeding and did not require the major packing I

have had in the past. I didn't realize how bad I had been feeling until I

had the polyps out and felt so much better.I found that I feel much better

and function better if I am proactive about this and treat things before

they get really bad. (not my usual mode of operation).

Zyflo

> my ent just put me on Zyflo-- so far limited success with anything

> else, including Plumicort.

>

> Questions-- I am supposed to take this instead of Singular? How

> long does it take to see any benefits? It says not to take OTC

> drugs-- any known problems (like Tylenol which I take for frequent

> sinus headaches?)

>

>

> I seem to be left with only surgery if this does not work, but I

> can not bring my self to do it. Minor foot surgery (supposed to

> take 3 days to heal took over a year) Wisdom teeth left my face

> swollen for 6 wks. MD's baffled at amount of swelling. I am afraid

> I will not be able to work anymore if I have surgery. Any known

> drugs to take before surgery to prevent swelling (I could not find

> anything on the internet)

>

> Thanks!

> Patty

> suffering for 3 yrs now!

>

>

>

>

>

>

>

>

[Guest guest]

Bob,

My allergist tried the Singulair solution also (back in 2002). I think I did it

for 6 months, but

it didn't help. I never tried Zyflo. Aspirin desens has been the only thing that

has worked for

me.

Jim (Texas)

--- rpmarcus1 <rpmarcus@...> wrote:

---------------------------------

I've been a member for a couple of years but rarely post. My symptoms

don't seem to be as bad as some of you...my asthma is under control

and my nose is not really stuffy....my only problem is that I cannot

smell. I irrigate, use singulair, nasonex.

In my quest for smell, my allergist has had me dissolve singulair into

saline solution and use 2x per day (this evidently was based on a

recent study). I tried for 3-4 months but it did not work, no real

effect. Now, I'm starting Zyflo, hoping that this will return my

sense of smell. If this doesn't work, I'll be desensitized here in

St. Louis, but would like to avoid it if possible.

Has anyone had their sense of smell return with Zyflo? I will keep

you updated....

Bob in STL

[Guest guest]

My smell returned for quite a while with zyflo. Lately it's been bad because I've had a pretty bad string of sinusitis infections, but when I was conscienciously using the nasal steroid and zyflo I did very well. I'm now doing aspirin in conjunction with zyflo, and hope it will work as well for me as it has for everyone else.

On 1/18/06, Jim Brown <jim747@...> wrote:

Bob,My allergist tried the Singulair solution also (back in 2002). I think I did it for 6 months, butit didn't help. I never tried Zyflo. Aspirin desens has been the only thing that has worked forme.

Jim (Texas)--- rpmarcus1 <rpmarcus@...> wrote:---------------------------------I've been a member for a couple of years but rarely post. My symptoms

don't seem to be as bad as some of you...my asthma is under controland my nose is not really stuffy....my only problem is that I cannotsmell. I irrigate, use singulair, nasonex.In my quest for smell, my allergist has had me dissolve singulair into

saline solution and use 2x per day (this evidently was based on arecent study). I tried for 3-4 months but it did not work, no realeffect. Now, I'm starting Zyflo, hoping that this will return mysense of smell. If this doesn't work, I'll be desensitized here in

St. Louis, but would like to avoid it if possible.Has anyone had their sense of smell return with Zyflo? I will keepyou updated....Bob in STL

[Guest guest]

My sense of smell was great on Zyflo. However in the last couple of months it has been gone. I'm not sure why. Has anyone taken Remicade or any of the other anti-imflamatory meds for athritis? My Rhematologist is thinking about putting me on this for my arthritis, but I wonder if it will work like steriods for the rest of me.????? Lori in PA Condouris <condour@...> wrote: My smell returned for quite a while with zyflo. Lately it's been bad because I've had a pretty bad string of sinusitis infections, but when I was conscienciously using the nasal steroid and zyflo I did very well. I'm now doing aspirin in conjunction with zyflo, and hope it will work as well for me as it has for everyone else. On

1/18/06, Jim Brown <jim747@...> wrote: Bob,My allergist tried the Singulair solution also (back in 2002). I think I did it for 6 months, butit didn't help. I never tried Zyflo. Aspirin desens has been the only thing that has worked forme.Jim (Texas)--- rpmarcus1 <rpmarcus@...> wrote:---------------------------------I've been a member for a couple of years but rarely post. My symptoms don't seem to be as bad as some of you...my asthma is under controland my nose is not really stuffy....my only problem is that I cannotsmell. I irrigate, use singulair, nasonex.In my quest for smell, my allergist has had me dissolve singulair

into saline solution and use 2x per day (this evidently was based on arecent study). I tried for 3-4 months but it did not work, no realeffect. Now, I'm starting Zyflo, hoping that this will return mysense of smell. If this doesn't work, I'll be desensitized here in St. Louis, but would like to avoid it if possible.Has anyone had their sense of smell return with Zyflo? I will keepyou updated....Bob in STL

[Guest guest]

Hi,

I am new to this group,and have recently been diagnosed with Sampters.

My allergist is suggesting Zyflo. I have read the archives but there

isn't much talk recently. Any new thoughts? lj

[Guest guest]

Zyflo is a better choice for people with Samter's thatn Singulaire- actually

a very good choice. Carol

Zyflo

> Hi,

> I am new to this group,and have recently been diagnosed with Sampters.

> My allergist is suggesting Zyflo. I have read the archives but there

> isn't much talk recently. Any new thoughts? lj

>

>

>

>

>

>

>

[Guest guest]

> >

> > Zyflo is a better choice for people with Samter's thatn

Singulaire-

> actually

> > a very good choice. Carol

> > Zyflo

> >

> >

> > > Hi,

> > > I am new to this group,and have recently been diagnosed with

> Sampters.

> > > My allergist is suggesting Zyflo. I have read the archives but

> there

> > > isn't much talk recently. Any new thoughts? lj

> > >

> > >

> > >

> > >

> > >

> > >

> > >

[Guest guest]

Lori: No one drug works for everyone but since it does work higher up in the

pathway it hits it's targets in a more global fashion. Only a small

percentage get LFT problems so if you can tolerate the drug it is probably

the best on to start with IMHO. Carol

Zyflo

>>

>>

>> > Hi,

>> > I am new to this group,and have recently been diagnosed with

> Sampters.

>> > My allergist is suggesting Zyflo. I have read the archives but

> there

>> > isn't much talk recently. Any new thoughts? lj

>> >

>> >

>> >

>> >

>> >

>> >

>> >

[Guest guest]

I take them both plus prednison, mucinex, advair, and xolair.

From: janesmarino <janesmarino@...>Subject: Zyflosamters Date: Thursday, July 17, 2008, 7:37 PM

My doctor today is encouraging me to try Zyflo again. I tried it about a year ago, but wasn't able to tolerate it without getting a severe migraine. I am wondering if anyone has had the experience of migraine from Zyflo as I am not positive at this point that it was actually the Zyflo that caused the headaches. (I happen to be the Migraine Queen!) Also, I would be interested in any opinions as to whether those who have tried both Singulair and Zyflo feel they get greater benefit from one over the other.Thanks all!Jane

[Guest guest]

I currently take both Zyflo AND Singulair. According to my ENT and

Pulmonologist, It is safe and even though they are both beta blockers,

One is a uptake blocker ?? and the other is the opposite. (I cant

remember the correct terminology) . It works great and has really

changed my life!!!

[Guest guest]

I take all 3 everyday. About the pulmicort -- my surgeon told me NOT to use tap water but only DISTILLED water. My other surgeon said tap water was ok, but it really, really makes the difference. I was getting infections every time I irrigated and now I DO NOT with distilled water!

From: truelori <lori@...>Subject: Re: Zyflosamters Date: Wednesday, August 6, 2008, 5:29 PM

Zyflo and Singulair are not beta blockers. People with asthma are not supposed to take beta blockers, which are prescribed for high blood pressure, as they may make asthma worse.I know you said you weren't sure about the terminology, so I'm just correcting it for the group. Zyflo and Singulair are leukotriene modifiers, and Zyflo works further up the chain. There is no reason not to be on them both at once, as far as I know. But you might want to make sure to have your liver enzymes checked regularly, as both, ans especially Zyflo, may cause damage to the liver.Lori>> I currently take both Zyflo AND Singulair. According to my ENT and > Pulmonologist, It is safe and even though they are both beta blockers, >

One is a uptake blocker ?? and the other is the opposite. (I cant > remember the correct terminology) . It works great and has really > changed my life!!!>

[Guest guest]

The best irigation solution (most friendly to the ciliae) is Locke-Ringer

solution, and the

next best is saline.

> >

> > I currently take both Zyflo AND Singulair. According to my ENT and

> > Pulmonologist, It is safe and even though they are both beta

> blockers,

> > One is a uptake blocker ?? and the other is the opposite. (I cant

> > remember the correct terminology) . It works great and has really

> > changed my life!!!

> >

>

[Guest guest]

As Lori said, check your liver function every once in a while - both Zyflo and

Singulair tax

the liver - and why not check the kidneys at the same occasion.

> >

> > I currently take both Zyflo AND Singulair. According to my ENT and

> > Pulmonologist, It is safe and even though they are both beta

> blockers,

> > One is a uptake blocker ?? and the other is the opposite. (I cant

> > remember the correct terminology) . It works great and has really

> > changed my life!!!

> >

>